八段锦治疗神经根型颈椎病的系统评价与Meta分析

[目的] 系统评价八段锦治疗神经根型颈椎病的临床疗效。[方法] 计算机检索中国知网数据库（CNKI）、维普资讯中文科技期刊数据库（VIP）、万方数据库（Wan-fang）、中国生物医学文献数据库（SinoMed）、Web of science、Clinical Trials gov、Pubmed、EMBASE、CENTRAL、Cochrane Library，查找出八段锦治疗神经根型颈椎病的随机对照试验（RCT），检索时限均从建库至2019年7月1日。两名研究者按照纳入与排除标准独立进行文献筛选、资料提取和偏倚风险评估，应用RevMan 5.3软件对最后纳入的研究进行Meta分析。[结果] 最终纳入10个RCT，共843例患者。Meta分析结果显示：八段锦+常规治疗与常规治疗比较，其临床疗效的总有效率差异具有统计学意义[OR=4.19，95% CI（2.42，7.26），P<0.000 01]；八段锦+常规治疗与常规治疗+颈部“米”字操比较，其临床疗效的总有效率差异具有统计学意义[OR=3.41，95% CI（1.56，7.46），P=0.002]；八段锦+常规治疗与常规治疗比较，其疼痛视觉模拟评分法（VAS）评分差异具有统计学意义[MD=-1.90，95% CI（-1.97，-1.83），P<0.000 01]。[结论] 基于现有的研究，该系统评价显示，与常规治疗相比，八段锦+常规治疗在临床疗效总有效率、VAS评分方面有一定的治疗优势。与常规治疗+颈部“米”字操比较，八段锦+常规治疗在临床疗效的总有效率方面有一定的治疗优势。但由于纳入研究的质量不高，仍需要大样本、多中心、随机、双盲试验及试验参照CONSORT标准和STRICTA声明进行RCT研究。     

八段锦干预心力衰竭患者疗效的Meta分析

目的:评估八段锦干预心力衰竭的疗效及安全性。方法:搜索中国知网数据库、中国生物医学文献数据库、万方数据库以及维普中文全文数据库；PubMed、Cochrane Library、web of science、EMBASE。检索时间为建库至2019年2月28日。对纳入的随机对照试验（RCT)用Cochrane手册进行偏倚风险评估，用Rev Man 5.3软件进行Meta分析。结果:纳入6篇文献，7个随机对照研究，共计543例心力衰竭患者。与对照组比较，观察组MLHFQ减少[MD=10.88,95%CI=（8.22，13.54）]，6分钟步行试验(6MWT)提高[MD=107.81,95%CI=（75.83，139.78）]，左心室射血分数(LVEF)提高[MD=3.62,95%CI=（2.04，5.19）]，B型利钠肽(BNP)降低[MD=73.32,95%CI=（45.12，101.53）]，临床疗效[OR=4.00,95%CI=（1.35，11.83）]，中医证候评分[OR=4.57,95%CI=（2.03，10.31）]。结论:八段锦可改善心力衰竭患者的心功能，用于稳定期的康复治疗。     

八段锦对视神经脊髓炎谱系疾病恢复情况的研究

[目的]评估规律性八段锦运动对视神经脊髓炎谱系疾病患者残疾状态及日常生活能力恢复情况的影响。[方法]选取视神经脊髓炎谱系疾病患者58例,随机分成试验组和对照组,每组29例,分别给予常规药物治疗+基础训练+八段锦干预、常规药物治疗+基础训练,疗程12周。比较两组扩展残疾状态量表(EDSS)评分、Barthel指数、Ashworth评分和疲劳严重度量表(FSS)评分的变化情况。[结果]试验组中,患者的EDSS评分、Barthel指数、Ashworth评分和FSS评分较干预前明显改善,差异具有统计学意义(P0.05);与对照组比较,EDSS评分和Barthel指数改善具有统计学意义(P0.05)。对照组中,患者Barthel指数、Ashworth评分和FSS评分较干预前明显改善(P0.05)。两组这4项指标的改善程度比较中,与对照组比较,试验组在EDSS评分、Barthel指数、Ashworth评分和FSS评分的改善程度更明显(P0.05)。[结论]规律的八段锦干预能明显改善视神经脊髓炎谱系疾病患者残疾状态、日常生活能力、肢体痉挛程度和疲劳状态,适合临床推广应用。     

Baduanjin exercise improved premenstrual syndrome symptoms in Macau women

ObjectiveTo investigate the effect of Baduanjin, a traditional Chinese medical exercise, on improving premenstrual syndrome (PMS) symptoms in women.MethodsForty reproductive age women with PMS in Macau practiced standardized Baduanjin exercise for three menstrual cycles. A questionnaire, the daily record of severity of problems (DRSP), was used to measure symptom severity. DRSP was filled out every day starting from the last cycle before exercise (i.e., the first menstrual cycle) to the third cycle after exercise initiation (i.e., the fourth menstrual cycle). The total scores and the scores of each item during the 5 premenstrual days and follicular phase (5-9 postmenstrual days) were calculated.ResultsAfter exercise, the total DRSP scores during the 5 premenstrual days and differences in the total DRSP scores between the 5 premenstrual days and the follicular phase were both significantly reduced. Of note, the physical symptom total scores in the 5 premenstrual days and the differences between its total score in the 5 premenstrual days and in the follicular phase were both significantly reduced. The differences between the total scores of depressed mood, anxious mood, loss of interest, and reduction in social activity during the 5 premenstrual days and the follicular phase were also reduced.ConclusionsBaduanjin exercise was able to improve the mental and especially the physical symptoms of PMS.     

Effects of Baduanjin on glucose and lipid metabolism in diabetic patients: A protocol for systematic review and meta-analysis

Background:Baduanjin is an ancient technique of physical and breathing exercises (Dao Yin). This technique is divided into eight sections and each section is a motion, so it is called “Baduanjin”. It is practice without equipment, simple and easy to learn, whose effect is significant leading to good fitness effect. Diabetes mellitus is a chronic metabolic disease. Clinical studies have reported that Baduanjin can affect the metabolism of blood glucose and blood lipid in diabetic patients, but the reported efficacy is different among different studies. Therefore, the study is aimed to systematically evaluate the size and differences of the impact of Baduanjin on the metabolism of glucose and lipid in diabetic patients.Methods:Retrieved randomized controlled trials(RCTs) on effects of Baduanjin on glucose and lipid metabolism in diabetic patients from PubMed, Web of Science, the Cochrane Library, Embase, CNKI with computer while mutually retrieved the same things from Chinese Clinical Trial Registry(ChiCTR), Google Academic and Baidu Academic. The retrieval time was from their establishment to October 2020. Then 2 researchers independently extracted relevant data and evaluated the quality of the included literatures, and meta-analysis was conducted on the included literatures using RevMan5.3.Results:This research used outcome indicators like fasting blood glucose, postprandial blood glucose, glycosylated hemoglobin, total cholesterol content and triglyceride content to explore the effect of Baduanjin on glucose and lipid metabolism in diabetic patients specifically.Conclusion:The research will provide reliable evidence-based proof for Baduanjin improving glucose and lipid metabolism of diabetic patients.Ethics and dissemination:Private information from individuals will not be published. This systematic review also does not involve endangering participant rights. Ethical approval was not required. The results may be published in a peer-reviewed journal or disseminated at relevant conferences.OSF Registration number:DOI 10.17605/ OSF.IO/AGJHQ.     

耳穴压豆联合八段锦对新型冠状病毒肺炎康复期患者焦虑抑郁的影响

目的探讨耳穴压豆联合八段锦对新型冠状病毒肺炎康复期患者焦虑、抑郁的影响。方法选取2020年2—4月在广州市第八人民医院6个隔离病区收治的康复期新型冠状病毒肺炎患者作为观察对象。按照随机数字法分为对照组、耳穴压豆组、耳穴压豆联合八段锦组,最终完成试验的分别为49例、48例、50例。对照组给予常规心理干预,耳穴压豆组在对照组的基础上给予耳穴压豆干预,观察组在对照组的基础上给予耳穴压豆联合八段锦干预。分别在干预前、干预2周末比较3组新型冠状病毒肺炎康复期患者焦虑和抑郁情况。结果干预2周末,3组均无重度焦虑或重度抑郁患者;干预2周末,耳穴压豆联合八段锦组新型冠状病毒肺炎康复期患者,其焦虑程度轻于对照组(χ²=23.673,P=0.003)和耳穴压豆组(χ²=18.708,P=0.029);干预2周末,耳穴压豆联合八段锦组新型冠状病毒肺炎康复期患者抑郁程度轻于耳穴压豆组(χ²=18.449,P=0.007)。结论常规心理干预,耳穴压豆及耳穴压豆联合八段锦3种治疗方案均能减轻新型冠状病毒肺炎康复期患者焦虑和抑郁程度,耳穴压豆联合八段锦在降低患者焦虑的程度要优于常规心理干预和单纯耳穴压豆。     

八段锦对2型糖尿病临床疗效Meta分析

目的:系统评价八段锦对2型糖尿病患者的临床治疗效果。方法:对中国知网、万方、维普、PubMed等4个数据库的文献进行检索,寻找与八段锦治疗2型糖尿病有关的随机对照实验的文献,检索范围设定数据库建库以来至2020年5月的所有中英文文献,事先设置好文献的检索词,并制定最终要纳入文献的标准以及文献的排除标准,使用Cochrane网提供的RevMan5.3软件进行分析。结果最终纳入符合标准的随机对照临床试验文献10篇,共有813例2型糖尿病患者,其中实验组406例,对照组407例。Meta分析显示:与常规治疗相比,加用八段锦治疗对于2型糖尿病患者的临床治疗效果更加显著,但受纳入研究文献的数量及质量影响,尚需要更多的临床证据。     

糖尿病前期中医药防治的临床科研探索与实践

糖尿病是人类慢性疾病中患病人数最多的疾病之一。目前早期糖尿病的诊疗管理只注重出现临床症状的患者,忽略了在发展成为糖尿之前这一阶段(糖尿病前期pre-diabetes)的诊疗管理在糖尿病的发生发展中所起的作用,从而使得流行病学调查的数据向我们展现了一个糖尿病患病人数持续高速增长的态势。作者认为,建立基于糖尿病前期患者的特定科研模式,以新的理论指导临床,以临床验证新的理论,有助于发展中医药治疗糖尿病前期的理论与创新,从而延缓糖尿病前期患者发展为糖尿病的趋势。论文通过对糖尿病前期的理论进行溯源,强调未病先防;通过糖尿病前期的临床诊疗探索实践,总结治方创新;分析糖尿病前期研究的热点问题,提出应对策略;以指南解读和全面筛查夯实基础,实施中医药早期干预等方面进行详细分析,对临床及科研对糖尿病前期中医药防治研究思路与方法有较高的指导意义。     

Effect of Baduanjin on physical functioning and balance in adults with mild-to-moderate intellectual disabilities: A comparative study

Background

Adults with intellectual disabilities often experience mobility limitations. Baduanjin, a mindfulness-based exercise intervention, can exert positive effects on functional mobility and balance. This study examined the impact of Baduanjin on physical functioning and balance of adults with intellectual disabilities.

Method

Twenty-nine adults with intellectual disabilities participated in the study. Eighteen received a Baduanjin intervention for 9-months; 11 participants did not receive any intervention (comparison group). Physical functioning and balance were assessed using the short physical performance battery (SPPB) and stabilometry.

Results

Participants in the Baduanjin group experienced significant changes in the SPPB walking test (p = .042), chair stand test (p = .015), and SPPB summary score (p = .010). No significant changes between groups were observed in any of the variables assessed at the end of the intervention.

Conclusions

Baduanjin practice may cause significant, albeit small, improvements in physical functioning of adults with intellectual disabilities.