A Multicentre Comparative Clinical Study of Three Types of IUD（Eight：Year Follow up）

The Stainless steel ring(SSR), VCu200 and TCu220C were in randomized comparison for eight years in a cohort of 4,490 subjects covering 16 centres in 9 provinces and municipalities. The follow-up rate at the end of the eithth year was 90.33%. The cumulative continuation rates were 47.06 per 100 women at the end of the eighth year for SSR,54.05 for VCu200 and 61.14 for TCu220C. The cumulative pregnancy rates for VCu200 and TCu220C were 10.35 and 8.94 per 100 women respectively, significantly lower than 24.14 for SSR. There were significant differences in eight-year expulsion rates among SSR(21.69%), VCu200(13.05%) and TCu220C(7.48%). The removal for bleeding and/or pain was the lowest in SSR; and no significant differences were found between VCu200 and TCu200C. but the rate ws getting higher in VCu200 at the end of the eighth year than in TCu220C. The discontinued use of lUD for desire to become pregnant in rural area was extremely higher than in urban area. The risk of pregnancy and expulsion was in association with the types of lUD in this study, age at insertion, previous use of IUD and pregnancy frequency prior to insertion. The risk of pregnancy and expulsion for VCu200 and TCu220C was significantly lower than that for SSR. Failure risks were associated with age at insertion, the types of IUD in this study and pregnancy frequency prior to insertion, and failure risk in SSR was still higher than in VCu200 and TCu220C at the end of the eighth year. The study revealed that TCu220C was of good long-term safe ty, efficacy, and acceptability.     

A Multicentre Comparative Clinical Study of Three Types of IUD （Eight－Year Follow up）

Ａ　ＭｕｌｔｉｃｅｎｔｒｅＣｏｍｐａｒａｔｉｖｅＣｌｉｎｉｃａｌＳｔｕｄｙｏｆＴｈｒｅｅＴｙｐｅｓｏｆＩＵＤ（Ｅｉｇｈｔ－ＹｅａｒＦｏｌｌｏｗｕｐ）ＦａｎｇＫｅ－ｊｕａｎ；ＣｈｅｎＪｕｎ－ｈａｎｇ；ＨｅＭｅｉ－ｌｉ；ＨａｎＹａｏ－ｌｉｎｇ；ＷｕＭｉｎ...     

动脉粥样硬化和胆石症异病同治的实验研究 Ⅰ.益气活血及疏肝理气对家兔动脉粥样硬化的影响

本实验比较观察益气活血及疏肝理气两类治则方药对家兔实验性高脂血症及动脉粥样硬化的影响,并从胆汁脂质成份、血浆LPO浓度、环核苷酸及TXA_2-PGI_2水平、血液流变学等指标探讨其机理。结果发现:(1)两类治则方药均有降血胆固醇、改善动脉粥样斑块的作用,且前方优于后方;(2)两类治则方药均能改变胆汁中脂质含量,减少胆石生成,但后方优于前方;(3)改善动脉粥样硬化的机理与降低血脂、降低LPO、提高cAMP/cGMP及改善TXB_2/6-KPGF_(1α)比值有关。实验提示不同方剂可因作用于相同发病环节而起到同病异治的作用。