自体皮片游离植皮术在难愈性创面治疗中的疗效观察

目的：观察自体皮片游离植皮术在难愈性创面中的应用效果和价值。方法：选择难愈性创面患者352例,经创面处理,基础病治疗,全身支持治疗,创面肉芽新鲜后,视创面部位行自体表层皮片联合中厚皮片游离植皮术,用烧伤敷料加压包扎。结果：352例患者,322例行一期清创植皮,30例行一期清创、二期植皮,其中340例植皮后超过90%皮片存活,创面愈合或接近愈合后出院,12例植皮后有小于1/3~1/2皮片未成活,经换药或补植后,创面愈合出院,平均住院时间（16±2） d,术后平均愈合时间（19±3） d。结论：自体皮片游离植皮术有助于难愈性创面愈合或提高存活率。     

负压封闭引流与传统加压包扎在四肢植皮术中的疗效比较

目的比较负压封闭引流与传统加压包扎法在四肢植皮术中的疗效。方法对2006年1月至2012年12月间因四肢损伤行植皮治疗的112例患者,随机分为应用VSD敷料结合半透膜覆盖固定皮片组(A组,52例)和应用传统加压包扎方法固定皮片组(B组,60例)。两组患者均于术后7天摘除敷料,从移植皮片成活率、创面感染率、皮下积血发生率、术后创面完全愈合时间等方面比较两种方法的疗效。结果移植皮片成活率A组(96.7±4.6)%、B组(92.5±6.7)%;创面感染:A组4例(7.69%)、B组19例(31.66%);皮下积血:A组0例、B组8例(13.33%);创面愈合时间A组(11.2±1.9)d、B组(12.7±2.9)d。两组间比较差异均有统计学意义(P<0.01),与应用传统打包加压包扎方法相比,应用封闭式负压引流术移植皮片成活率高,创面感染率、皮下积血发生率低,创面愈合快。结论在四肢植皮手术治疗中应用封闭式负压引流术固定皮瓣的疗效明显优于传统打包加压包扎法的疗效。     

37例大面积皮肤软组织缺损修复治疗分析

目的探讨创面封闭式负压引流(VSD)技术在皮肤软组织缺损修复应用。方法对收治的大面积的皮肤软组织缺损37例患者进行分析,20例进行传统治疗(清创、换药、培养肉芽)后进行二期手术行自体全厚游离皮片创面移植或邮票皮移植,12例创面愈合,6例经过多次换药后创面自行愈合,1例患者经过2次植皮治疗后,创面愈合。1例患者经过3次植皮治疗后,创面愈合。17例进行VSD后进行二期手术行自体全厚游离皮片创面移植或邮票皮移植,其中16例患者经过1次治疗后,创面愈合。1例经过多次换药后创面自行愈合。结果 VSD组住院天数、住院费用均较传统组减少(P<0.01)。结论 VSD是治疗大面积皮肤软组织缺损的较理想的方法之一,值得推广应用。     

自体网状皮移植联合生物敷料覆盖治疗混合度烧伤的临床观察

目的观察自体网状皮移植联合生物敷料覆盖治疗混合度烧伤的临床效果。方法将68例混合度烧伤患者分为两组。治疗组37例,采用自体网状皮移植联合生物敷料覆盖治疗;对照组31例,采用自体网状皮移植治疗。比较植皮面积/混合烧伤创面比例、术后换药次数、二次手术例数、创面愈合时间。结果治疗组植皮面积/混合烧伤创面比例、术后换药次数、二次手术率低于对照组,差异有统计学意义(P<0.05),两组创面愈合时间比较,差异无统计学意义(P>0.05)。结论自体网状皮移植联合生物敷料覆盖治疗混合度烧伤,能减少植皮面积,减少换药次数并避免换药痛苦,一期愈合率高,值得临床推广。     

封闭式负压吸引技术(VSD)治疗骨科创伤及感染创面的疗效及与常规换药的临床效果对比评价

目的对比评价封闭式负压吸引技术(VSD)治疗骨科创伤及感染创面的疗效及与常规换药的临床效果。方法现随机选取我院2017年3月至2019年3月收治的88例骨科创伤及感染创面患者,将所有患者根据入院顺序进行分组,将44例先入院的患者定为对照组,44例后入院的患者定为观察组,两组分别给予常规换药治疗和封闭式负压吸引技术(VSD)治疗,对比两组临床治疗效果。结果观察组患者治疗总有效率较高,其换药次数、创面愈合时间、住院时间及住院费用均较少,且患者发生的并发症较少,其数据结果同对照组患者数据相比差异较为明显(P0.05)。结论对骨科创伤及感染创面患者采取封闭式负压吸引技术治疗,可有效提高临床治疗效果,提高患者创面愈合速度,减少患者并发症发生,从而降低患者经济负担。     

负压封闭引流技术(VSD)在覆盖中小面积新鲜肉芽创面的对比研究

目的:分析负压封闭引流技术联合游离植皮在覆盖中小面积新鲜肉芽创面与普通游离植皮打包方法覆盖中小面积新鲜肉芽创面对植皮成活率无显著提高。方法:选择三组中小面积新鲜肉芽创面的患者各20例,A组采用普通清创游离移植中厚皮片,皮片表面不打引流孔,打包加压包扎,术后石膏托固定;B组采用普通清创游离移植中厚皮片,皮片表面打多个引流孔,打包加压包扎,术后石膏托固定。C组采用清创游离移植中厚皮片,皮片表面打多个引流孔,皮片表面放置VSD进行负压封闭引流,术后石膏托固定。所有患者术后应用抗生素1周,1周打开观察植皮成活情况。结果:A组植皮18例全部成活,1例边缘部分坏死,1例创面中心约1 cm2坏死;B组20例植皮全部成活;C组植皮17例全部成活,2例边缘部分坏死,1例成活欠佳,经过2周换药,创面愈合。结论:负压封闭引流技术(VSD)联合游离植皮在覆盖中小面积新鲜肉芽创面中对植皮成活率无显著提高。     

生物敷料加自体皮移植在小儿重度烧伤创面治疗中的应用

目的探究分析生物敷料加自体皮移植在小儿重度烧伤创面治疗中的应用效果。方法抽选本院儿科收治的重度烧伤患儿48例进行研究,入院时间均在2015年7月至2016年4月期间,进行简单随机分组,将其分为两组。对照组24例患儿接受直接自体皮移植治疗,观察组24例患儿则开展生物敷料加自体皮移植治疗,对两组患儿的创面愈合用时、植皮面积、术后换药次数以及非计划二次手术概率进行比较。结果观察组患儿创面愈合用时较对照组少,植皮面积小于对照组,术后换药次数少于对照组,其非计划二次手术概率亦低于对照组(P0.05)。结论生物敷料加自体皮移植治疗小儿重度烧伤创面的临床应用效果显著。     

自制简易封闭式负压吸引装置治疗小面积难愈性伤口

目的:探讨简易封闭式负压吸引装置治疗小面积难愈性伤口的疗效。方法:对54例小面积难愈性伤口清创后,分三组,每组18例,分别应用自制简易封闭式负压吸引装置,专业封闭式负压引流术(VAC)及传统换药处理伤口。待伤口肉芽形成后予皮瓣转移或刃厚皮片移植修复创面。结果:简易封闭式负压引流治疗组的患者经过6~15天治疗后,创面肉芽生长良好,经转移皮瓣或游离植皮成活。与传统换药技术相比,创面清洁时间明显缩短(P<0.05),达到专业VAC效果(P=0.647)。结论:简易封闭式负压吸引装置能有效控制渗液及感染,增加创面血运,可明显缩短肉芽形成及伤口愈合时间,减少换药次数,减轻医护人员工作量并降低医疗成本。     

封闭负压引流术联合扩创植皮术对大面积烧伤患者创面愈合效果的影响

目的:探究大面积烧伤患者采用封闭负压引流术联合扩创植皮术后创面愈合情况及并发症发生率。方法:选择2016年4月—2017年6月期间在我院治疗的56例大面积烧伤患者作为观察对象,随机将其分为观察组与对照组,每组28例。对照组行扩创植皮术与常规用药,观察组行封闭负压引流术联合扩创植皮术,比较两组创面愈合时间、创面愈合率、疼痛度评分及并发症。结果:观察组创面愈合时间短于对照组,创面愈合率高于对照组,VAS评分及并发症发生率低于对照组,差异有统计学意义(P <0. 05)。结论:在扩创植皮术与常规换药基础上加用封闭负压引流术,可有效提高大面积烧伤患者的创面愈合效果,减少感染,降低并发症。     

封闭式负压吸引技术在骨科创伤感染中的应用价值

目的:探讨封闭式负压吸引技术在骨科创伤感染中的应用效果.方法:选取我院收治的骨科创伤感染患者140例进行研究;按照随机数字表法进行分组,对照组70例,行常规换药治疗,观察组70例,采用封闭式负压吸引技术治疗,对2组的治疗效果进行比较.结果:观察组患者创面感染控制率明显高于对照组(P<0.05);创面感染愈合时间明显优于对照组(P<0.05);观察组患者换药次数、Ⅱ期手术时间、住院时间及抗感染费用均明显优于对照组(P<0.05).结论:封闭式负压吸引技术在控制骨科创伤感染、促进患者创面愈合、缩短患者住院时间方面均可发挥积极作用,可在临床上推广应用.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.