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排序方式: 共有882条查询结果,搜索用时 31 毫秒
1.
目的研究手外科温箱对手外伤患者伤口或创面愈合,以及再植手指或手成活的影响。方法同期对手外伤术后应用手外科温箱治疗59例,应用烤灯治疗54例,观察效果。结果手外科温箱治疗59例,再植手指成活率97%,伤口一期愈合率96%,感染率4%;烤灯治疗54例,再植手指成活率90%,伤口一期愈合率92%,感染率8%。结论手外科温箱能提供观察、照明、保温、保湿、供氧、消毒、操作等功能,再植手指成活率和伤口一期愈合率明显上升,感染率明显下降,是手外科必备治疗康复设备。 相似文献
2.
Masahiro Nishihara Ryo Sumimoto Yasuhiko Fukuda James H. Southard Toshimasa Asahara Kiyohiko Dohi 《Surgery today》1997,27(7):645-650
In this study, we tested the effect of donor fasting with or without the use of an essential fatty acids deficiency (EFAD)
diet in the recipient using rat heart, pancreas, and liver transplant models. We then compared the survivals, tumor necrosis
factor alpha (TNF-α) response, and white cell accumulation in rats in order to clarify the mechanisms of the beneficial effect
of donor fasting and recipient EFAD. It was found that when the grafts were obtained from fasted donors and then transplanted
into fed recipients, the survival rate was significantly higher for all three grafts than for those obtained from fed rats
and transplanted into fed rats. The best survival was seen for pancreas grafts obtained from fasted donors and then transplanted
into EFAD recipients. TNF-α secretion was significantly suppressed in both fasted and EFAD rats, and both the total cell count
and neutrophil count were suppressed in EFAD rats. These results clearly indicate that in addition to liver grafts, both heart
and pancreas grafts obtained from fasted animals are more tolerant to warm ischemic injury. Furthermore, the combination of
donor fasting and recipient EFAD acts synergistically to inhibit the post-transplantation inflammatory reaction (through decreased
TNF-α secretion and white cell accumulation), thus resulting in an improved survival. 相似文献
3.
Kozo Hirata Tetsuo Nagasaka Tadahiro Nunomura Michel Cabanac 《European journal of applied physiology》1988,58(1-2):92-96
Summary The effects of local heating on finger blood flow (BF) and local thermal sensation (Sens
w
) were studied. Finger BFs in both hands were measured simultaneously; one hand was immersed in water the temperature (T
w
) of which was raised from 35° C to 43°C by steps of 2° C every 10 min, while the other hand was kept atT
w
35°C. FingerBF in the locally heated hand decreased atT
w
37 to 41°C, while fingerBF in the control hand did not alter. Sensw, in the heated hand showed a dynamic response, initially increasing concomitantly with an increase inT
w
, then gradually returning and adapting to a new level of Sensw. The dynamic response of Sensw, was not perceived during mental calculation even whenT
w
was raised to 40°C, and the reduction in finger blood flow was not observed. These results suggest that finger vasoconstriction caused by local heating closely relates to the dynamic response characteristic of local thermal sensation atT
w
above core temperature, and that the perception of local thermal sensation in the central nervous system is involved in the mechanism of this vasoconstrictor response. 相似文献
4.
目的 观察公民逝世后器官捐献原位肝移植术后早期肝功能不全(early allograft dysfunction,EAD)的发生情况,探讨早期肝功能不全的危险因素。方法 回顾性分析2017年1月至2019年12月间我院65例行肝移植供、受体资料。根据术后情况将患者分为EAD组(n=29)及非EAD组(n=35)。对相关因素先进行单因素分析,然后将统计学差异的因素进行多因素Logistic回归模型分析。结果 65例原位肝移植患者术后早期肝功能不全的患者有29例,发生率为44.6%。单因素分析显示EAD组与非EAD组供体血清钠[(157.53±21.71)mmol/L vs(146.06±15.24)mmol/L,P=0.019]、热缺血时间[(21.6±6.5)min vs(10.6±4.3)min,P=0.016]、冷缺血时间[(8.3±1.2)h vs(5.4±1.2)h,P=0.012]、ICU住院时间[(78.1±19.5)h vs(49.7±17.6)h,P=0.007]及受体的无肝期时间[(98.3±16.3)h vs(66.0±17.6)h,P=0.037]差异均有统计学意义。多因素Logistic回归分析结果显示影响术后早期肝功能不全的独立危险因素为供体血清钠水平(OR 18.372,95%CI 1.846~24.173,P=0.019)及热缺血时间(OR 8.105,95%CI 1.513~37.205,P=0.013)。结论 供体血清钠水平及热缺血时间是公民逝世后器官原位肝移植术后EAD的独立危险因素。 相似文献
5.
常温氧合血性心停搏液持续灌注心肌保护效应的实验研究 总被引:2,自引:0,他引:2
目的 采用随机对比的实验研究方法从测定心肌酶学、氧自由基代谢产物及心肌特异性蛋白几个方面来探讨冷晶体心停搏液间断灌注及常温氧合血性心停搏液连续灌注两种灌注方法的心肌保护效应。方法14只犬随机分为①对照组:冷晶体心停搏液间断灌注;②实验组:常温氧合血性心停搏液连续灌注。采集不同时点的犬冠状静脉窦血为测定标本,测定心肌特异性酶CK-MB、心肌特异性钙蛋白T(cTn-T),氧自由基代谢产物丙二醛(MDA)。结果对照组在主动脉开放后,CK-MB、MDA、cTn-T明显升高,实验组升高幅度较小。两组间比较有显著差异(P<0.01)。结论常温氧合血性心停搏液连续灌注,可以充分保证心肌在常温停跳期间的血供和氧供,避免了心肌缺血缺氧,明显地减轻了心肌缺血再灌注损伤,是一种非缺血性、比较理想的心肌保护方法。 相似文献
6.
To evaluate the role of thromboxane A2 (TXA2) in ischemic liver injury, the serum changes in thromboxane B2 (TXB2) and 6-keto-prostaglandin F1 alpha (6-K-PGF1) following warm ischemia of the total canine liver were examined, and the protective effect of a TXA2 synthetase inhibitor was assessed. Total liver ischemia was performed for 60 min on two groups of dogs: a control group, in which ischemia alone was performed, and an OKY-046 group, which received a TXA2 synthetase inhibitor. A temporary active portacaval shunt was used to eliminate the effects of splanchnic venous stasis during clamping of the hepatic pedicle. Postoperative changes in liver function, assessed by the transaminase enzyme levels, and in prostaglandins were recorded and the histologic liver findings of both groups 1 week after ischemia were compared. The levels of 6-K-PGF1 increased after reperfusion in both groups, while those of TXB2 increased in the control group but maintained low levels in the OKY-046 group. Liver function was better and histologic changes less marked in the OKY-046 group than in the control group, suggesting the important role of TXA2 in ischemic liver injury and the usefulness of a TXA2 synthetase inhibitor for protecting the liver against ischemic injury. 相似文献
7.
浅谈王士雄对疫病的防治 总被引:1,自引:0,他引:1
论述清代著名温病学家王士雄对疫病的防治思想,从环境卫生、住房、饮食及药物防治等方面作了总结,其经验对后世疫病防治具有一定的现实意义。 相似文献
8.
《山东中医药大学学报》2018,(1):70-73
从病名、病因病机、辨证治疗三个方面总结历代医家对伏暑的认识。认为伏暑起源于《黄帝内经》,《丹溪心法附余》最早将伏暑定为病名。直至清代各医家才明确认识到,伏暑是由于夏月摄生不慎,感受暑邪,潜伏体内,至秋季为时令之邪所引发的一类温病。伏暑的病因包括内因和外因两种,而外因又有先因与诱因之分,伏暑的发病与邪气性质、正气强弱、季节时令三方面因素密切相关。历代医家分别从辨邪气性质、三焦辨证、脏腑辨证等不同辨证体系进行治疗。辨伏邪的性质需先辨明是暑热还是暑湿,再分虚实,三焦辨证是以三焦为纲分别对太阴、阳明、少阴、厥阴伏暑加以论治,脏腑辨证则是根据邪气所伏脏腑之不同探讨相应治法。 相似文献
9.
Hong Chee Chew Arjun Iyer Mark Connellan Sarah Scheuer Jeanette Villanueva Ling Gao Mark Hicks Michelle Harkness Claudio Soto Andrew Dinale Priya Nair Alasdair Watson Emily Granger Paul Jansz Kavitha Muthiah Andrew Jabbour Eugene Kotlyar Anne Keogh Kumud Dhital 《Journal of the American College of Cardiology》2019,73(12):1447-1459
Background
Transplantation of hearts retrieved from donation after circulatory death (DCD) donors is an evolving clinical practice.Objectives
The purpose of this study is to provide an update on the authors’ Australian clinical program and discuss lessons learned since performing the world’s first series of distantly procured DCD heart transplants.Methods
The authors report their experience of 23 DCD heart transplants from 45 DCD donor referrals since 2014. Donor details were collected using electronic donor records (Donate Life, Australia) and all recipient details were collected from clinical notes and electronic databases at St. Vincent’s Hospital.Results
Hearts were retrieved from 33 of 45 DCD donors. A total of 12 donors did not progress to circulatory arrest within the pre-specified timeframe. Eight hearts failed to meet viability criteria during normothermic machine perfusion, and 2 hearts were declined due to machine malfunction. A total of 23 hearts were transplanted between July 2014 and April 2018. All recipients had successful implantation, with mechanical circulatory support utilized in 9 cases. One case requiring extracorporeal membrane oxygenation subsequently died on the sixth post-operative day, representing a mortality of 4.4% over 4 years with a total follow-up period of 15,500 days for the entire cohort. All surviving recipients had normal cardiac function on echocardiogram and no evidence of acute rejection on discharge. All surviving patients remain in New York Heart Association functional class I with normal biventricular function.Conclusions
DCD heart transplant outcomes are excellent. Despite a higher requirement for mechanical circulatory support for delayed graft function, primarily in recipients with ventricular assist device support, overall survival and rejection episodes are comparable to outcomes from contemporary brain-dead donors. 相似文献10.
目的:通过分析广东省第二人民医院收治的新型冠状病毒肺炎(以下简称新冠肺炎)患者的临床资料,从中医临床证候探讨该病在岭南地区的疫性特点,更好地指导临床辨证治疗。方法:收集广东省第二人民医院收治的36例新冠肺炎患者的临床资料,其中输入病例20例,本地病例16例,分析全部病例、输入病例和本地病例的临床资料和证候特点。结果:新冠肺炎患者年龄分布较广,平均年龄45岁,以男性居多,55.56%的患者为外地输入病例,44.44%的患者为本地感染病例。全部病例证型以湿邪郁肺型和邪热壅肺型为主,分别占44.44%和38.89%;91.67%的患者呈现“湿”的病理特点,72.22%的患者呈现“热”的病理特点。其中输入病例证型以湿邪郁肺型为主,占65.00%,100%的患者呈现“湿”的病理特点,55.00%呈现“热”的病理特点;本地病例证型以邪热壅肺为主,占56.25%,93.75%的患者呈现“热”的病理特点,81.25%呈现“湿”的病理特点。结论:本次疫病在岭南地区的疫性属于以湿邪和热邪为主导的“湿热疫”,病机特点为湿热并重;输入性病例多表现为以湿邪为患的“湿疫”,有化热的趋势和倾向,病机特点为湿重于热;本地病例多表现为以热邪为主的“温热疫”,病机特点为热重于湿。此次新冠肺炎不同地区存在不同疫性的可能,辨证和治疗要遵守三因制宜的原则。 相似文献