航渡营养口粮抗疲劳实验研究

目的：评价航渡营养口粮抗疲劳功能。方法：50只小鼠随机分成氨基酸低，中，高剂量组，混合饲料组和对照组，进行运动耐力测定，血清尿素氮浓度测定和血糖测定。结果：给予氨基酸的小鼠，与对照组比较负重游泳时间明显延长（P＜0．05），小鼠负重游泳至力竭时血清尿素氮浓度明显降低（P＜0．01），氨基酸高剂量组和混合饲料组小鼠血糖水平高于对照组。结论：航渡营养口粮能有效地提高小鼠机体运动耐力，维持血糖水平，降低血清尿素氮浓度，抗疲劳。     

Effect of 6-hydroxydopamine lesions of the amygdala on intravenous cocaine self-administration under a progressive ratio schedule of reinforcement

Bilateral six-hydroxydopamine (6-OHDA) lesions were placed in the amygdala of rats self-administering cocaine (1.5 mg/kg per injection i.v.) under a progressive ratio schedule of reinforcement. Post-lesion access to three doses of cocaine (1.5, 0.75 and 0.37 mg/kg per injection i.v.) revealed a lesion effect only at the highest dose. At this dose, the lesion caused a significant increase in breaking point. No change in the breaking point was produced at the lower two doses. The biochemical results show a significant reduction in dopamine and DOPAC levels within the amygdala and an increase in dopamine within the NACC. In contrast, noradrenaline and serotonin (5-HT) levels were unaffected by the lesion in any of the dissected areas. These results demonstrate that no specific effect on cocaine reinforcement was produced by 6-OHDA lesions of the amygdala. The possibility that the lesion may have attenuated the anxiogenic qualities of the high dose of cocaine is discussed.     

城市暂住人口结核病调查分析

目的分析城市暂住人口结核病控制中存在的问题，为政府制定新的政策和采取新的措施进一步控制结核病流行提供依据。方法对上海市闵行区疾病预防控制中心1997～2002年结核病报表资料进行分析。结果暂住人口结核病新登记率远高于户籍人口，而其实际的流行情况可能更加严重。暂住人口结核病患者的发现方式与户籍人口类似。但是，暂住人口结核病的病例管理、治疗管理差及治疗效果较差，防治管理工作亟待改善。结论要进一步控制城市的结核病流行，除了在提高结核病发现率方面采取措施外，应重点加强暂住人口的结核病患者管理和规范治疗。     

D101吸附树脂再生工艺实验研究二:再生液流量、用量及温度对再生效果的影响

目的研究D101吸附树脂的再生活化工艺.方法采用正交试验法,以树脂比吸附量作为参考指标,考察酸、碱两种再生液的流量(A)、用量(B)、温度(C)三个因素对再生效果的影响.结果两种再生液的流量、用量、温度经优化后提示为A1B3C3.结论 D101树脂再生活化时,当再生液的酸、碱、乙醇浓度选择0.05mol·L-1NaOH的75%乙醇溶液和0.1mol·L-1HCl的90%乙醇溶液时,其的流量、用量、温度应为1.0SV、5.0BV,30℃.     

Lack of repercussions of sleep apnea syndrome on recovery and attention disorders at the subacute stage after stroke: A study of 45 patients

IntroductionSleep apnea syndrome (SAS) frequently occurs after a stroke. Its association with a poor prognosis is open to discussion.ObjectiveTo study, in a physical and rehabilitation medicine (PRM) unit, the possible repercussions of SAS on neurological and functional recovery as well as attentional abilities following a stroke.Patients and methodsForty-five patients, all of whom had recently had a stroke without previously documented SAS, were screened using the ApneaLink^® system. An apnea-hypopnea index (AHI) score ≥10 was considered as indicative of SAS. The NIHSS, Fugl-Meyer (FM) and Functional Independence Measure (FIM) Scales were applied on admission and at two months as means of assessing neurological and functional recovery, which was expressed by the difference between the first and the second scores (delta FM, delta NIHSS, delta FIM). The Battery Attention William Lennox (BAWL) Test was given once in order to evaluate attention disorders. SAS severity was categorized according to the AHI. We compared the groups formed (mild, moderate and severe) using the same method.ResultsTwenty-eight patients (62.2%) presented AHI ≥ 10. Stroke characteristics were comparable in the SAS+ and the SAS– groups, with average post-stroke time lapse of 26 days, initial average FIM score of 71.2 points ± 26.3 and initial average NIHSS score of 8.9 ± 4.9. The demographic characteristics of the two groups were likewise comparable with the exception of age, as the SAS+ group was pronouncedly older (65.4 vs. 53.5 years). As for delta FIM, which evaluated functional recovery, it averaged 31.8 ± 20.6. Cases of SAS were found to be mild (37.1%), moderate (28.6%) or severe (34.3%). No significant difference was observed on admission or at 2 months as regards the clinical scales or the BAWL test between the two groups or according to severity, except for the NIHSS score at 2 months in the severe sub-group.Discussion and conclusionThis study did not demonstrate the supposed repercussions of SAS on the recovery or attentional abilities of post-stroke patients. The tests were maybe given too early; they should take place at a lengthier time interval after the stroke, and also to be more complete.