Poziotinib for EGFR exon 20-mutant NSCLC: Clinical efficacy,resistance mechanisms,and impact of insertion location on drug sensitivity

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Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy

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Toripalimab plus chemotherapy in treatment-naïve,advanced esophageal squamous cell carcinoma (JUPITER-06): A multi-center phase 3 trial

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Durvalumab with olaparib and paclitaxel for high-risk HER2-negative stage II/III breast cancer: Results from the adaptively randomized I-SPY2 trial

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Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis

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Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway

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MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells

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Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer

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KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer

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PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity

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Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis

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The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance

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Effect of ibrutinib with R-CHOP chemotherapy in genetic subtypes of DLBCL

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Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma

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Multi-omic analyses of changes in the tumor microenvironment of pancreatic adenocarcinoma following neoadjuvant treatment with anti-PD-1 therapy

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Signatures of plasticity,metastasis, and immunosuppression in an atlas of human small cell lung cancer

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Integrated multi-omics profiling yields a clinically relevant molecular classification for esophageal squamous cell carcinoma

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Neutrophil-activating therapy for the treatment of cancer

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The proteogenomic subtypes of acute myeloid leukemia

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Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling

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