病区范围与流行规律

大骨节病是一种病因未明、严重危害人民身体健康的地方性骨关节病,俗称“柳拐子病”。该病在我国流行较久,明朝末年山西安泽县志和清朝末年吉林长白山江岗志略都有关于大骨节病的描述。近年来全国病情业已查明,在黑龙江、吉林、辽宁、北京、内蒙古、河北、山东、山西、河南、陕西、甘肃、青海、四川、西藏等14个省、直辖市、自治区中的302个县有大骨节病流行。现症病人170多万,受威胁人口达4000多万。其中尤以黑龙江、陕西、吉林、甘肃、内蒙古等五省,自治区的病区范围广,病人多,病情重。大     

我国北方克山病流行概况

克山病在我国北方流行已有百余年的历史。解放前,东北、华北和西北的一些地区,该病经常发生大流行。每当克山病暴发,病区景象十分凄惨,以致引起中外医学界的震惊。建国后,党和人民政府十分关心病区群众的疾苦,投放了大量的人力、物力和财力,使防治工作取得了显著成效。1960年,党中央决定由专门机构负责该病的防治工作,22年来克山病的发病和病死率大幅度下降。现将我们所获得的北方病区1959～1980年间克山病病情资料,     

联合型瑞文测验辽宁城市和农村儿童智商常模的研制

目的：研制联合型瑞测验辽宁城市和农村儿童商常模（ＣＲＴ－ＬＮＣ、ＣＲＴ－ＬＮＲ）。方法用联合型瑞测验对城市、农村５－１４岁儿童取样。结果城市与农村儿童各年龄组原始得分差异显（ｔ＝２．８６－８．２４）,同年龄组的男、女儿童原得分均无显差异（城市ｔ＝０．０７－０．７７,农村ｔ＝０．０２－０．９１）;测题难度达到理想值（ＣＰ＝０．３－０．７,城市５６．８７％,农村６１．４３％）;区分度较好（ｒ〈     

补碘后出生儿童骨龄和体格发育与智商水平的关系

目的：了解重,中度碘缺乏病区供应碘盐后出生儿童的骨龄和体格发育状况与智商水平的关系。方法：CRT－C2测7－14岁儿童智商,拍手腕骨X线片判定骨龄,标准量具测身高,体重,结果：碘盐预防后出生儿童的骨龄,身高,体重发育落后率均随人群智商（IQ）水平提高而下降,IQ50－69组儿童骨龄,身高,体重落后率分别为18．3％,17．6％,10．2％,均显著高于IQ70－79,IQ80－119,IQ大于等于120三组儿童（P＜0．01）,轻度智商落后组儿童的骨龄发育落后以尺骨未按时出现为常见,体格发育障碍为身高落后者明显多于体重落后者,骨龄与身高发育落后程度一致。结论：补碘后碘缺乏病区儿童骨龄和体格发育与智商水平密切相关,轻度智商落后组儿童的骨龄,身高,。体重 状况显著落后于同期出生智商水平较高组儿童。     

碘缺乏病区食用碘盐和碘油碘盐并用学生碘营养状况

目的：观察新确定碘缺乏病区食用碘盐和碘油碘盐并用的两组学生防治前后甲肿率和尿碘水平；补碘后甲肿学生的甲状腺体积回缩情况。方法：在观察前和观察1年后检测学生甲状腺体积和尿碘，甲状腺体积用日本Aloks SSD 500型B超仪测量，尿碘含量用酸消化砷－铈接触法测定。结果：碘盐防 且学生甲肿率由8．8％下降到7．3％，尿碘水平由77．1μg/L 上升到138．0μg/L；碘油碘盐防治组学生甲肿率由9．7％下降到3％，尿碘水平由86．3μg/L上升到283．2μg/L。结论：原“非碘缺乏病区”学生也存在碘营养不足；补碘防治1年碘油碘盐并用组学生甲肿率、尿碘水平均达到消除碘缺乏病的指标，而食用碘盐组学生甲肿率未达标。     

碘缺乏对农村地区儿童骨龄和体格发育影响

骨龄是评价儿童骨发育的指标，身高和体重是评价儿童体格发育的指标。为了解和比较农村非缺碘地区、碘盐防治碘缺乏病（IDD）轻病区和未补碘IDD轻病区同时期出生儿童骨龄、身高、体重发育状况，我们于2001年对辽宁省部分农村地区儿童进行了手腕骨X线拍片和身高、体重测量。结果报告如下。     

辽宁省碘缺乏病病区不同补碘时期出生儿童智力水平调查

objecfive To know and compare the intelligence level of children born in different time periods in regions with iodine deficiency disorders(IDD)in Liaoning province.Methods All 7-14 year-old children from ten schools were chosen as the subjects respectively from six villages in each of the six counties and in regions with iodine deficiency,who were respectively born at the initialization of iodinated salt supplying period(1978-1980);non-iodinated salt supplying period(1981-1990);recovery of supplied iodized salt period(1991-1995);universal iodized salt period(1996-2000),respectively.Intelligence quotient(IQ)was measured by Combined Ravens Test in China(CRT-C)and Combined Ravens Test-the Rural,in China,2nd edition(CRT-RC2).Results IQ of children during the non-iodized salt period(91.9±14.3)was significantly lower than the initial supply of iodized salt period(95.8±14.6,q=8.60,P<0.01),recovery of supplied iodized salt period(99.7±14.7)was significantly higher than the initial supply of iodized salt period, non-iodized salt sales period(q = 9.53, 18.13, all P < 0.01 ),universal salt iodization( 104.3 ± 14.9) was significantly higher than the initial supply of iodized salt period, non-iodized salt sales period, recovery of supplied salt iodization(q = 20.00,28.00,10.46, all P < 0.01). Children's rate of mental retardation (IQ≤69) was higher in non-iodinated salt supplying period (6.7%, 88/1314 ) than the initial supply of iodized salt (4.4%, 21/471, χ2 = 3.85, P < 0.05), recovery of supplied iodized salt period(3.3%,48/1470) was significantly lower than non-iodinzed salt supplying period (χ2 = 15.37, P < 0.01), universal salt iodization period(2.7%, 36/1344) was lower than the initial supply of iodized salt period(χ2 = 4.41, P < 0.05) and non-iodinzed salt supplying period(χ2 = 26.34, P < 0.01 ). The IQ and intelligent retarded rates in children born during the initial years of iodinated salt supplying period were not different. The IQ of the children during ten years of non-iodized salt supplying period fluctuated in a "∪" curve, while the intelligent retardation rates in a "∩" curve.The children born during the period of recovery supplied iodized salt increased their IQ and lowered the retardation rates year after year. The IQ of the children in universal iodized salt period kept on increasing while intelligent retarded rates reduced to the lowest level. Conclusions The intelligence level of children born in regions with IDD during non-iodized salt supplying period is remarkably lower than that of the beginning years of iodinated salt supplying period. The intelligence level of children born after universal iodized salt period is remarkably higher than that of the initial iodinated salt supplying period and recovery of supplied iodized salt period, respectively.     

农村非IDD病区智力正常儿童精神运动成套测验的检测结果分析

目的:掌握非IDD病区智力正常儿童精神运动成套测验的正常值,为制定全国儿童精神运动测验量表提供依据。方法:按“九五”国家医学科技攻关项目的设计,在沿海和内陆平原农村非IDD病区对IQ80～119的无甲肿7～14岁儿童进行10项精神运动测验。结果:选择反应时测验的反应时间(ms)间隔均值是由小年龄组向大年龄组逐渐递降,相临两个年龄组差异显著(P<0.01或P<0.05);连续作业、划消数字、目标追踪、符号记入、数字符号、转动插棒6项测验的个数(次)均值,均由小年龄组向大年龄组逐渐递增,相临两个年龄组差异显著(P<0.01或P<0.05);连续数字测验的从①连到(25)所用时间(秒)均值,三对相临年龄组差异不显著(P>0.2或P>0.05);视觉保持测验的辨别、记忆图形准确个数均值,多数相临两个年龄组差异不显著(P>0.5);动作稳定测验的数值均值,其相临两个年龄组差异均不显著(P>0.5)。结论:选择反应时、连续作业、划消数字、目标追踪、符号记入、数字符号、转动插棒7项测验的检测结果可信,能编制精神运动测验量表,进行实证研究及用于诊断轻度精神运动障碍。     

碘缺乏病病区轻度智力落后儿童精神运动测验结果评价

目的　验证津医精神运动成套测验（ＪＰＢ）检查轻度智力落后儿童精神运动障碍的灵敏度，评估碘缺乏病（ＩＤＤ）病区亚克汀病患病率。方法　对中国联合型瑞文测验智商常模（ＣＲＴ－Ｃ２）判定的４１５ 名７～１４ 岁轻度智力落后儿童进行ＪＰＢ检查，用Ｔ 分数与损伤指数确定其精神运动功能状况。结果　Ｔ 分数确定的ＪＰＢ检出ＩＤＤ 重、中病区ＩＱ ５０～６９ 儿童精神运动功能异常率为５７．８％ ，其中ＩＱ ５０～５９ 人群异常率达７０．９％ ；损伤指数确定的异常率与Ｔ 分结果差异不显著（ Ｐ＞ ０．０５）。结论　ＪＰＢ是发现和定量描述轻度智力落后儿童精神运动功能障碍的有效实用方法，可用于诊断亚克汀病。     

我国大骨节病流行概况

大骨节病解放前就在我国1111东北、西北、华北的一些地方严重流行。新中国成立后,党和人民政府在病区和医学院校相继建立了防治研究机构,广泛的进行了流行病学调查。本文对我国大骨节病的流行情况概述和分析如下。一、病区分布规律1950年初步调查,大骨节病分布在辽