Transient Inhibition of PI3Kδ Enhances the Therapeutic Effect of Intravenous Delivery of Oncolytic Vaccinia Virus

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CRISPR base editing of cis-regulatory elements enables the perturbation of neurodegeneration-linked genes

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Reprogramming of the heavy-chain CDR3 regions of a human antibody repertoire

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Rescue of auditory function by a single administration of AAV-TMPRSS3 gene therapy in aged mice of human recessive deafness DFNB8

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Inhibition of lncRNA MAAT Controls Multiple Types of Muscle Atrophy by cis- and trans-Regulatory Actions

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Intercellular transfer of miR-200c-3p impairs the angiogenic capacity of cardiac endothelial cells

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Extracellular vesicle-based delivery of silencing sequences for the treatment of Machado-Joseph disease/spinocerebellar ataxia type 3

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Modulation of NLRP3 inflammasomes activation contributes to improved survival and function of mesenchymal stromal cell spheroids

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Isoforms of MUC16 activate oncogenic signaling through EGF receptors to enhance the progression of pancreatic cancer

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Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry

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Targeted In Vivo Delivery of NF-κB Decoy Inhibitor Augments Sensitivity of B Cell Lymphoma to Therapy

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Current Status and Challenges of DNA Base Editing Tools

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Antitumor activity of a lectibody targeting cancer-associated high-mannose glycans

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Development of a double shmiR lentivirus effectively targeting both BCL11A and ZNF410 for enhanced induction of fetal hemoglobin to treat β-hemoglobinopathies

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Prognostic Impact of Right Ventricular Strain in Isolated Severe Tricuspid Regurgitation

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Passive immunization against phosphorylated tau improves features of Huntington's disease pathology

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Increasing the Specificity of AAV-Based Gene Editing through Self-Targeting and Short-Promoter Strategies

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Prevalence of Right Atrial Impairment and Association with Outcomes in Cardiac Amyloidosis

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Neuropeptide Y attenuates cardiac remodeling and deterioration of function following myocardial infarction

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The emerging regulatory roles of long non-coding RNAs implicated in cancer metabolism

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