多周期换热网络柔性综合与维护同步优化

提出柔性换热网络在初始设计阶段,考虑网络投入运行后,实施清洗维护时序安排的理论框架。通过柔性综合与维护同步优化,年度总费用能够进一步降低,同时网络柔性得到提高。为降低该NP难问题的计算复杂性,提出柔性换热网络初步综合和同步优化相结合的两阶段法。最后,通过计算实例验证了所提方法的有效性。     

重组艰难梭状芽孢杆菌毒素TcdB对人体肠上皮细胞层功能的影响

针对以往考虑污垢增长的柔性换热器网络(HEN)综合方法计算复杂、求解难度大等问题,提出了改进措施：首先简化由虚拟温焓图法得到的污垢热阻最大时的换热器网络结构,通过Excel中单变量求解函数对制约换热的因素进行调整来保证换热约束和降低总费用;然后应用遗传/模拟退火算法优化网络的换热面积。采用实例研究对该方法进行验证,结果表明：该方法在节省年度总费用的同时,有效地降低了计算复杂度,提高了计算效率。     

苯酚丙酮装置烃化单元能量系统优化

采用夹点技术对苯酚丙酮装置烃化单元进行了能量系统优化,计算确定现行换热网络有28.2%的节能潜力。通过对现行换热网络的夹点分析,找出了不合理的换热匹配。在现行换热网络已有结构特点和工艺要求的基础上,提出了换热网络优化改造方案。优化后烃化单元的换热网络可节省加热公用工程3 908.58 kW,投资回收期仅为3个月。     

基于改进蚁群算法的多目标Job-shop动态调度

实际作业车间调度中多目标的动态优化更符合生产的需求。利用多目标优化问题的Pareto解集思想构建最大完工时间最小以及总拖期时间最小的数学模型,以事件驱动作为动态调度策略实现作业车间的动态调度。采用多目标蚁群算法优化启发式算法,并对算法的转移概率及全局信息素更新进行改进,加快算法的搜索收敛速度同时避免陷入局部最优。仿真实验证明,改进后的算法能实现Pareto前沿较好的均匀性与分布性,对双目标调度以及单个目标独自调度时的甘特图对比,表明双目标优化算法能更好地平衡各个目标的解。最后对急件插入以及机器故障两种动态事件进行仿真,验证了改进蚁群算法在实际动态调度中有较好的实现。     

浅谈超临界CO2萃取工业化装置的设计制造

介绍了超临界CO2萃取技术的应用关键及超临界CO2萃取工业化装置的萃取釜、自动控制系统、换热系统、安全系统、在线检测等的设计与制造。     

基于改进量子粒子群算法的无分流换热网络综合

用数学规划法求解换热网络优化问题,当换热网络模型考虑所有分流情况时,会包含大量的连续和离散优化变量,因此对大规模换热网络的优化求解非常困难。相比有分流模型,无分流的网络模型结构简单,变量少,求解难度低。本文以分级超结构模型为基础,建立了无分流换热网络模型,以年综合费用为优化目标,提出用单层改进量子粒子群算法综合无分流换热网络,即在生成无分流换热网络结构变量的同时,生成换热负荷变量。相比有分流同步综合模型,不考虑分流的同步综合模型的复杂度和求解时间显著降低。采用两个典型算例对该方法的有效性进行了验证。     

一种求解阻塞流水车间多目标调度的离散差分进化算法

针对流水车间中产品不存在缓冲区的多目标优化问题,研究了阻塞流水车间的最大完工时间和总流程时间的最小化问题,提出了一种多目标离散差分进化（Multi-objective Discrete Differential Evolution,MDDE）算法搜索Pareto最优调度解。MDDE的变异个体通过非支配解或当前解的邻域随机产生,实验个体通过交叉操作产生,而选择过程则设计为一种多目标选择策略。此外,算法还混合了一种基于插入的Pareto局部搜索方法。基于标准测试算例的数值仿真实验表明,MDDE算法获得的非支配解集在Inverted Generational Distance、Set Coverage和Hypervolume性能指标上均有较好的表现。     

基于约束骨干粒子群算法的化工过程动态多目标优化

大多数化工过程是动态过程,需同时优化多个目标,从而带来复杂的约束多目标动态优化问题。因此提出了一种动态约束多目标骨干粒子群算法,即采用一种新型约束处理方法,结合Pareto支配和ε约束支配技术的双档集机制;针对约束优化问题寻优难度更大,更易陷入局部最优的特点,采用局部搜索和混合变异策略,并自适应调整搜索步长,提高算法的探索和开发能力;采用分段线性函数参数化方法,构建一种动态约束多目标粒优化算法,并将其用于解决间歇反应器的动态多目标优化问题。测试实验表明：与NSGA II和自适应差分进化算法(SADE εCD)比较,该算法具有更优秀的收敛性与分布性;应用到化工过程多目标动态优化问题实例进行比较表明,多目标骨干粒子群算法在约束多目标动态优化问题的求解中表现出更好的应用前景。     

基于支配度迁移模型的多目标生物地理学优化算法

针对传统多目标算法在解决MOPs问题时会出现Pareto前沿收敛结果不好、解集分布性不佳的情况,提出了基于支配度迁移模型的多目标生物地理学算法（MOBBO）。新的迁移模型充分利用了Pareto解之间的支配信息,有助于算法进行有效的个体评价和栖息地排序;为了强化算法的收敛效果,提出了基于优选特征库的自适应迁移策略,以便产生携带较好特征的候选解强化搜索能力;同时为了增强算法进化中Pareto解集的分布性,提出了改进的KNN密度估计方法淘汰过密的个体。通过ZDT和DTLZ系列测试函数以及MDI缩合过程的多目标问题优化上的比较,验证了MOBBO算法具有较快的收敛性和较好的分布延展性。     

基于动态扩张角的广义Pareto支配优化算法

NSGA-Ⅱ算法在处理高维多目标问题时解集的区分度变得很差,对此,有学者提出了基于扩张角的广义Pareto支配优化算法（GPO-NSGA-Ⅱ）,即通过改变扩张角来调整解的支配区域,从而调整解集的区分度,进化过程中扩张角保持恒定。本文在GPO-NSGA-Ⅱ算法的基础上提出了随着种群进化扩张角动态改变的广义Pareto支配优化算法（DGPO-NSGA-Ⅱ）,通过动态调整种群进化过程中的扩张角来影响种群进化的选择压。扩张角的动态调整采用线性减小方式,即随着种群的进化将扩张角从初始扩张角线性减小为0。为保证获得一个较好的初始扩张角区间,对种群进化的不同扩张角进行了大量对比实验。将该算法与GPO-NSGA-Ⅱ、NSGA-Ⅱ在测试函数上进行对比实验,结果表明该算法能以更高的精度更快地收敛到理论前沿,个体分布也更均匀。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.