血清瘦素与绝经后2型糖尿病女性患者骨密度的相关性研究

目的探索血清瘦素与绝经后2型糖尿病患者骨密度的相关性。方法共纳入98名2型糖尿病女性进行分析,通过双能X线骨密度仪对受试者髋部BMD进行检查,并测定T评分,按照骨密度检测结果分为骨质疏松症组(PMOPW)以及非骨质疏松组(PMW)。对照组按照BMI与骨质疏松症受试者匹配。通过酶联免疫吸附法(ELISA)测定检测血清瘦素水平。结果两组血清瘦素和BMD值差异均有统计学意义(瘦素,(18.23±8.56) ng/m L vs (22.44±9.56) ng/m L,P0.05)和(BMD,(-0.74±0.13) vs(-3.127±0.55),P0.05)。在PMOPW中,血清瘦素和BMD与体重、BMI、腰围、臀围显著相关。多元线性逐步回归分析显示PMW和PMOPW的体重和BMI是BMD的独立预测因子。未发现血清瘦素水平是两组BMD的预测因子。结论体重和BMI对2型糖尿病患者BMD影响显著,但是未发现血清瘦素与PMW和PMOPW的BMD有关。     

骨硬化蛋白水平与绝经后妇女体脂含量及骨密度的相关性研究

目的 探讨绝经后妇女血清骨硬化蛋白水平与体脂含量及骨密度(bone mineral density, BMD)之间的相关性。方法 对230名年龄在50~75岁之间健康的绝经后妇女进行横断面研究。通过双能X射线吸收仪测量受试者全身、腰椎、左侧股骨BMD及全身脂肪和肌肉含量。通过定量夹心酶联免疫吸附法测量受试者血清骨硬化蛋白水平。结果 与非骨质疏松症的女性相比,骨质疏松女性血清硬化蛋白水平显著降低(P <0.05)。血清骨硬化蛋白水平与体重和脂肪量呈正相关(P <0.05)。即使在校正年龄、绝经年龄、身高和体重之后,骨硬化蛋白水平与全身及各个部位的BMD均呈正相关(P <0.05)。多元线性逐步回归分析显示,与年龄、绝经年龄、脂肪量和肌肉量相比,血清骨硬化蛋白水平是全身和腰椎BMD最重要的决定因素(P <0.05)。年龄与血清硬化蛋白对髋部BMD的影响相似。结论 在绝经后妇女中,骨质疏松症患者的血清硬化蛋白水平低于非骨质疏松症患者。血清硬化蛋白与全身、腰椎、髋部的BMD和体脂含量呈正相关。     

血清催产素浓度与绝经后女性骨密度相关性研究

目的探讨催产素与绝经后妇女骨代谢指标以及腰椎和髋部骨密度之间相关性。方法检测185例骨密度正常和132例患骨质疏松症女性的血清催产素、瘦素、雌激素和骨代谢指标浓度。腰椎和股骨颈的BMD通过双能X线吸收法测量。结果患骨质疏松症女性的血清催产素浓度低于骨密度正常的女性(P0.05)。骨质疏松症组中血清催产素浓度与年龄、绝经年限、体质量指数(body mass index,BMI)和血清PINP、BLAP和CTX浓度呈负相关;与瘦素和雌激素具有明显正相关性;在正常骨密度组中,血清催产素浓度和各种指标未发现明显的相关性。调整年龄和BMI后,腰椎和股骨颈骨密度仍然与绝经年限以及血清PINP、BLAP和CTX浓度呈负相关,与雌激素、瘦素和催产素浓度呈正相关。对年龄和BMI进行调整后,进行多元回归分析显示绝经年限、血清催产素、PINP和CTX是腰椎和股骨颈骨密度的显著预测因子。结论绝经后女性患者较高的血清催产素水平与较高的腰椎和股骨颈骨密度有关。     

血清锌、铜和脂质水平与绝经后妇女骨密度相关性研究

目的比较绝经后骨质疏松症女性和健康对照人群的血清锌(Zn)、铜(Cu)和血脂水平,并确定上述参数与骨密度(bone mineral density,BMD)之间是否存在关联。方法研究对象为116名绝经后妇女,包括58例骨质疏松症患者[骨质疏松组,年龄(58.9±3.7)岁]和58名对照者[健康对照组,年龄(55.1±1.9)岁]。使用原子吸收分光光度法测定血清锌和铜含量,通过双能X线骨密度仪检测所有女性腰椎(L1～4)和左侧股骨颈的骨密度。结果两组患者血清锌和铜含量相近(P0.05);骨质疏松组血清低密度脂蛋白(LDL)和总胆固醇(TC)水平与对照组相比差异有统计学意义(P0.05);相关分析显示体质量指数(bone mass index, BMI)与BMD值之间存在显著相关性(P0.05);血清Zn、Cu水平与血脂无显著相关性(P0.05);BMD与LDL(r=-0.302,P=0.002)和总胆固醇水平(r=-0.252,P=0.007)之间呈负相关。结论本研究表明血脂异常可能是绝经后妇女骨质疏松症的独立危险因素。此外,微量元素对BMD没有直接和相关的影响。     

血清神经肽Y水平与绝经后妇女骨密度相关性研究

目的探讨血清神经肽Y(NPY)水平与绝经后妇女骨密度(BMD)的相关性。方法纳入在我院门诊就诊的绝经后妇女。测量血清钙、磷、白蛋白、甲状旁腺激素(parathyroid hormone,PTH)、促甲状腺激素(thyrotropin,TSH)、25-OH维生素D和NPY浓度。根据骨密度检测结果将受试者分为3组,分别为BMD值:正常(n=66)、骨量减少(n=63)和骨质疏松症(n=63)。根据血清NPY水平,受试者也被分为3组:低NPY(n=30)、正常NPY(n=126)和高NPY(n=36)。结果骨密度正常、骨质疏松、骨质疏松症患者血清NPY、PTH和年龄水平差异有显著统计学意义(P<0.05)。对于不同的NPY水平,各组腰椎、股骨总、股骨颈、转子、股骨转子间和Ward’s三角BMD值有显著差异(P<0.05)。相关性分析显示血清NPY水平与患者年龄、BMI呈现显著正相关(P<0.05),与不同部位的BMD值之间均有显著负相关性(P<0.05)。结论血清NPY水平与患者年龄、体重指数或任何部位测量的BMD值之间有相关性。     

血清脂肪因子-CTRP3水平与绝经后妇女骨密度相关性研究

目的 观察血清脂肪因子-CTRP3水平与绝经后妇女骨密度的相关性。方法 选取2016年7月至2017年8月在我院就诊的192名绝经后女性,检测其CTRP3和骨钙素的血清水平。使用双能X线骨密度仪检测股骨颈和腰椎的骨密度(bone mineral density,BMD)。结果 骨质疏松患者血清CTRP3水平[(75.5±20.6) ng/mL]低于对照组[(88.7±21.8) ng/mL](P＜0.001)。同时,在血清CTRP3的三分位数中,骨质疏松症的频率显著降低(66.6％、53.4％和35.3％,P＜0.001)。此外,血清CTRP3与骨质疏松症风险较低相关[校正比值比=0.975,95％CI(0.962～0.987),P＜0.001]。最后,在所有参与者中,血清CTRP3水平与调整后股骨BMD(r=0.423,P＜0.001)、腰椎BMD(r=0.358,P＜0.001)和HDL-C(r=0.123,P=0.014)呈正相关。同时,CTRP3与HOMA-IR(r=-0.127,P=0.005)和胰岛素(r=-0.187,P＜0.001)呈负相关。结论 血清CTRP3水平降低与绝经后女性骨密度降低密切相关。     

血清视黄醇与绝经后妇女骨密度和骨代谢指标的相关 性研究

目的探讨血清视黄醇水平与绝经后妇女骨密度和骨代谢指标的相关性。方法对154例绝经后骨质疏松症妇女( 55岁)进行横断面研究,采用双能X线骨密度仪检测所有患者的骨密度(bone mineral density, BMD),同时检测患者的血清视黄醇、骨钙素、甲状旁腺素、碱性磷酸酶、钙和磷的水平,分析其相关性。结果 Spearman分析显示患者视黄醇水平与腰椎BMD (r=-0.161,P0.05)、股骨颈BMD (r=-0.181,P0.05)、碱性磷酸酶(r=0.109;P0.05)、磷(r=-0.109;P0.05)及生育时限(r=0.157;P0.05)呈正相关。经过多变量调整后,仍然发现血清视黄醇与腰椎(r=-0.209;P0.05)和股骨颈(r=-0.324,P0.05)的BMD呈负相关。结论血清视黄醇水平升高与低骨量的风险增加有关,因此,维生素A可能是骨质疏松症的危险因素之一。     

广东省女性绝经后原发性骨质疏松症调查分析

目的探讨广东省女性绝经后骨密度的变化规律及其影响因素相关分析。方法本研究通过对广东省50～87岁的1772名中老年人完成骨质疏松症问卷调查和进行双能X-ray骨密度测量。筛选绝经后原发性骨质疏松症患者274例,以5岁为1个年龄段,将其分成7个组。分析腰椎和髋部BMD值的变化规律。体重指数、脂肪含量与骨密度的关系。结果广东省不同城市女性原发性骨质疏松症患病率为11.1%～19.2%,总体患病率为15.5%。体重指数与髋部neck、Total骨密度相关系数(r=0.282,r=0.272,P<0.05),脂肪含量与腰椎正位Total骨密度相关系数(r=0.086,P<0.05)。结论广东省女性骨质疏松症患者腰椎骨密度在55～65岁和70～79岁两个年龄段丢失明显,髋部骨密度丢失在65岁以后下降速率加快。体重指数与髋部骨密度值有一定相关性,脂肪含量和腰椎骨密度值有较小相关性。     

血清羧化不全骨钙素对绝经后女性骨质疏松症诊疗意义的探讨

目的检测绝经后女性血清羧化不全骨钙素(ucOC)的水平,并探讨其影响因素及其对绝经后女性骨质疏松症诊疗的意义。方法选择南京医科大学附属南京医院2015年07月至2016年12月在骨科门诊就诊的绝经后女性患者108例,依据骨密度检查将这些患者分为骨质疏松组与非骨质疏松组;记录其年龄、身高、体重、体重指数(BMI)、绝经年龄、骨密度(BMD)等相关资料;抽取外周血测定碱性磷酸酶(ALP)、血钙、血磷、羧化不全骨钙素(ucOC)的水平,并对上述资料进行相关的统计学分析。结果绝经后女性骨质疏松组患者的血清ucOC水平与非骨质疏松组相比差异有统计学意义(P0.05);血清ucOC水平是骨质疏松症的影响因素(OR=2.806,P0.05)。(2)血清ucOC水平与腰椎骨密度呈负相关(r=-0.395,P0.05),但与髋关节骨密度无显著相关性(r=-0.248,P0.05)。结论血清ucOC水平的变化与绝经后女性骨质疏松症的发生关系密切,血清高ucOC水平是绝经后女性骨质疏松症发生的危险因素;推断血清ucOC水平对于绝经后女性骨质疏松症早期的预测和筛查具有参考意义     

血清Asprosin水平与绝经后女性骨密度、平衡能力和骨折发生率的相关性

目的探讨血清Asprosin(白脂素)水平与绝经后女性骨密度(bone mineral density,BMD)、平衡能力和骨折发生率的相关性。方法回顾性分析海南医学院第一附属医院收治的164例绝经后女性骨质疏松症(osteoporosis,OP)患者的临床资料。记录患者一般临床资料以及骨折发生率、髋部骨密度、平衡指数评分(BIS),前后比(FBR)和左右比例(RLR)。分析白脂素与BMD、BIS、FBR、RLR以及骨折发生率的相关性。结果非骨折组血清白脂素水平为(3.56±0.54)pg/mL,骨折组血清白脂素水平为(6.56±1.01)pg/mL,两组血清白脂素水平比较差异有统计学意义(P<0.05);Spearman试验结果显示,白脂素与BIS、FBR和RLR及BMD呈负相关(P<0.05);白脂素与年龄(r=0.384)、身高(r=0.343)、体质量指数(r=0.181)和髋部BMD显著相关(r=0.387),但与体重无显著相关性(r=0.022,P>0.05)。Logistic回归分析与线性回归分析显示,髋部BMD、身高、年龄和体质量指数是影响白脂素的独立因素。结论白脂素可能是绝经后女性出现骨密度降低和平衡能力下降及出现骨折的危险因子,与髋部BMD、身高、年龄和体质量指数密切相关。     

身高、体重及体重指数对辽宁地区正常中老年人骨矿含量的影响

目的　调查分析身高、体重及体重指数 (BMI)对辽宁地区正常中老年人群骨矿含量的影响。方法　在辽宁地区年龄在 40～ 79岁的中老年人群中随机抽样 173 1例 ,除外可能导致继发性骨质疏松症的各种疾病 ,应用美国lunar公司生产的双能X线骨密度仪 ,分别测试受试者的腰椎及股骨上段的骨密度 (BMD) ,全部资料输入微机 ,用SPSS软件进行统计学处理。结果　身高与腰椎及股骨上段的BMD相关性较差 (r=0 0 87～ 0 197,P <0 0 5 ) ,体重与腰椎及股骨上段的BMD相关性较好(r=0 2 2 6～ 0 3 5 2P <0 0 1)。体重指数与腰椎的相关性最好 ,其次是大转子。腰椎及股骨颈的BMD在超体重组 (BMI>2 5kg/m2 )明显大于低体重组 (BMI≤ 19kg/m2 ) ,其差异有显著性 ,该特点在腰椎最为明显。结论　体重是影响中老年人骨矿含量的重要因素。对低体重的中老年人 (BMI≤ 19kg/m2 )可作为骨质疏松症的易发人群 ,及时监测BMD ,早期预防及治疗     

DXA测定诊断骨质疏松症的敏感指标

目的探索双能X线吸收法（DXA）骨密度测定仪测定诊断骨质疏松症（OP）的敏感指标.方法随机抽取成都地区年龄20岁以上健康男、女1456名（其中女性793名）,准确测定身高（H）、体重（W）后,采用美国Lunar公司生产DPX-L型DXA测定受试者腰椎和髋部的骨矿含量（BMC）、骨密度（BMD）.全部资料输入微机,用SPSS软件进行统计学处理.结果男、女在峰值骨量后,随年龄增加,BMC、BMC/W、BMD均逐渐下降,BMC、BMD、BMC/W累积丢失率在40岁以上组均随年龄增加而增加,女性丢失更明显（P＜0.05）,同部位、同年龄组三指标累积丢失率差异无显著性（P＞0.05）.OP检出率以BMD为参照指标最高,明显高于BMC/W、BMC二指标（P＜0.05）.结论DXA测定中BMD能较好反应BMC、BMC/W变化,是诊断OP的敏感指标.     

体重、身高对成都地区青壮年腰椎、髋部骨量的影响

目的　研究体重、身高对青壮年腰椎、髋部骨量的影响。方法　随机抽取成都地区年龄在 2 0～ 39岁 ,排除心肝肺肾、内分泌等慢性病、骨代谢疾病及脊椎畸形者 2 37名 (其中男性 10 8名 ,女性 12 9名 ) ,采用美国Lunar公司生产DPX L型双能X线骨密度仪测定受试者腰椎和髋部的骨矿含量 (BMC)、面积 (AREA)、骨密度 (BMD)。全部资料输入微机 ,用SPSS软件进行统计学处理。结果　体重、身高、体重指数 (BMI)与腰椎、髋部的BMC、Area、BMD呈正相关 ,其中体重与腰椎、髋部的BMC、Area中等程度相关 (r=0 39～ 0 5 5 ,P <0 0 1) ,身高与腰椎 (L2 - 4)AREA相关性最好 (r=0 75 8,P <0 0 1) ,体重、身高与BMD相关性差 (r=0 15 2～ 0 2 2 5 ,P <0 0 5 )。男性腰椎及髋部的BMC、AREA均明显高于同年龄组女性 (P <0 0 1) ,男、女L2 - 4BMD无显著性差异 (P >0 0 5 ) ,男性略低于女性。L2 - 4BMC与体重比值及L2 - 4AREA与体重比值 ,男、女无显著性差异 (P >0 0 5 )。L2 - 4Area与身高比值男性明显高于女性 (P <0 0 1)。结论　体重对青壮年BMC的影响大于身高 ,身高对L2 - 4AREA影响最大 ,男、女体重、身高的差异决定了峰值骨量的差异。BMC、Area、BMD 3项指标中 ,BMC更能反映体重、身高的差异 ,用BMC诊断骨质疏松     

Peripheral Bone Mineral Density and Different Intensities of Physical Activity in Children 6–8 Years Old: The Copenhagen School Child Intervention Study

This study aimed to evaluate the association between objectively measured habitual physical activity and calcaneal and forearm bone mineral density (BMD, g/cm²), one mechanically more loaded and one less loaded skeletal region, in children aged 6–8 years. BMD was measured in 297 boys and 265 girls by peripheral dual-energy X-ray absorptiometry in the forearm and calcaneus. An accelerometer registered the level of physical activity during 4 days (2 weekdays and the weekend). Weight, height, and skinfold thickness were measured. In order to establish thresholds (count · min⁻¹) for bone-stimulating physical activity, we evaluated different definitions of vigorous physical activity. The boys had 3.2% higher distal forearm bone mineral content (BMC, P < 0.001) and 4.5% higher distal forearm BMD (P < 0.001) than the girls. They also carried out 9.7% more daily physical activity and spent 14.6–19.0% more time in vigorous physical activity (all P < 0.05) compared to the girls. In contrast, the girls had 3.8% higher calcaneal BMC (P < 0.01) and 2.5% higher calcaneal BMD (P < 0.05) than the boys. Both calcaneal and forearm BMD were significantly related to total time of daily physical activity as well as with intense physical activity above all the chosen cut-off points (all P < 0.05). The β value for mean count · min⁻¹ physical activity was significantly lower than that for all the chosen cut-off points of vigorous activity both for calcaneal and distal forearm BMD. This study suggests that both habitual daily physical activity and amount of vigorous physical activity in children aged 6–8 years are associated with appendicular BMD.     

The effects of first gestation and lactation on bone metabolism in dairy goats and milk sheep

The goal of the present study was to compare mobilization rate of calcium (Ca) from bone in pregnant and lactating goats and sheep. Blood samples were collected from goats and sheep monthly during pregnancy and at 1, 2, and 4 weeks postpartum (pp) and monthly during lactation until 6 months after parturition. Total bone mineral content (BMC) and total bone mineral density (BMD) were quantified using peripheral quantitative computed tomography at the same intervals as the blood was taken. Bone resorption was assessed by immunoassays quantitating two epitopes of the carboxyterminal telopeptide of type I collagen (ICTP, CTX). Bone formation was estimated by quantifying serum osteocalcin (OC) and bone-specific alkaline phosphatase (bAP). In addition, Ca and 1,25-dihydroxy vitamin D (1,25-VITD) concentrations were determined in serum.

Mean ICTP and CTX concentrations of both animal species increased the first week after parturition. By the second week pp, the concentrations of both markers had decreased toward early gestation levels. In contrast, mean OC concentrations continually decreased until the 1st week pp. By the 2nd week pp, the mean concentrations of OC started to increase again. Mean bAP activities decreased during gestation and reached a nadir in the first week pp in goats and 4 weeks pp in sheep. Afterwards, mean bAP activities increased again in goats and sheep. 1,25-VITD concentrations peaked the first week pp and returned to early gestation values thereafter. Total BMC and BMD decreased from the 4th month of pregnancy until the 1st week pp in both species. Afterwards, BMC increased throughout the first month pp in goats and the first 3 months pp in sheep. BMD levels of sheep and goats returned to prepartum levels during lactation.

The resorptive phase of bone remodeling is accelerated at parturition and in early lactation and is uncoupled from the process of bone formation. This allows the animal to achieve Ca homeostasis at the expense of bone. Increased bone remodeling during lactation may represent physiological mechanisms to help replace the maternal skeleton lost as the animal adapted to enormously increased Ca losses to the fetus and milk in late gestation and early lactation.     

Normalization of bone mineral content to height,weight, and lean body mass: Implications for clinical use

Summary The main object of the present study was to reduce the large biological variation in forearm bone mineral content (BMC) by correction for individual variation in gross morphology. In 315 normal females aged 45–54 years, determinations of height, weight, and 24-h urinary creatinine excretion rates were performed, and lean body mass was calculated. BMC was measured by photon absorptiometry on both forearms. BMC was correlated to height (r=0.19,P<0.01), to weight (r=0.09,P>0.05), to lean body mass (r=0.15,P<0.05), and to creatinine excretion rate (r=0.29,P<0.001). The biological variation in BMC of the 315 females was for raw BMC 15.8%; after correction of BMC for height 15.5%, for weight 15.8%, for lean body mass 15.6%, and for creatinine excretion rate 15.2%. Regression analysis with two independent variables (creatinine excretion and height or weight) increased in both cases the correlation coefficient to 0.32 and decreased the interindividual coefficient of variation of BMC to 15.0%. For diagnostic purposes BMC must be corrected for age and sex, but further corrections seem of minimal benefit.     

中国男女性骨大小和体积骨密度的探讨

目的　确定中国北方人群在腰椎和股骨部位峰值骨大小和体密度的性别差异 ,并分析影响其大小的因子。方法　年龄 15至 4 0岁 2 5 6例健康男性和 30 9例健康女性 ,他们的腰椎和股骨颈的骨大小和体积骨密度用双能X线骨密度仪测量。椎体和股骨颈近似为圆柱体 ,骨体积V =π× (宽度 2 ) 2 ×高度 ,vBMD =BMC 体积。结果　椎体峰值BMC ,体积和vBMD女性在 30～ 4 0岁达到峰值 ,而男性 15～ 17岁达到峰值。椎体和股骨颈的BMC男性比女性高 18 1%～ 2 6 7% ,而骨体积相应高 2 8 5 %～ 32 0 % ,这样vBMD男性比女性低 4 0 %～ 8 3% (P <0 0 1)。初潮较晚 (≥ 15岁 )绝经前妇女比来潮较早者 (≤ 12岁 ) ,BMC低 10 % (P <0 0 5 )。男性抽烟者与非抽烟者骨大小和vBMD没有统计学差异。饮酒也没有观察到明显的效应。结论　中国男性比女性有较低的vBMD ,这可能部分地解释中国男性有较高骨折发生率的原因     

Precision of dual-photon absorptiometry

Summary Precision of dual-photon absorptiometry (DPA) measurements was determined in a lumbar spine phantom and in humans. Approximately half of the measurements were made before and half after a¹⁵³gadolinium source change. The phantom was measured with different amounts of acrylic, which simulates human soft tissue, in order to evaluate the influence of body thickness on bone mineral density (BMD). Results of scans analyzed with two software versions from Lunar Radiation Corp., the widely used 08B and a prototype 08C, are compared. DPA with a cold source significantly overestimated BMD in the phantom in the presence of large amounts (more than 25 cm) of soft tissue equivalent with version 08B but not with the newer version 08C. Similiarly, in nine subjects, there was a significant decrease in spine BMD after a source change when scans were analyzed with version 08B (mean difference 0.026 g/cm²,P=0.002) but not with 08C (0.01 g/cm²,P=0.234). No systematic effect of source change on femoral BMD measurements was observed. The SD of the mean difference of two measurements of the nine subjects was 0.019 g/cm² (1.6% of the mean value) for the spine with software version 08B and 0.024 g/cm² (2.0%) with version 08C, 0.03 g/cm² (3.3%) for the femur neck, 0.03 g/cm² (4.0%) for the greater trochanter, and 0.04 g/cm² (4.9%) for Ward's triangle region of the proximal femur. The spine phanton was scanned on two other commercial bone densitometers in order to assess inter-instrument variation. Phantom measurements of L2-4 BMD made on two Lunar Radiation Corp model DP3 scanners which differed by 2% were 10 and 12% higher than those with a Norland Corp. model 2600 scanner.     

Relationship between leg bone mineral values and muscle strength in women with different physical activity

This study examines whether knee extensor muscle isometric, isokinetic, and isoinertial strength values in women with different physical activity and body composition patterns are related to leg bone mineral density (BMD) and bone mineral content (BMC) values. A total of 129 women aged 17–40 participated in this study. They were divided into four groups: strength-trained (n = 33), endurance-trained (n = 32), normal weight sedentary (n = 41), and overweight sedentary (n = 23) women. In addition, the subjects were grouped as physically active (n = 65) or sedentary (n = 64) women. BMD and BMC for both legs (LBMD and LBMC, respectively) and for the dominant leg alone (DLBMC), body fat percentage and lean body mass (LBM), maximal knee extension isometric (ISOM) and isokinetic (ISOK) strength at the angular velocity of 60 deg·s⁻¹, and isoinertial leg explosive strengths (countermovement jump CMJ) were measured. In endurance-trained women, LBMD was dependent on body mass index (BMI) (33.7% of the variance, R² × 100), and in the physically active group and the total group with LBM (14.6% and 15.6%, respectively). In the overweight group, LBMD was dependent on ISOK strength (21.7% of the variance, R² × 100). In the sedentary and total groups, ISOM strength was more important (10.3% and 5.0%, respectively); in the strength-trained group, body weight influenced LBMC, accounting for 71.6% of the variance (R² × 100). In the endurance-trained women, height influenced LMBC (37.9%, R² × 100). In sedentary and overweight women, LBM accounted for 52.1% and 61.4% of the total variance in LBMC. In these groups, ISOM strength accounted for 15.3% and 25.9% of the variance in LBMC. In overweight women, ISOM and ISOK strength together influenced LBMC highly (64.8% of the variance, R² × 100). In the sedentary group, the influence of LBM on LBMC was higher than in the active group (82.1% and 50.5% of the variance, respectively). In the total group, LBM influenced LBMC, accounting for 54.5% of the variance (R² × 100). ISOM strength (22.7%) alone or in combination with ISOK strength (35.8%) and CMJ (41.7%) (R² × 100) in LBMC in the sedentary group explained the variance. In the total group, ISOM strength alone (13.2%) or in combination with CMJ (17.1%) influenced LBMC (R² × 100). Our results suggest that (1) muscle strength and anthropometrical parameters were associated with LBMD; (2) LBM and ISOM strength had a significant relationship with DLBMC and LBMC only in nonathletic women; and (3) strength measured with different regimens highly influenced LBMC compared with LBMD, especially in the sedentary groups.     

骨质疏松症患者的牙周组织检查

骨质疏松症和牙周炎均为中老年人的多发病，并都有骨的吸收破坏，骨量减少。为了阐明两者的关系，本研究对２９例中重度骨质疏松症患者和２５例骨密度正常者的牙周状况进行了检查与对比。结果表明：骨质疏松症患者和骨密度正常者的牙周炎患病率无明显差别，表明骨质疏松症与牙周炎之间无明显的相关关系。根据本研究结果提示：骨质疏松症在牙周炎的发生上并不起主要作用，局部（菌斑诱导的非特异性炎症）因素比全身因素在牙周炎的发病机理中更为重要。