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1.
Objective To explore the relationship between retinal nerve fiber layer (RNFL) thickness and central corneal thickness (CCT) in myopia eyes.Methods 91 cases (91eyes) were selected from ophthalmological outpatients including 28cases with low myopia ( spherical equivalence [ SE ] > -3.0D), 33 cases with moderate myopia (SE -0.3D ~ -6.0D) and 30 cases with high myopia (SE < -6.0D).All patients received ocular standard examination including intraocular pressure, refraction, slitlamp biomicroscopy and fundus examination.Other ocular diseases except refractive error were excluded.RNFL thickness and CCT were measured by RTVue Fourior-OCT ( Optovue Inc, USA).Refraction diopter was shown as SE.Results The mean RNFL thickness and CCT was ( 108.5 ± 10.1 ) μm, (524.7 ±36.8)μm respectively.These were no significantly different among low, moderate and high myopia ( P > 0.05 ).Temporal RNFL thickness( tl1 ,tu1 ) was significantly positive related with CCT( r =0.281,0.093 of tl1, r= 0.352,0.167 of tu1 respectively in single and multiple variable analysis; P < 0.05 ), nasal ( nl2, nu2)and inferior nasal RNFL thickness( in2,in1 )was significantly positive related with SE( P <0.05), inferior temporal RNFL thickness( it2)was significantly negative related with SE( P <0.05), and RNFL thickness in other regions were not significant related with CCT and SE ( P > 0.05 ) in single and multiple variable regressive analysis.Conclusion Relationship between RNFL thickness of local paradisc region and CCT in myopia eyes suggested that CCT should be correlative with some sensible structural parameters in glaucomatous neuropathy and might be important in the diagnosis and therapy of glaucoma.  相似文献   

2.
目的 探讨近视眼患者视网膜神经纤维层(RNFL)厚度与中央角膜厚度(CCT)之间的关系.方法 选择91例眼科门诊近视患者(91眼),其中低度近视(等效球镜度数[SE]>-3.0D)28例(28眼),中度近视(SE-0.3D~-6.0D)33例(33眼),高度近视(SE<-6.0D)30例(30眼).均接受包括眼压、验光、裂隙灯、眼底等常规眼部检查,排除除屈光不正以外其他眼部疾病.利用RTVue Fourior OCT(Optovue Inc,USA)测量视盘周围RNFL厚度;利用CAM-L模块测量CCT.结果 近视眼患者RNFL厚度是(108.5±10.1)μm,CCT是(524.7±36.8)μm,在低中高近视组差异均无统计学意义(P>0.05).单因素相关及多元线性回归分析发现:颞侧(tl1,tu1)RNFL厚度与CCT呈正相关(tl1单因素及多因素r=0.281,0.093;tu1单因素及多因素r=0.352,0.163;P<0.05);鼻侧(nl2,nu2)和下方偏鼻侧(in2,in1)区域RNFL厚度与SE呈正相关(P<0.05);下方偏颞侧(it2)RNFL厚度与SE呈负相关(P<0.05);其他部位RNFL厚度与CCT、SE无相关(P>0.05).结论 近视眼视盘周围局部区域RNFL厚度与CCT存在相关性,表明中央角膜厚度与青光眼视神经病变敏感结构指标具有一定关系,对青光眼诊治具有重要指导意义.  相似文献   

3.
Objective To expore the clinical therapeutic effect of allergic rhinitis using endoscopic more nasal structures orthopedic surgery combined with steroid nasal spray. Methods Sixty allergic rhinitis patients accompanied by deviation of nasal septum, middle turbinate lesions, or/and inferior turbinate lesions, were divided into two groups: observation group with 30 cases, applying endoscopic more nasal structures orthopedic surgery combined with steroid nasal spray (mometasone furoate nasal spray) during perioperative period; control group with 30 patients, only applying steroid nasal spray (mometasone furoate nasal spray). Long-term effect was compared between two groups. Results Sixty cases were followed up for 1 year. The total effective rate was 90.0%(27/30) in observation group,22 cases of significant effect, 36.7% (11/30) in control group,3 cases of significant effect. The total effective rate had significant difference between two groups (P<0.01). Conclusion Using endoscopic more nasal structures orthopedic surgery combined with steroid nasal spray (mometasone furoate nasal spray) to treat allergic rhinitis has good long-term effect.  相似文献   

4.
Objective To investigate the changes of melatonin and cellular immunological function in children with febrile seizures and its clinical significance. Methods 50 children, including 23 cases with complex febrile seizure (CFS) and 27 cases with simple febrile seizure (SFS) , and 25 cases with upper respiratory infections children selected as control group were enrolled in this study. Serum melato- nin was measured by enzyme-linked immunosorbent assay (ELISA) and cellular immunological function was measured by flow eytomcter. Results The levels of serum melatonin in the 3 groups of CFS, SFS, control were(14. 91±2. 61) ng/L, (20. 72±2. 54) ng/L, (23.93± 2. Ol) ng/L, respectively. The melatonin levels in CFS children were significantly decreased than that in control group and SFS children (P <0. O1). CD3 + ,CD4 +, the ratio of CD4 + /CD8 + and CD8 + in CFS group were significantly decreased than that in control group and SFS group (P <0.01). The ratio of CD4 +/CD8 + in SFS group was significantly decreased than that in control group (P <0.05), but CD3 + ,CD4 + and CD8 + had no statistics significance among these groups(P >0. 05). The serum rnelatonin level were positive related withdecreaseddegreeofCD3+,CD4+ andtberatioofCD4+ /CDS+ (r≥0. 472, P <0.05). Conclusion The disorder cfcellular immunological function was possible related with the loss of serum melatonin, and the loss of serum melatonin maybe one of the reasons for febrile seizures relapse and brain injured.  相似文献   

5.
Objective To investigate the changes of melatonin and cellular immunological function in children with febrile seizures and its clinical significance. Methods 50 children, including 23 cases with complex febrile seizure (CFS) and 27 cases with simple febrile seizure (SFS) , and 25 cases with upper respiratory infections children selected as control group were enrolled in this study. Serum melato- nin was measured by enzyme-linked immunosorbent assay (ELISA) and cellular immunological function was measured by flow eytomcter. Results The levels of serum melatonin in the 3 groups of CFS, SFS, control were(14. 91±2. 61) ng/L, (20. 72±2. 54) ng/L, (23.93± 2. Ol) ng/L, respectively. The melatonin levels in CFS children were significantly decreased than that in control group and SFS children (P <0. O1). CD3 + ,CD4 +, the ratio of CD4 + /CD8 + and CD8 + in CFS group were significantly decreased than that in control group and SFS group (P <0.01). The ratio of CD4 +/CD8 + in SFS group was significantly decreased than that in control group (P <0.05), but CD3 + ,CD4 + and CD8 + had no statistics significance among these groups(P >0. 05). The serum rnelatonin level were positive related withdecreaseddegreeofCD3+,CD4+ andtberatioofCD4+ /CDS+ (r≥0. 472, P <0.05). Conclusion The disorder cfcellular immunological function was possible related with the loss of serum melatonin, and the loss of serum melatonin maybe one of the reasons for febrile seizures relapse and brain injured.  相似文献   

6.
Objective To investigate the changes of melatonin and cellular immunological function in children with febrile seizures and its clinical significance. Methods 50 children, including 23 cases with complex febrile seizure (CFS) and 27 cases with simple febrile seizure (SFS) , and 25 cases with upper respiratory infections children selected as control group were enrolled in this study. Serum melato- nin was measured by enzyme-linked immunosorbent assay (ELISA) and cellular immunological function was measured by flow eytomcter. Results The levels of serum melatonin in the 3 groups of CFS, SFS, control were(14. 91±2. 61) ng/L, (20. 72±2. 54) ng/L, (23.93± 2. Ol) ng/L, respectively. The melatonin levels in CFS children were significantly decreased than that in control group and SFS children (P <0. O1). CD3 + ,CD4 +, the ratio of CD4 + /CD8 + and CD8 + in CFS group were significantly decreased than that in control group and SFS group (P <0.01). The ratio of CD4 +/CD8 + in SFS group was significantly decreased than that in control group (P <0.05), but CD3 + ,CD4 + and CD8 + had no statistics significance among these groups(P >0. 05). The serum rnelatonin level were positive related withdecreaseddegreeofCD3+,CD4+ andtberatioofCD4+ /CDS+ (r≥0. 472, P <0.05). Conclusion The disorder cfcellular immunological function was possible related with the loss of serum melatonin, and the loss of serum melatonin maybe one of the reasons for febrile seizures relapse and brain injured.  相似文献   

7.
Objective To investigate the changes of melatonin and cellular immunological function in children with febrile seizures and its clinical significance. Methods 50 children, including 23 cases with complex febrile seizure (CFS) and 27 cases with simple febrile seizure (SFS) , and 25 cases with upper respiratory infections children selected as control group were enrolled in this study. Serum melato- nin was measured by enzyme-linked immunosorbent assay (ELISA) and cellular immunological function was measured by flow eytomcter. Results The levels of serum melatonin in the 3 groups of CFS, SFS, control were(14. 91±2. 61) ng/L, (20. 72±2. 54) ng/L, (23.93± 2. Ol) ng/L, respectively. The melatonin levels in CFS children were significantly decreased than that in control group and SFS children (P <0. O1). CD3 + ,CD4 +, the ratio of CD4 + /CD8 + and CD8 + in CFS group were significantly decreased than that in control group and SFS group (P <0.01). The ratio of CD4 +/CD8 + in SFS group was significantly decreased than that in control group (P <0.05), but CD3 + ,CD4 + and CD8 + had no statistics significance among these groups(P >0. 05). The serum rnelatonin level were positive related withdecreaseddegreeofCD3+,CD4+ andtberatioofCD4+ /CDS+ (r≥0. 472, P <0.05). Conclusion The disorder cfcellular immunological function was possible related with the loss of serum melatonin, and the loss of serum melatonin maybe one of the reasons for febrile seizures relapse and brain injured.  相似文献   

8.
Objective To investigate the changes of melatonin and cellular immunological function in children with febrile seizures and its clinical significance. Methods 50 children, including 23 cases with complex febrile seizure (CFS) and 27 cases with simple febrile seizure (SFS) , and 25 cases with upper respiratory infections children selected as control group were enrolled in this study. Serum melato- nin was measured by enzyme-linked immunosorbent assay (ELISA) and cellular immunological function was measured by flow eytomcter. Results The levels of serum melatonin in the 3 groups of CFS, SFS, control were(14. 91±2. 61) ng/L, (20. 72±2. 54) ng/L, (23.93± 2. Ol) ng/L, respectively. The melatonin levels in CFS children were significantly decreased than that in control group and SFS children (P <0. O1). CD3 + ,CD4 +, the ratio of CD4 + /CD8 + and CD8 + in CFS group were significantly decreased than that in control group and SFS group (P <0.01). The ratio of CD4 +/CD8 + in SFS group was significantly decreased than that in control group (P <0.05), but CD3 + ,CD4 + and CD8 + had no statistics significance among these groups(P >0. 05). The serum rnelatonin level were positive related withdecreaseddegreeofCD3+,CD4+ andtberatioofCD4+ /CDS+ (r≥0. 472, P <0.05). Conclusion The disorder cfcellular immunological function was possible related with the loss of serum melatonin, and the loss of serum melatonin maybe one of the reasons for febrile seizures relapse and brain injured.  相似文献   

9.
Objective To investigate the changes of melatonin and cellular immunological function in children with febrile seizures and its clinical significance. Methods 50 children, including 23 cases with complex febrile seizure (CFS) and 27 cases with simple febrile seizure (SFS) , and 25 cases with upper respiratory infections children selected as control group were enrolled in this study. Serum melato- nin was measured by enzyme-linked immunosorbent assay (ELISA) and cellular immunological function was measured by flow eytomcter. Results The levels of serum melatonin in the 3 groups of CFS, SFS, control were(14. 91±2. 61) ng/L, (20. 72±2. 54) ng/L, (23.93± 2. Ol) ng/L, respectively. The melatonin levels in CFS children were significantly decreased than that in control group and SFS children (P <0. O1). CD3 + ,CD4 +, the ratio of CD4 + /CD8 + and CD8 + in CFS group were significantly decreased than that in control group and SFS group (P <0.01). The ratio of CD4 +/CD8 + in SFS group was significantly decreased than that in control group (P <0.05), but CD3 + ,CD4 + and CD8 + had no statistics significance among these groups(P >0. 05). The serum rnelatonin level were positive related withdecreaseddegreeofCD3+,CD4+ andtberatioofCD4+ /CDS+ (r≥0. 472, P <0.05). Conclusion The disorder cfcellular immunological function was possible related with the loss of serum melatonin, and the loss of serum melatonin maybe one of the reasons for febrile seizures relapse and brain injured.  相似文献   

10.
Objective To investigate the changes of melatonin and cellular immunological function in children with febrile seizures and its clinical significance. Methods 50 children, including 23 cases with complex febrile seizure (CFS) and 27 cases with simple febrile seizure (SFS) , and 25 cases with upper respiratory infections children selected as control group were enrolled in this study. Serum melato- nin was measured by enzyme-linked immunosorbent assay (ELISA) and cellular immunological function was measured by flow eytomcter. Results The levels of serum melatonin in the 3 groups of CFS, SFS, control were(14. 91±2. 61) ng/L, (20. 72±2. 54) ng/L, (23.93± 2. Ol) ng/L, respectively. The melatonin levels in CFS children were significantly decreased than that in control group and SFS children (P <0. O1). CD3 + ,CD4 +, the ratio of CD4 + /CD8 + and CD8 + in CFS group were significantly decreased than that in control group and SFS group (P <0.01). The ratio of CD4 +/CD8 + in SFS group was significantly decreased than that in control group (P <0.05), but CD3 + ,CD4 + and CD8 + had no statistics significance among these groups(P >0. 05). The serum rnelatonin level were positive related withdecreaseddegreeofCD3+,CD4+ andtberatioofCD4+ /CDS+ (r≥0. 472, P <0.05). Conclusion The disorder cfcellular immunological function was possible related with the loss of serum melatonin, and the loss of serum melatonin maybe one of the reasons for febrile seizures relapse and brain injured.  相似文献   

11.
目的研究3岁以下婴幼儿胸腰椎椎弓根的解剖学特点,探讨椎弓根螺钉固定的可行性、安全性。方法收集中南大学湘雅二医院CT资料室内52例3岁以下婴幼儿的相关影像学数据,通过薄层密扫和三维重建技术分别在横断面、矢状面和冠状面对T1~L5椎弓根内径、椎弓根外径、椎弓根长度、椎弓根内倾角和椎弓根高度进行测量,总结婴幼儿胸腰椎椎弓根的解剖学特点。结果婴幼儿椎弓根直径最小的节段为T5或T6椎体,平均直径在3.0mm以下。椎弓根直径的整体变化趋势从T1至T5逐渐减小,帕至巧逐渐增大。年龄〈18个月儿童L4以上的平均椎弓根内径〈3.0mm,T3至19节段的平均椎弓根外径〈3.5mm。年龄18—36个月儿童巧至髓节段的平均椎弓根内径〈3.0mm,T4至T7节段的平均椎弓根外径〈3.5mm。椎弓根的直径、长度和高度与年龄呈明显正相关。结论18个月以下婴幼儿T3至,T9节段,18个月以上婴幼儿T4至T7节段的平椎弓根过于细小,置人椎弓根螺钉可行性低,风险较高。对3岁以下胸椎和腰椎疾患婴幼儿在T9节段以下进行椎弓根螺钉固定是可行、安全的。  相似文献   

12.
目的观察回肠血供,验证相应的手术对策,解决回肠造袋-肛管吻合术后肠道张力过高问题。方法解剖和观察45例回肠血管弓,从解剖学角度了解回肠血供机理及“延长”小肠的方法。结果血管弓2列者2例(4%),血管弓3列者35例(78%),四列者5例(11%),五列者3例(7%)。结论在右结肠动脉平面下,离断肠系膜上动静脉,松解了小肠长度50-60cm,尚有2。5列血管弓提供血液,可以避免回肠袋一肛管吻合术后肠管张力高和回肠缺血。  相似文献   

13.
孙琴洲  吉利  钟小龙 《中国医师杂志》2010,12(12):1628-1631
目的 探讨用Photoshop进行模型测量的可靠性.方法 牙列拥挤正畸病例上颌记存模10个,用数码相机分别拍摄其上下颌模型面的照片,用Photoshop法在数码相片上测量其前牙的可用间隙和必须间隙,用传统方法在石膏模型上测量其前牙的可用间隙和必须间隙,由5个测量者用同样的方法测量.比较不同测量者测量同一项目的 测量结果,以及同一测量者用两种测量方法的测量结果.结果 传统方法测量可用间隙时,5名测量者(M1~M5)的测量结果可重复性不高,M1的测量结果(44.87±2.55)mm分别与M3(42.15±2.20)mm和M5(41.86±3.12)mm的测量结果差异有统计学意义(P<0.05);Photoshop法测量可用间隙时,可重复性较传统方法高,M5的测量结果(41.10±2.96)mm和其余4人的测量结果差异皆有统计学意义(P<0.05);Photoshop法和传统方法测量必须间隙时,其可重复性皆比测量可用间隙时高,各组的测量结果差异无统计学意义(P>0.05).结论 测量必须间隙时,Photoshop法和传统方法差别不大,而测量可用间隙时,Photoshop法比传统方法有明显的优势.  相似文献   

14.
黄海 《中国医师杂志》2011,13(4):484-486
目的回顾内窥镜经鼻蝶手术入路发展,研究经蝶手术入路显微解剖,为内窥镜经蝶手术提供解剖学参考依据。方法采用20具成人尸体头颅,按经蝶手术人路方式解剖邻近血管神经,并进行显微解剖学观测,为临床内窥镜经蝶入路提供解剖学资料。结果对鞍底、蝶窦口、视神经、颈内动脉、垂体窝、海绵窦的结构构成及其邻近血管神经进行描述测量。结论熟悉蝶鞍区显微解剖结构有助于内窥镜经鼻蝶入路手术准确定位及术中安全操作。  相似文献   

15.
内镜下经鼻中下斜坡腹侧手术的应用解剖   总被引:1,自引:0,他引:1  
目的为内镜下经鼻中下斜坡腹侧手术提供解剖学依据。方法20具经10%福尔马林固定之完整成人头颅标本,解剖观察经鼻至中下斜坡手术入路的解剖学特点,确立手术标志,并测量与经鼻入路相关的解剖数据。新鲜完整头颅部标本5例,模拟手术。结果内镜经鼻颅颈交界手术的手术标志包括:中鼻甲、后鼻孔、咽鼓管咽口、鼻咽部黏膜、头长肌和颈长肌、咽结节、枕骨大孔前缘中点。经鼻入路完全暴露中下斜坡,最短距离为(89.60±2.52)mm;蝶窦前下壁和下斜坡磨除范围分别以两侧翼管和破裂孔为界,各自为距中线(9.37±0.59)mm和(10.75±0.63)mm。结论内镜经鼻入路可充分显露中下斜坡腹侧结构。  相似文献   

16.
目的 观察不同月龄雄性大鼠生化指标及颌骨、股骨骨形态计量的变化,探讨αD3对老年大鼠颌骨、股骨骨形态计量的影响.方法 将6周、6月及24月雄性wistar大鼠60只,分为四组.甲组:6周,15只;乙组:6个月,15只;丙组:24个月,15只;丁组:24个月+αD3组,15只.其中丁组按αD3 0.05 μg/(kg·d)溶于谷物油灌胃,隔天一次,每周3次,连续10周.颈总动脉取血测碱性磷酸酶(ALP)、酸性磷酸酶(Tracp5b)、骨钙素(BGP)、睾酮(T).取左侧颌骨、股骨测骨组织形态测量.结果 生化指标:(1)与6周相比,6月龄、24月龄、24月+αD3组ALP、BGP随月龄增长明显下降[(87.30±12.22)mmol/L VS(257.20±92.26)mmol/L,(55.23±18.18)mmol/L VS(257.20±92.26)mmol/L,(46.17±16.6)mmol/L VS(257.20±92.26 mmol/L);(4.37±1.46)ng/L VS(9.03±2.04)ng/L,(3.80±1.00)ng/L VS(9.03±2.04)ng/L,(3.59±0.64)ng/L VS(9.03±2.04)ng/L,P〈0.05];(2)与6月组相比,24个月及24个月+αD组TRACP5b随月龄增长明显增加[(15.69±1.62)pg/L VS(7.26±2.13)pg/L,(14.16±1.88)pg/L VS(7.26 ±2.13)Pg/L,P〈0.05];(3)T水平随月龄增长下降,但组间差异无统计学意义(P〉0.05).睾酮与颌骨松质骨面积呈正相关(r=0.52);(4)BGP与ALP呈正相关(r=0.58,P〈0.01),与.TRACPSb呈负相关(r=-0.49,P〈0.01).骨形态计量指标:(1)与6周组相比,24月龄、24月+αD3组股骨骨小梁面积明显增加[(220310.6±76360.50)μm2 VS(105093.5±73242.2)μm2,(293085.9±68230.78)μm2 VS(105093.5±73242.2)μm2,P〈0.05];(2)颌骨24月组较与6月组比较,骨小梁宽度增加53%,但骨小梁间隔增加123%;(3)24月+αD3组较24月龄颌骨骨小梁面积增加33%.结论 随月龄增长骨形成生化指标明显下降,骨吸收指标明显升高;睾酮与颌骨松质骨面积正相关;药物αD3有促进颌骨、股骨骨量的作用.  相似文献   

17.
目的探讨血清总前列腺特异抗原(tPSA)、血清游离PSA与总PSA比值(f/tPSA)、前列腺体积(PV)及前列腺特异抗原密度(PSAD)在早期前列腺癌(PCa)诊断中的价值。方法回顾性分析252例BPH患者和49例PCa患者的血清PSA值及相关检测结果。经直肠超声(TRUS)测定前列腺体积(PV),并计算f/tPSA和PSAD值。比较BPH和PCa组间血清tPSA、f/tPSA、PV和PSAD检测结果间的差异,分析这四项指标的ROC曲线下面积、诊断敏感性和诊断特异性的差异。结果PCa组患者tPSA、PSAD明显高于BPH组(P〈0.05),而f/tPSA、PV中PCa组患者明显低于BPH组(P〈0.01或P〈0.05)。ROC曲线下面积,血清tPSA(0.8013)、f/tPSA(0.7390)、PV(0.5613)三者检测诊断价值较低,PSAD(0.9214)值的检测诊断价值较前三者明显,即PSAD〉tPSA〉f/tPSA〉PV。当PSA取正常值高限4ng/ml时,诊断敏感性为91.49%,诊断特异性为51.05%,当f/tPSA取临界值0.16时,诊断敏感性57.78%,诊断特异性为78.72%,当PSAD取临界值0.15时,诊断敏感性88.24%,诊断特异性为81.52%。结论PSA、f/tPSA和PSAD都是前列腺癌早期诊断穿刺或随访的指标,提高前列腺癌的诊断敏感性和特异性,其中PSAD较PSA和f/tPSA具有更高的诊断价值。  相似文献   

18.
目的 从影像学角度探讨蝶鞍相关解剖对垂体腺瘤生长方式的潜在影响.方法 按照常用蝶窦分类方法,共收集83例蝶窦气化类型为全鞍型和20例鞍前型正常头颅的影像学资料;同时收集45例影像学提示为侵入蝶窦生长的垂体腺瘤临床资料进行分析.结果 (1)正常鞍底形态与蝶窦气化程度的关系:全鞍型蝶窦更易导致凹陷型鞍底(98.8%).(2)正常鞍底形态与垂体上缘形态的关系:凹陷型垂体上缘更易伴随凹陷型鞍底(93.8%).(3)根据正常头颅正中矢状位鞍窝骨性上口前后径与鞍窝前后最大径之间的关系,对蝶鞍形态提出初步分型:囊袋型、炒锅型、直筒型及筛型.(4)所有向蝶窦生长的垂体腺瘤患者蝶窦均为全鞍型.结论 鞍底形态、蝶窦气化程度及蝶鞍形态等综合因素能够解释垂体腺瘤向鞍底蝶窦生长的现象;结合文献,蝶鞍的相关形态学基础应该是影响垂体腺瘤生长方式的主要因素.  相似文献   

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