电针中脘对阳虚体质任脉上浅表微循环血流灌注量的影响

目的:观察电针中脘穴对阳虚体质志愿者任脉线上能量代谢的影响,探讨电针调节作用与体质的关系。方法:对200名福建中医药大学在校大学生进行体质问卷,收集平和、阳虚体质志愿者各18例,应用激光多谱勒血流仪监测其常态下、电针中脘穴20min时,任脉上膻中、下脘及气海穴浅表微循环血流灌注量(microcirculatory blood perfusion units,MBPU)。结果:(1)在电针前,1阳虚体质组膻中、下脘、气海穴浅表微循环血流灌注量均低于平和体质组,其中膻中穴差异有统计学意义(P0.01),下脘、气海穴差异无统计学意义(均P0.05);2平和体质组3个穴位进行比较,膻中穴浅表MBPU高于下脘穴,但差异无统计学意义(P0.05);膻中、下脘穴浅表MBPU高于气海穴(均P0.01);3阳虚体质组3个穴位进行比较,膻中穴浅表MBPU低于下脘穴,高于气海穴(P0.05,P0.01);下脘穴浅表MBPU显著高于气海穴(P0.01)。(2)与电针前相比,两组受试者电针中脘20min时膻中、下脘、气海穴MBPU均显著升高(均P0.01)。(3)阳虚体质组电针中脘20min时膻中、气海穴微循环血流灌注量上升率高于平和体质组,但差异无统计学意义(均P0.05)。结论:阳虚体质志愿者任脉上能量代谢出现下降,尤以膻中穴明显;电针可通过调节机体经脉线上MBPU,升高平和、阳虚体质志愿者任脉上能量代谢。     

电针中脘对阴虚体质人群任脉上浅表微循环血流灌注量的影响

目的:探讨电针中脘穴对阴虚体质受试者任脉能量代谢的影响。方法:对200名福建中医药大学在校学生进行体质问卷,共收集到阴虚体质志愿者15例(女9例,男6例)。应用激光多普勒血流仪监测其常态下、电针中脘穴20 min、取针后10 min,任脉线上膻中穴、下脘穴及气海穴浅表微循环血流灌注量(MBPU)。结果:电针阴虚体质受试者中脘穴20min:1膻中穴浅表MBPU显著降低,与电针前比差异有统计学意义(P0.05);2下脘穴浅表MBPU较针前有所下降,但差异无统计学意义(P0.05);3气海穴浅表MBPU有所下降,与电针前比差异有统计学意义(P0.05)。与电针中脘穴20min相比,取针后10min3个穴位上浅表MBPU的改变均无统计学意义(P0.05)。结论:电针中脘穴能降低阴虚体质受试者任脉线上浅表MBPU,尤以膻中穴MBPU下降明显。     

电针命门对阳虚体质针刺反应时效的影响

目的:观察电针命门穴前后督脉线上循经红外辐射轨迹的变化,探讨平和体质、阳虚体质两种不同中医体质间的针刺反应时效差异。方法:选择受试者20例,采用Thermo Tracer TH9100型红外热像仪观察自然状态下电针命门穴20min期间、电针后10min红外热像图的变化。结果:(1)自然状态下,阳虚体质组受试者督脉循经红外辐射轨迹与周围组织分界较不明显且长度较短,平和体质组受试者督脉循经红外辐射轨迹连续性较好,与周围组织分界较明显且长度较长;(2)电针20min期间,各体质组督脉循经红外辐射轨迹由四周散在分布逐渐变为向后中线集中,并有增强趋势,但不同体质组间督脉循经红外辐射轨迹比较差异无统计学意义(P0.05);平和体质组针刺反应稳定时间点出现慢于阳虚体质组,差异具有统计学意义(P0.05)。结论:不同体质组督脉循经红外辐射轨迹差异与体质间气血阴阳状态相关;各体质组电针后督脉循经红外辐射轨迹均有变化,但针刺反应稳定时间点出现具有差异性,在一定意义上间接反映出针刺反应时效与体质的密切相关性。     

任脉循行线上红外辐射轨迹的加热诱发

目的探讨加热对人体任脉循经红外辐射轨迹的影响。方法以正常人体作为观察对象,对沿任脉显示的循经红外辐射轨迹进行观察,在此基础上,对自然状态下未能显示的循经红外辐射轨迹（infrared radiant trackalong meridian,IRRTM）的对象进行穴位、非穴位及非经对照点加热诱导,用Thermo Tracer TH9100型红外热像仪进行记录。结果多数受试者在任脉线上的穴位点或非穴位点加热都可以显著提高IRRTM的出现率,还可使已有的红外辐射轨迹距离增长,变得更加连续规整。而非经对照点一般不能诱发明显的IRRTM。加热诱发的效果受季节、受试者体形及加热时间的影响。结论加热对任脉循经红外辐射轨迹有明显的影响,加热经上穴位点与非穴位点既可诱发出所属经脉红外辐射轨迹,也可使既有的循经红外辐射轨迹变得更连续、规整。为进一步探讨循经红外辐射轨迹的形成机理及其相关的物质基础提供实验根据,也为临床灸疗和诊疗技术提供了直接和客观的依据。     

电针治疗肠黏膜损伤大鼠基本腧穴配伍“肠病方”的筛选

目的:选用临床治疗肠病最常用的3个腧穴即中脘、天枢、上巨虚,通过观察不同组合配伍的效应,选出最优的穴位组合。方法:SD大鼠126只,按随机数字表分为空白组、模型组、中脘组、天枢组、上巨虚组、中脘+上巨虚组、天枢+上巨虚组、中脘+天枢组、中脘+天枢+上巨虚组。采用8%冰乙酸灌肠法造模。各治疗组在相应穴位施以电针,每日1次,共治疗3次。治疗结束后,分别观察各组大鼠的结肠黏膜损伤指数、病理学损伤积分及超微结构变化。结果:与空白组相比,模型组结肠黏膜损伤指数显著降低(P<0.05),病理学损伤积分显著升高(P<0.05);7个电针组与模型组比较,结肠黏膜损伤指数显著升高(P<0.05),病理学损伤积分显著降低(P<0.05);天枢+中脘+上巨虚组与其它6个电针组相比,两项指标变化更显著(P<0.05)。超微结构观察表明,各电针组结肠黏膜损伤程度较模型组减轻,天枢+中脘+上巨虚组更加明显。结论:同时电针"中脘"天枢"上巨虚"减轻结肠黏膜损伤的作用优于其它单穴或双穴使用,因而可作为治疗肠病的基本处方。     

灸脐治疗寒凝血瘀型原发性痛经的临床疗效观察

目的探讨灸脐治疗寒凝血瘀型原发性痛经的临床疗效。方法运用石墨烯智能理疗仪对入选的20例原发性寒凝血瘀型痛经志愿者在非月经期进行灸脐治疗,比较治疗前后两周期行经期痛经症状,采集并分析灸脐治疗过程中任脉上经穴的体表红外温度变化情况。结果1、VAS视觉模拟评分,治疗后与治疗前数据比较,两者差异均有统计学意义(P<0.01),缓解痛经疼痛有效率60%;痛经症状积分,治疗后与治疗前数据比较,两者差异也有统计学意义(P<0.01);缓解痛经症状有效率70%。2、在灸脐过程中,任脉上穴位膻中穴、中脘穴、关元穴平均升温趋势最明显的时间段都出现在艾灸10-20 min内。结论1、石墨烯智能理疗仪治疗寒凝血瘀型原发性痛经具有一定疗效。2、石墨烯智能理疗仪灸脐治疗过程中任脉上穴位平均升温幅度在第10-20min最为显著。     

健康中年气郁体质人群体表红外热成像特征研究

目的:应用红外热成像的方法,观察健康中年气郁体质人群上半身及头面部共25个区域体表热值特征.方法:依据《中医体质分类与判定标准》,选择气郁质与平和质健康中年(45～59岁)人190例,其中气郁质组与平和质组各95例.运用红外热成像检测技术获得2组人群三焦、脏腑、督任脉及头面五官区域体表红外热值数据ΔT(ΔT=区域体表平均温度-躯干体表平均温度),并进行组内、组间统计学比较.结果:平和质组三焦ΔT比较差异无统计学意义(P>0.05),而气郁质组中焦、下焦ΔT显著低于上焦(P<0.05);2组督脉ΔT均显著高于任脉(P<0.05),而气郁质组偏离更大(P<0.05).与平和质组比较,气郁质组表现为:督脉热偏离(P<0.05);上焦热偏离(P<0.05),中焦及下焦凉偏离(P<0.05);躯干部胃脘、大腹、小腹、右少腹凉偏离(P<0.05),胸膺、虚里热偏离(P<0.05);头面部左额、右面颊凉偏离(P<0.05),鼻、唇热偏离(P<0.05).总体表现为8个区域呈现为凉偏离,6个区域呈现为热偏离.结论:气郁体质人群红外热图整体表现为上热下寒趋势,符合中年气郁体质人群气机郁滞、阴阳失衡的特点.     

任督脉循经感传在头面部交会现象的观察

目的 :观察头面部循经感传由督脉向任脉或由任脉向督脉的交会过程 ,其重点是观察感传绕过还是直接越过口裂。方法 :1 2名循经感传显著者 ,其中观察感传由督脉向任脉的交会过程 9例 :7例针刺位于督脉线上的奇穴印堂 ,2例针刺督脉经线印堂穴上 1寸 (经上非穴点 )。观察感传由任脉向督脉的交会过程 3例 ,其中 2例分别针刺光明穴和侠溪穴 ,另 1例先针刺印堂穴 ,随后针刺膻中穴 ,同时观察督脉与任脉的感传交接情况。结果 :所有受试者均出现循经感传由督脉绕口唇到达任脉或由任脉绕口唇到达督脉的交会过程。结论 :任督脉在头面部的交会过程是以绕过口唇的方式实现的 ,这与“环唇”、“别而络唇口”的历代文献记载相吻合。上述结果支持循经感传形成机理的外周观点     

电针治疗胃下垂176例疗效观察

山东中医学院附属医院针灸科,单纯采用电针治疗胃下垂176例。电针治疗方法,主穴:中脘、提胃穴、胃上穴、气海;配穴:足三里、内关。一般仅取主穴。中脘、提胃穴、胃上穴均呈45度向下斜刺,深度1～1.5寸;气海穴直刺1～1.5寸。用间动电疗机疏密波,负极接中脘穴,正极分五叉分别接双提胃穴、双胃上     

上脘、中脘、下脘穴的体表定位汇考与局部解剖探析

上脘、中脘、下脘穴为任脉上的三个重要腧穴,但历代医家对其体表定位的描述并不统一.现经查阅、比较古今文献记载的三穴的体表定位并结合现代解剖学知识对腧穴深层解剖结构的研究,明确了该三穴在不同解剖层次上的组织结构及其体内投影的脏腑器官,旨在为三穴的临床应用和针刺安全应用提供依据.     

运用fMRI观察电针关元及中脘穴相对特异性的脑功能网络

目的:比较电针关元和中脘穴激活的脑功能区及其功能区网络连接的异同。方法:21名健康志愿者参加电针关元穴、中脘穴时的fMRI配对试验,在针刺前静息状态、留针、电针(15 Hz,3次30 s,间以1 min)、拔针后静息态采集fMRI脑功能数据,并记录电针任务后的针感。采用t检验及卡方检验分析针感,SPM 2、短程和长程"中心度"法分析脑激活功能区及其之间的功能网络连接。结果:关元穴显示更强的胀满感。电针两穴均产生了额叶内侧部的明显负激活,留针及电针能改变脑静息默认功能模式,额叶内侧回、扣带前回前下部及海马区(脑边缘叶-旁边缘叶-新皮层系统)脑功能网络出现了明显的即时针刺后效应。两穴位脑效应存在较小的差异。结论:针刺关元、中脘穴均具有对脑边缘叶-旁边缘叶-新皮层网络的调制作用,但也存在较小的差异,显示了穴位脑效应相对特异性。     

针罐埋线与电针治疗胃肠实热型单纯性肥胖临床疗效对比

目的：寻找能够提高治疗胃肠实热型单纯性肥胖临床疗效的方法。方法：将82例胃肠实热型单纯性肥胖症患者随机分成A组（40例）、B组（42例）。A组采用电针加走罐、埋线法治疗；B组单纯采用电针治疗。两组电针取穴相同（中脘、下脘、气海等），A组除电针外在任、督、脾、胃、膀胱经脉走罐和穴位埋线。对其疗效、主要症状、体重指标、腰围、臀围和腰臀比值进行对比观察。结果：A组总有效率为90．0％，明显优于B组的78．6％（P〈0．01），在体重、体质指数（BMI）和腰围、臀围值下降方面，两组比较差异亦有显著性意义（P〈0．05，P〈0．01）；对消谷善饥、大便秘结、颜面痤疮等主要症状的改善方面，A组亦优于B组（P〈0．01）。结论：针罐埋线并用治疗胃肠实热型单纯性肥胖能提高疗效，是治疗本病较佳的方法。     

“益气调血,扶本培元”针刺法对正常老年人脑区葡萄糖代谢的影响

目的通过观察＂益气调血,扶本培元＂组穴对正常健康老年人脑葡萄糖代谢的影响,为针刺效应和特异性研究提供影像学依据。方法选择10例正常老年人随机分为穴位组和非穴组。治疗组取膻中、中脘、气海、血海、外关、足三里穴,对照组取上述穴位旁开的非经非穴点进行针刺研究,每天1次,每星期5次,连续进行8星期。治疗前和治疗8星期后所有患者均接受正电子发射型计算机断层显像（PET）脑功能成像检查,观察针刺前后感兴趣脑区葡萄糖代谢变化特征。结果针刺8星期后穴位组双侧额叶和双侧海马区葡萄糖代谢较针刺前均明显升高（P〈0.05）,非穴组针刺前后无明显变化;两组比较8星期后治疗组双侧额叶和左侧颞叶葡萄糖代谢均明显高于非穴组（P〈0.05）。结论 ＂益气调血,扶本培元＂组穴可以提高正常老年人认知相关脑区葡萄糖代谢,且具有显著的腧穴特异性。     

李延芳针灸“中气法”学术思想与临床应用

介绍李延芳老师针灸"中气法"取穴、刺法经验、治疗原理及治疗中风、不寐等病症的临床经验。该法针灸处方共选用上脘、中脘、建里、下脘、水分、肓俞、气海等7个腧穴为主,配合严格的操作手法和针刺深度,适用于临床多种病症的治疗。     

腹针配合美多巴治疗帕金森氏病临床观察

目的:探寻治疗帕金森氏病的有效疗法。方法:将60例患者随机分为腹针组(30例)和对照组(30例)。腹针组在服用美多巴的基础上加用腹针治疗,穴取中脘、下脘、气海、关元等;对照组单纯服用美多巴。结果:经过3个疗程治疗,腹针组的总有效率为90.0%,对照组为83.3%,两组相比,差异有显著性意义(P<0.05);腹针组副作用较对照组明显减少(P<0.05)。结论:腹针配合西药较单纯西药治疗原发性帕金森氏病能提高临床疗效,并能减少西药副作用。     

Pathologic analysis on hyperplasia of mammary gland with different syndromes based on infrared radiation temperature of acupoints

Objective

To explore the pathologic characteristics of hyperplasia of the mammary gland (HMG) by observing differences in infrared radiation temperature of points of HMG in patients with different syndromes compared with healthy controls.

Methods

A FLIR Systems Therma CAM™ P30 infrared thermal camera was used to detect the infrared temperature of Shanzhong (CV 17), Qimen (LR 14), Zhongwan (CV 12), Qihai (CV 6), Guanyuan (CV 4), Taixi (KI 3), and Taichong (LR 3) in 113 patients with HMG. Of these patients, 71 were placed in the Liver Qi stagnation group, 34 were placed in the Dysfunction of conception and thoroughfare vessels group, and 8 were placed in the Phlegm and blood stasis in combination group. The infrared radiation temperature of each point in the patients was compared with that of healthy controls, and the differences in the infrared radiation temperatures of the points in the patients were analyzed.

Results

Overall, the bilateral corresponding point in both the controls and patients exhibited no significant difference in infrared radiation temperature. In all cases, the infrared radiation temperature of the points from proximal to distal tended to decrease. In a comparison of the patients and controls, the infrared radiation temperature of the trunk points Shanzhong (CV 17), Qimen (LR 14), Zhongwan (CV 12), Qihai (CV 6), and Guanyuan (CV 4) of the patients was higher than that of the controls, while the infrared radiation temperature of the lower extremity points Taixi (KI 3) and Taichong (LR 3) was lower than that of the controls. Of these points, Shanzhong (CV 17) (P=0.0368), Zhongwan (CV 12) (P=0.0028), Qihai (CV 6) (P=0.0085), and Guanyuan (CV 4) (P=0.0018) showed significant differences. In a comparison of the corresponding point on the same side in the Liver Qi stagnation group and controls, the infrared radiation temperature of Shanzhong (CV 17) (P=0.0089), right-side Qimen (LR 14) (P=0.0382), Zhongwan (CV 12) (P= 0.0000), Qihai (CV 6) (P=0.0011), and Guanyuan (CV 4) (P=0.0000) of the patients was significantly higher than that of the controls, while the differences in the infrared radiation temperature of the other points were not statistically significant (P= 0.0833–0.8397). In a comparison of the corresponding point on the same side in the Dysfunction of conception and thoroughfare vessels group and controls, the infrared radiation temperature of left-side Taichong (LR 3) (P=0.0048), right-side Taichong (LR 3) (P=0.0329), left-side Taixi (KI 3) (P= 0.0171), and right-side Taixi (KI 3) (t=0.544, P= 0.0165) of the patients was significantly lower than that of the controls, while the differences in the infrared radiation temperature of the other points were not statistically significant (P=0.3793–0.9197). In a comparison of the corresponding point on the same side in the Phlegm and blood stasis in combination group and controls, the infrared radiation temperature of Shanzhong (CV 17), Qimen (LR 14), Qihai (CV 6), Guanyuan (CV 4), Taixi (KI 3), Taichong (LR 3), and Zhongwan (CV 12) tended to increase, but without statistical significance (P=0.175-.759).

Conclusion

The corresponding points of HMG patients with different syndromes are in different deficiency/excess states. Changes in the infrared radiation temperature of the trunk points Shanzhong (CV 17), Qimen (LR 14), Zhongwan (CV 12), Qihai (CV 6), and Guanyuan (CV 4) are closely related to the pathological characteristics of the Liver Qi stagnation syndrome of HMG patients, while changes in the infrared radiation temperature of the lower extremity points Taixi (KI 3) and Taichong (LR 3) are closely related to the pathological characteristics of the Dysfunction of conception and thoroughfare vessels syndrome of HMG patients. On the whole, HMG patients with Liver Qi stagnation syndrome are characterized by “upper excess,” and those with Dysfunction of conception and thoroughfare vessels syndrome are characterized by “lower deficiency.”     

针刺配合灸法治疗慢性疲劳综合征的临床随机对照研究

目的:观察、对比针刺法及针加灸法治疗慢性疲劳综合征(chronic fatigue syndrome,CFS)的临床疗效。方法:将133例CFS患者随机分为3组,即针刺组(n=47)、针加灸组(n=44)及非穴组(n=42)。针刺组予针刺百会、膻中、气海、关元、足三里、合谷、太冲、三阴交治疗;针加灸组予膻中、合谷、太冲、三阴交针刺治疗,百会、气海、关元、足三里温针灸治疗;非穴组在上两组所选腧穴周围1~2cm非腧穴点给予针刺。均留针30min,每日1次,10次为一疗程,共治疗2个疗程。应用Chalder疲劳量表和患者满意度自评量表对治疗后疲劳改善情况及治疗效果给予评估。结果:(1)疲劳积分改善情况:与治疗前比较,针刺组及针加灸组治疗后体力疲劳积分、脑力疲劳积分及疲劳总积分显著降低(P0.05,P0.01);与非穴组相比,治疗后针刺组及针加灸组上述3项指标显著降低(P0.05,P0.01);治疗后针加灸组的体力疲劳积分及疲劳总积分显著低于针刺组(P0.05)。(2)各组临床满意度比较:针加灸组满意率明显高于针刺组和非穴组(P0.05),而针刺组与非穴组相比差异无统计学意义(P0.05)。结论:无论单纯针刺法或温针灸法治疗CFS均具有良好的疗效,二者相比,又以温针灸法更优。     

Efficacy of moxibustion by stimulating acupoints of Danzhong(CV 17) and Ganshu(BL 18) on hyperplasia of mammary gland in rats

OBJECTIVE: To evaluate the efficacy of moxibustion, through stimulating acupoints of Danzhong(CV 17) and Ganshu(BL 18) in rats with hyperplasia of mammary gland(HMG) which induced by estrogen and progestogen.METHODS: Thirty female Sprague-Dawley rats were randomly divided into saline control group,HMG model group, and HMG moxibustion group with 10 in each group. Saline control was the group injected by saline. HMG model were created by injection of estrogen and progestogen. Moxibustion group was also injected of estrogen and progesto-gen with moxibustion at the same time. The Changes of nipple diameter and height were measured.The rats' skin temperature was recorded by an infrared thermal camera at the nipples, mammary areas,Danzhong(CV 17) and Ganshu(BL 18). Pathological changes of mammary gland in rats were also observed under light microscope.RESULTS: The diameter and height of the nipples in model group were prominently bigger and higher than that in control group(P 0.01). The diameter and height in moxibustion group were prominently smaller and lower than that in model group(P 0.01), and there was no significant difference between moxibustion group and control group.Compared with control group, skin temperature of the nipples, mammary area, and acupoints Danzhong(CV 17) and Ganshu(BL 18) decreased prominently in model group(P 0.01-0.05). Compared with model group, skin temperature of that in moxibustion group increased prominently(P 0.05).CONCLUSION: Treatment with moxibustion can effectively decrease the HMG rats' nipple diameter and height, and increase the skin temperature in HMG model rats at the nipples, mammary areas,Danzhong(CV 17) and Ganshu(BL 18). This study convinces the therapeutic effect of moxibustion on mammary gland hyperplasia.     

电针配合穴位埋线治疗心脾两虚型单纯性肥胖临床观察

目的:观察电针配合穴位埋线对心脾两虚型单纯性肥胖的干预效应.方法:将65例患者随机分为两组,观察组(33例)采用电针结合穴位埋线治疗,电针穴取中脘、下脘、关元、天枢等,穴位埋线穴取中脘、天枢、气海等;对照组(32例)单纯采用电针治疗.治疗前后进行体质量、体质量指数(BMI)、腰围、腰臀比(WHR)、匹兹堡睡眠质量指数(PSQI)、Hamilton焦虑量表(HAMA)、Hamilton抑郁量表(17项)(HAMD)评估,并与正常组35例对照.结果:观察组总有效率优于对照组(93.9% vs 84.4%,P＜0.05);单纯性肥胖患者体质量、BMI、腰围、WHR、HAMD、HAMA和PSQI均明显高于正常组(均P＜0.05);观察组和对照组治疗后,上述评分都有明显降低(均P＜0.05),且观察组改善更为显著(P＜0.05).结论:单纯性肥胖存在睡眠质量下降以及精神心理异常,电针配合穴位埋线在有效减肥的同时可提高睡眠质量和调整精神心理状态.