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Objective: To assess embryo implantation rate (IR) and pregnancy rate (PR) in women who received Bushen Wengong Decoction (补肾温宫汤, BSWGD), a Chinese herbal formula, combined with low dose of human menopausal gonadotropin (hMG) prior to frozen-thawed embryo transfer (FET). Methods: A total of 262 subjects (674 transferred embryos) who received FET were analyzed retrospectively. In them, 122 women were under 30 years old, 106 between 30-35 years and 32 over 35 years. The 85 subjects with normal ovulation were assigned to Group A, the natural menstruation cycling group, on whom no pre-transfer treatment was applied. The other 177 subjects with abnormal ovulation were assigned to Group B, and subdivided, according to the pre-transfer treatment they received, into three groups, Group B1 (50 cases) received BSWGD, Group B2 (58 cases) received hMG and Group B3 (69 cases) received both BSWGD and low dose hMG. The IR and PR of FET in the four groups were compared time on PR of FET were compared also. Besides, the influencing factors and the effect of the embryo cryoto FET were analyzed. Results: IR and PR were significantly higher in all age sects of Group B3 than those in Group A, showing significant difference ( P〈0.05). IR and PR in subjects in age sects of 〈30 years and 〉 35 years in group B3 were significantly higher than those in Group B1 ( P〈0.05), but no significant difference was shown in the two parameters between Group B 2 and Group B3 (P〉0.05). PR in the subjects who received embryos with cryo-time of 〉 200 days was significantly lower than that in those with cryo-time of ~ 100 days (P〈0.05). Embryo cryo-time, endometrial thickness, use of BSWGD and use of hMG were of significance in FET ( P〈 0.05). Conclusion: A programmed cycle of BSWGD combined with low dose of hMG could improve the embryo IR and PR of FET. Embryo cryo-time, endometrial thickness, and the use of BSWGD and hMG are of significance for FET. 相似文献
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彩色多普勒超声监测子宫内膜和内膜下血流对IVF患者子宫容受性的预测价值 总被引:3,自引:0,他引:3
目的:评价彩色多普勒超声监测子宫内膜和内膜下血流在IVF-ET中对子宫内膜容受性的预测价值。方法:选择第一次进行IVF/ICSI-ET治疗的不孕症患者119例,根据注射hCG日子宫内膜和内膜下血流状况分为A组(n=8):子宫内膜和内膜下血流≤2支;B组(n=50):子宫内膜和内膜下血流3-4支;C组(n=61):子宫内膜和内膜下血流≥5支。各组患者均移植1-3个胚胎。比较各组的临床特征、卵巢反应、内膜情况和妊娠结局。结果:各组的临床特征、卵巢反应、内膜情况均无统计学差异,A组妊娠率低于B组(P<0.05)和C组(P<0.01)。A组着床率低于C组(P<0.01),B组和C组的妊娠率和着床率均无明显差异(P>0.05)。结论:子宫内膜和内膜下血流在IVF-ET中对子宫内膜容受性有一定预测价值。IVF-ET周期中内膜和内膜下血流≤2支者建议当月不做胚胎移植,可待血流改善后再行胚胎移植术。 相似文献
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整合和共享生物样本资源,是盘活我国生物样本存量、提高生物样本使用效率的最有效途径。近年来,我国生物样本库建设虽取得了显著成就,但样本资源共享工作仍未得到有力推进。本文采用内容分析的方法,总结出样本库建设标准不统一、样本库行政管理不到位、样本共享伦理监管不健全等11个问题。 相似文献
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目的从国家自然科学基金角度宏观分析近年我国医学基础研究重点学科/领域及其发展趋势,为促进我国医学基础研究的科学发展提供重要的基础。方法对国家自然科学基金委公布的医学科学部2009~2013年所有立项项目.采用描述性统计方法进行分析。结果本研究定量分析了2009~2013年我国医学及其子领域获取国家自然科学基金的经费量及其变化趋势,并对临床医学和预防医学进行详细分析。结论本研究从定量分析角度总结评价了当前我国医学基础研究中的重点/薄弱领域及发展趋势增强/减弱的领域,可为我国医学科技发展战略/规划及科技管理研究提供重要参考。 相似文献
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