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Poziotinib for EGFR exon 20-mutant NSCLC: Clinical efficacy,resistance mechanisms,and impact of insertion location on drug sensitivity
Institution:1. Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Unit 432, PO Box 301402, 1500 Holcombe Boulevard, Houston, TX 77030, USA;2. Department of Thoracic Imaging, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA;3. Department of Medicine, Johns Hopkins Sidney Kimmel Cancer Center, Baltimore, MD 21287, USA;4. Department of Dermatology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA;5. Institute for Applied Cancer Science, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA;6. Department of Biostatistics, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA;7. Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA
Abstract:
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  • Keywords:non-small cell lung carcinoma  epidermal growth factor receptor  exon 20 insertion
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