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1.
目的:观察无花果多糖对免疫抑制小鼠免疫功能的作用特点.方法:以氢化可的松所致免疫抑制小鼠为实验对象,连续7 d灌服无花果多糖,观察对小鼠腹腔巨噬细胞吞噬功能、溶血素及溶血空斑形成的影响.结果:无花果多糖可显著提高免疫抑制小鼠腹腔巨噬细胞的吞噬百分率和吞噬指数,显著促进溶血素形成、明显促进溶血空斑形成.结论:无花果多糖对氢化可的松致免疫抑制小鼠免疫功能有好的免疫促进作用.  相似文献   

2.
徐坤  苗明三 《中医学报》2011,26(3):324-325
目的:观察无花果多糖对免疫抑制小鼠免疫功能的作用特点.方法:以氢化可的松所致免疫抑制小鼠为实验对象,连续7 d灌服无花果多糖,观察对小鼠腹腔巨噬细胞吞噬功能、溶血素及溶血空斑形成的影响.结果:无花果多糖可显著提高免疫抑制小鼠腹腔巨噬细胞的吞噬百分率和吞噬指数,显著促进溶血素形成、明显促进溶血空斑形成.结论:无花果多糖对...  相似文献   

3.
目的:探讨无花果多糖对免疫抑制小鼠机体免疫功能的影响.方法:以环磷酰胺(Cyclophosphamide,CY)致免疫抑制小鼠为研究对象,观察无花果多糖对免疫抑制小鼠腹腔巨噬细胞吞噬功能、溶血素及溶血空斑形成和外周血淋巴细胞转化的影响.结果:腹腔注射CY可成功建立小鼠免疫抑制模型,大、小剂量无花果多糖组可显著提高免疫抑制小鼠腹腔巨噬细胞吞噬百分率及吞噬指数,可显著促进免疫抑制小鼠溶血素形成、明显促进溶血空斑形成,可显著提高免疫抑制小鼠外周血淋巴细胞转化百分率.结论:无花果多糖对CY所致小鼠免疫抑制有对抗作用.  相似文献   

4.
夏枯草多糖的体内免疫活性研究   总被引:1,自引:0,他引:1  
目的 研究夏枯草多糖对环磷酰胺所致免疫低下模型小鼠免疫功能的调节作用.方法 采用腹腔注射环磷酰胺(cyclophosphamide,CTX)复制免疫功能低下小鼠模型,并考察不同剂量夏枯草多糖对免疫抑制小鼠胸腺指数、脾脏指数、腹腔吞噬细胞吞噬功能、血清溶血素生成及溶血空斑形成的影响.结果 夏枯草多糖中、高剂量组能显著提高...  相似文献   

5.
目的:观察大枣多糖对氢化可的松致小鼠免疫抑制模型免疫功能的影响.方法:用氢化可的松腹腔注射所致的小鼠免疫抑制模型为实验对象,连续灌服大枣多糖7d,观察对小鼠免疫功能的影响.结果:大枣多糖可显著提高免疫抑制小鼠的腹腔巨噬细胞吞噬百分率和吞噬指数,显著促进免疫抑制小鼠溶血素和溶血空斑的形成.结论:大枣多糖能显著提高氢化可的...  相似文献   

6.
甘蔗渣多糖对免疫抑制小鼠免疫功能的影响   总被引:2,自引:0,他引:2       下载免费PDF全文
目的 观察甘蔗渣多糖对免疫抑制小鼠免疫功能的影响.方法 采用环磷酰胺(CY)造模法复制小鼠免疫抑制模型,测定甘草渣多糖对实验动物免疫器官重量指数、腹腔巨噬细胞的吞噬功能、迟发型变态反应(DTH)、溶血素(IgM)含量、溶血空斑形成、T细胞百分比和淋巴细胞转化.结果 小鼠灌胃剂量为200、400mg/(kg·d)的甘蔗渣多糖能显著提高免疫器官重量,增强小鼠巨噬细胞的吞噬功能,提高DTH和促进IgM、溶血空斑形成并且增加T细胞百分比和淋巴细胞转化率.结论 甘蔗渣多糖有显著提高免疫抑制小鼠免疫功能的作用.  相似文献   

7.
目的 探讨猫爪草多糖对环磷酰胺致小鼠免疫抑制模型免疫功能的作用特点。方法 应用环磷酰胺建立免疫抑制模型,观察大、中、小剂量猫爪草多糖对模型小鼠腹腔巨噬细胞吞噬功能、溶血素和溶血空斑形成以及淋巴细胞转化的影响。结果 大、中剂量猫爪草多糖可显著提高免疫抑制小鼠吞噬百分率和吞噬指数;中剂量猫爪草多糖和香菇多糖组可显著促进溶血素的形成;大、中、小剂量猫爪草多糖和香菇多糖均可显著促进溶血空斑的形成、促进淋巴细胞转化。结论 猫爪草多糖可明显改善环磷酰胺致免疫抑制小鼠免疫功能。  相似文献   

8.
百合多糖对小鼠免疫功能的影响   总被引:2,自引:0,他引:2  
弥曼  任利君  梅其炳  李汾  王多宁  刘绍国 《医学争鸣》2007,28(22):2034-2036
目的:观察百合多糖(LP)对小鼠免疫功能的影响.方法:环磷酰胺复制免疫抑制模型;测定胸腺、脾脏质量并计算脏器系数;鸡红细胞法测定单核巨噬细胞吞噬功能;绵羊红细胞法测定血清溶血素IgG,IgM含量;MTT法测定小鼠脾细胞的增殖.结果:在100~400mg/kg剂量范围内,LP可以提高免疫抑制模型小鼠的免疫器官指数,促进其吞噬指数和腹腔巨噬细胞增殖反应,提高其血清溶血素IgG,IgM含量;在75~150mg/L剂量范围内能促进小鼠脾细胞的增殖.结论:百合多糖能增强免疫抑制小鼠的非特异性和特异性免疫功能.  相似文献   

9.
黄剑林  周秦  王剑波 《医学争鸣》2009,(16):1494-1497
目的:优选桑叶多糖的水提取工艺和观察桑叶多糖对小鼠免疫功能的影响.方法:采用正交试验方法,对影响多糖的水提取工艺的因素水平进行了研究,并采用腹腔注射环磷酰胺造模,测定桑叶多糖对免疫功能低下小鼠炭粒廓清、巨噬细胞吞噬功能,血清溶血素效价(HC50)、抗体细胞形成数量(QHS值)及T,B淋巴细胞功能的影响.结果:桑叶多糖的最佳提取工艺为1:8倍量蒸馏水在80℃加热1.5h,回流提取1次;桑叶多糖能明显升高炭粒廓清k和a值以及HC50,QHS值(P〈0.05—0.01),提高巨噬细胞吞噬百分率、吞噬指数和T,B淋巴细胞功能(P〈0.01).结论:优选的桑叶多糖水提取工艺稳定可行,桑叶多糖具有增强小鼠免疫功能的作用.  相似文献   

10.
目的:利用化学与药理学相结合的方法,以药效学为指标,对猫爪草的免疫活性部位进行系统筛选。方法:以香菇多糖片作为阳性对照,对猫爪草的猫爪草多糖、石油醚提取部位、乙酸乙酯提取部位、乙醇提取部位的提取物采用正常小鼠,通过观察对小鼠腹腔巨噬细胞吞噬功能的影响、溶血素和溶血空斑形成的影响确定猫爪草的免疫活性部位,进行药理学筛选。结果:猫爪草多糖可使吞噬百分率、吞噬指数显著升高,可显著促进溶血素的形成。结论:猫爪草多糖为猫爪草的主要免疫活性部位。  相似文献   

11.
FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…  相似文献   

12.
CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.  相似文献   

13.
Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.  相似文献   

14.
OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.  相似文献   

15.
16.
Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P<0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.  相似文献   

17.
Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.  相似文献   

18.
In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.  相似文献   

19.
Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.  相似文献   

20.
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