The evolgate: a method to improve the pullout strength of interference screws in tibial fixation of anterior cruciate ligament reconstruction with doubled gracilis and semitendinosus tendons

Purpose:The goal of the study was to investigate the biomechanical properties of a new device for tibial fixation in arthroscopic anterior cruciate ligament reconstruction using doubled semitendinosus and gracilis tendons.Type of Study:Biomechanical study.Methods:This study compares the initial pullout strength, stiffness, and failure modes of 7 pairs of 4-strand human semitendinosus and gracilis grafts fixed to porcine tibias using either the Evolgate (Citieffe, Bologna, Italy) or 1 round threaded titanium interference screw. Structural tests of the graft fixation method tibia complexes were performed using a materials testing machine (MTS Bionix 855, Minneapolis, MN) at a strain rate of 50 mm/second.Results:The mean failure load was 1,237 ± 191 N for the Evolgate and 537 ± 65 N for the interference screw (P < .05) and the mean stiffness was 168 ± 37 N/m for the Evolgate and 105 ± 17 N/m for the interference screws (P ≤ .05). Although in all the cases fixed with the Evolgate failure occurred because of tendon rupture inside the tibial tunnel close to the fixation device, in 4 of the 7 cases fixed with interference screws, failure occurred because of tendon slippage at the fixation site.Conclusions:These results indicate that initial pullout strength of hamstring tendon graft interference screw fixation can be significantly increased using the Evolgate. In fact, because the screws purchase only in the cancellous bone, the Evolgate reinforces the walls of the tibial tunnel with a titanium involute, avoiding the loss of fixation strength related to the low density of the cancellous bone of the proximal metaphysis of the tibia.     

Biomechanical evaluation of patellar- and hamstring tendon graft fixation for anterior cruciat ligament reconstruction using a poly-(D, L-lactide) interference screw

Anterior cruciate ligament (ACL) reconstruction using autologous hamstring tendons are being performed more frequently and satisfactory results have been reported. Advantages such as low donor site morbidity and ease of harvest as well as disadvantages like low initial construct stiffness have been described. Recently, it has been demonstrated that graft fixation close to the original ACL insertion sites increases anterior knee stability and graft isometry. Hamstring tendon fixation techniques using interference screws offer this possibility. To reduce the risk of graft laceration, a round threaded titanium interference screw (RCI) was developed. To improve initial fixation strength, fixation techniques for hamstring tendons with separate or attached tibial bone plugs were introduced. However, data on fixation strength do not yet exist. With respect to the proposed advantages of biodegradable implants, like undistorted magnetic resonance imaging, uncompromised revision surgery and a decreased potential of graft laceration during screw insertion, we performed pullout tests of round threaded biodegradable and round threaded titanium interference screw fixation of semitendinosus (ST) grafts with and without distally attached tibial bone plugs. Data were compared with bone-tendon-bone (BTB) graft fixation using biodegradable and conventional titanium interference screws. We used 56 proximal calf tibiae to compare maximum pullout force, screw insertion torque, and stiffness of fixation for biodegradable direct ST tendon and bone plug fixation (group I: without bone plug, group II: with bone plug) versus titanium interference screw fixation (group III: without bone plug, group IV: with bone plug). A round threaded biodegradable poly-(D, L-lactide) (Sysorb) and a round threaded titanium interference screw (RCI) were used. As a control calf bone-tendon-bone (BTB) grafts fixed with either poly-(D, L-lactide) (group V) or conventional titanium (group VI) interference screws were used. ST tendons were harvested either with or without their distally attached tibial bone plugs from human cadavers and were folded to a three-stranded graft. Specimen were loaded in a material testing machine with the applied load parallel to the long axis of the bone tunnel. Maximum pullout force of ST bone plug (group III: 717 N +/- 90, group IV: 602 N +/- 117) fixation was significantly higher than that of direct tendon (group I: 507 N +/- 93, group III: 419 N +/- 77) fixation. Maximum pullout force of biodegradable screw ST fixation was higher than that of titanium screw fixation in both settings. There was no significant difference in pullout force between biodegradable (713 N +/- 210) and titanium (822 N +/- 130) BTB graft fixation or between ST fixation with bone plug and biodegradable screw with BTB fixation. Pullout force of hamstring tendon interference screw fixation can be improved by using a biodegradable implant. In addition, initial pullout force can be greatly improved by harvesting the hamstring tendon graft with its distally attached tibial bone plug. This may be important, especially in improving tibial graft fixation. This study encourages further research in tendon-bone healing with direct interference screw fixation to confirm the potential of this advanced method.     

Correlation of bone tunnel diameter with quadrupled hamstring graft fixation strength using a biodegradable interference screw

Purpose: The purpose of this study was to determine whether the ultimate load at failure of a quadrupled hamstring tendon graft (QHT) fixed with a biodegradable interference screw is improved with a more precise match of the bone tunnel diameter to the diameter of the QHT. Type of Study: Biomechanical testing. Methods: In group A, 8 cadaver knees with a mean age of 69.4 years (range, 60 to 76) were used. QHT graft diameters were measured using sleeves in standard 1.0-mm increments, with matching bone tunnels drilled in 1.0-mm increments. In group B, 9 cadaver knees, with a mean age of 66.5 (53 to 81) were used. Grafts were measured using sleeves in 0.5-mm increments and matching bone tunnels in 0.5-mm increments were drilled. In both groups, the QHT grafts were fixed with a biodegradable interference screw (BioScrew, Linvatec, Largo, FL) in both the tibia and the femur. Tendon interference fixation was tested to failure using a material testing device that tensioned the grafts directly in line with the bone tunnels. Bone mineral density was measured using dual photon absorptimetry for the metaphyseal area of the tibias and femora in the area of interference screw fixation. Results: Femoral maximum load at failure significantly improved from 341 N in the 1.0-mm group to 530 N (P <.05) in the 0.5-mm group; the tibial maximum load at failure improved from 221 N to 308 N (P =.35). Conclusions: Fixation strength results of this study suggest that commercially available instrumentation could be improved with sleeves and reamers available in 0.5-mm increments.Arthroscopy: The Journal of Arthroscopic and Related Surgery, Vol 18, No 8 (October), 2002: pp 901–907     

Biomechanical comparison of hamstring and patellar tendon graft anterior cruciate ligament reconstruction techniques: The impact of fixation level and fixation method under cyclic loading

Purpose: To mechanically test different reconstruction techniques of the anterior cruciate ligament (ACL) under incremental cyclic loading and to evaluate the impact of the level and method of graft fixation on tensile properties of each technique. Type of Study: In vitro biomechanical study. Methods: Four hamstring and 1 patellar tendon reconstruction techniques were performed on 40 young to middle-aged human cadaveric knees (average age, 39 years). An anterior drawer with increasing loads of 20 N increments was applied at 30° of knee flexion. Anatomic, direct interference screw fixation was tested in 2 hamstring and in the patellar tendon groups. Nonanatomic (extracortical) graft anchorage was tested in the remaining 2 hamstring groups with indirect graft fixations on both sides and the combination of indirect tibial and direct femoral fixation. Structural properties were determined throughout the cyclic loading test. Results: The more anatomic reconstruction techniques provided significantly higher structural properties and smaller loss of fixation compared with nonanatomic, extracortical fixation, with indirect repair on both fixation sites resulting in the lowest structural properties. The tibial fixation site was the weakest link in all of the anatomic reconstructions. Patellar tendon fixation with attached bone blocks in both bone tunnels significantly improved construct stiffness and decreased graft slippage. Conclusions: The results of this study suggest that anatomic fixation should be preferred for anchorage of hamstring tendons and linkage materials should be avoided. Direct soft-tissue fixation with interference screws still allows considerable graft slippage, which can be limited by using a bone block or application of a backup or hybrid fixation, especially on the tibial fixation site.Arthroscopy: The Journal of Arthroscopic and Related Surgery, Vol 18, No 3 (March), 2002: pp 304–315     

Effects of initial graft tension on knee stability after anterior cruciate ligament reconstruction using hamstring tendons: a cadaver study

Purpose: Tension degradation within hamstring grafts and anterior knee laxity were analyzed in a cadaveric anterior cruciate ligament (ACL) reconstruction model undergoing cyclic motion. It was hypothesized that suture fixation of a hamstring graft would lose tension during cycling initially and then stabilize, and that anterior knee laxity would increase as tension was lost. Hamstring grafts fixed under 3 different loads were evaluated to determine how initial graft tension affected knee laxity after cyclic motion. Type of Study: Cadaveric biomechanical analysis. Methods: Eighteen pairs of fresh-frozen hamstring tendons were tested on 2 cadaveric knees undergoing ACL reconstruction. The hamstring pairs were separated equally and randomly into one of 3 tension groups: 68 N (15 lb), 45 N (10 lb), and 23 N (5 lb). The loads were applied to the graft at 30° of flexion, and the grafts were secured to the tibia with a suture and post technique. The knee was then cycled 1,000 times using an Instron machine (Instron, Canton, MA) through a range of motion between 0° to 90°. Constant monitoring and recording of graft tension was performed. A KT-1000 (Medmetrics, San Diego, CA) was performed (1) on the intact knee, (2) after ACL excision, (3) after ACL reconstruction and initial graft fixation, and (4) at the completion of the 1,000 cycles. An analysis of variance test was used to evaluate data. Results: The tension within the grafts after 1,000 cycles decreased to 34.5 N (7.6 lb), 16.8 N (3.7 lb), and 15.4 N (3.4 lb) from the preloads of 68, 45, and 23 N, respectively (P < .05 in all cases). This represented an average decrease of 50.2% of the initial tension after 1,000 cycles. Manual-maximum KT testing of the intact knees was 5.8 ± 0.3 mm, and after ACL excision was 13.2 ± 0.9 mm. KT testing revealed 6.0 ± 0.9 mm, 8.1 ± 1.9 mm, and 8.9 ± 1.1 mm of anterior translation after fixation in the tension groups of 68, 45, and 23 N, respectively. After 1,000 cycles, the translation increased to 7.8 ± 1.0 mm, 10.5 ± 1.9 mm, and 10.3 ± 1.5 mm, respectively. Conclusions: This study showed that initial graft tension decreases with cyclic loading, resulting in increased knee laxity. To restore anterior translation to within 3 mm of the native ACL condition after cyclic loading, approximately 68 N of initial tension is required using this fixation technique.     

Hamstring tendon fixation using interference screws: a biomechanical study in calf tibial bone

It has recently been shown that graft fixation close to the ACL insertion site is optimal in order to increase anterior knee stability. Hamstring tendon fixation using interference screws offers this possibility and a round threaded titanium interference screw has been previously developed. The use of a round threaded biodegradable interference screw may be equivalent. In addition, to increase initial fixation strength, graft harvest with a distally attached bone plug may be advantageous, but biomechanical data do not exist. This study compares the initial pullout force, stiffness of fixation, and failure modes of three strand semitendinosus grafts in 36 proximal calf tibiae using either biodegradable poly-(D,L-lactide) (Sysorb; Sulzer Orthopaedics Ltd, Munsingen, Switzerland) or round threaded titanium (RCI; Smith & Nephew DonJoy, Carlsbad, CA) interference screws, harvested either without (biodegradable: group I, titanium III) or with (biodegradable: group II, titanium: group IV) attached tibial bone plugs. Maximum pullout force in group I (507 ± 93 N) was significantly higher than in group III (419 ± 77 N). Pullout force of bone plug fixation was significantly higher than that of direct tendon fixation (717 ± 90 N in group II and 602 ± 117 N in group IV). Pullout force of biodegradable fixation was significantly higher in both settings. These results indicate that initial pullout force of hamstring-tendon graft interference screw fixation can be increased by using a biodegradable interference screw. In addition, initial pullout force of hamstring-tendon graft fixation with an interference screw can be greatly increased by harvesting the graft with its distally attached tibial bone plug.Arthroscopy 1998 Jan-Feb;14(1):29-37     

Impact of tendon suturing on the interference fixation strength of quadrupled hamstring tendon grafts

Introduction

Interference screw fixation of soft tissue grafts has been a widely used fixation technique for cruciate ligament reconstruction. Suturing of the graft construct prior to graft fixation has been proposed to increase fixation strength; however, the effect on mechanical properties has not been well characterized. The goal of this study was to determine whether uniform suturing of the tendon graft affects (1) ultimate fixation strength of the hamstring tendon graft and (2) motion of the tendon in the bone tunnel during cyclic loading when comparing sutured grafts vs. unsutured grafts.

Method

Eight pairs of matched mature porcine tibias (age <2 years) and eight paired fresh-frozen human quadrupled hamstring tendon grafts were used. One quadrupled graft from each pair was placed into one of two groups. In the group A a single cerclage suture 3 cm from the doubled end of the graft was placed to join the four tendon strands. In group B a heavy suture was used to tightly unite the four strands of tendon graft to provide a better grip for the interference screw during fixation. The grafts were placed in tibial bone tunnels that matched the graft’s diameter and fixed with an interference screw. The looped end of the graft and the attached tibia were rigidly fixed in a material testing machine. The graft constructs were subjected to 100 cycles of 20–250 N load, followed by a load-to-failure test. In addition, a motion analysis system was used during cyclic testing to better determine the amount of elongation at the graft–tunnel interface. Statistical analysis of the failure load and stiffness and the overall elongation following cyclical loading was performed using the Wilcoxon rank sum test. Level of significance was set at p < 0.05.

Results

Elongation at the tendon–bone interface during sub-maximal cyclic loading was 2.4 ± 1.4 mm (unsutured) vs. 2.0 ± 0.7 mm (sutured) (p > 0.05). Failure load of the grafts without sutures (634 ± 86 N) was significantly lower than with the sutures (837 ± 183 N). Ultimate stiffness of group A (283 ± 34 N/mm) was lower than that of group B (331 ± 51 N/mm); however, this was not statistically significant (p = 0.051).

Conclusion

This study confirms that suturing of the graft construct before interference screw fixation may increase ultimate failure load. However, an improvement of structural properties in response to cyclic loading with sub-maximal loads could not be confirmed. Clinicians using interference screw fixation may suture the graft to improve fixation strength; however, suturing does not appear to allow a more aggressive rehabilitation after surgery.     

Biomechanical testing of hamstring graft tibial tunnel fixation with bioabsorbable interference screws

Purpose:This study evaluated the failure mode, maximum load at failure, displacement at failure, and stiffness differences of quadrupled hamstring graft-tibial tunnel fixation using 28-mm, tapered 35-mm, or bicortical 17- and 20-mm bioabsorbable interference screws (Arthrex, Naples, FL).Type of Study:Biomechanical study.Methods:Nine matched pairs (18 specimens) of young cadaver tibias (mean bone mineral density [BMD] = 0.847 g/cm², range, 0.689 to 1.11 g/cm²) were divided into 3 groups of 6 specimens. Kruskal Wallis analysis of variance and Mann-Whitney U tests post hoc comparisons were used to assess group differences (P < .05).Results:Maximum load at failure for the 28-mm screw was 488.2 ± 197 N, with a displacement of 18.4 ± 7.5 mm and a stiffness modulus of 38.9 ± 7.0 N/mm. Maximum load at failure for the tapered 35-mm screw was 844.8 ± 121.4 N, with a displacement of 15.3 ± 1.6 mm and a stiffness modulus of 70.5 ± 21.1 N/mm. Maximum load at failure for bicortical screw fixation was 543.7 ± 266.5 N, with a displacement of 17.7 ± 6.6 mm and a stiffness modulus of 57.7 ± 14.9 N/mm. Fixation using the tapered 35-mm screw displayed greater maximum load at failure than either 28-mm screw fixation (P = .015) or bicortical screw fixation (P = .037). Significant differences were not evident for displacement. Both tapered 35-mm (P = .016) and bicortical screw (P = .026) fixation displayed greater stiffness than 28-mm screw fixation. All constructs failed by pullout.Conclusions:Fixation using a single tapered 35-mm screw displayed increased maximum load at failure compared with the 28-mm screw or bicortical fixation. Both the tapered 35-mm screw and bicortical fixation showed greater stiffness than fixation using a 28-mm screw. Use of a single 35-mm screw for quadrupled hamstring graft-tibial tunnel fixation may be preferred for patients with poor tibial BMD.     

A bioabsorbable plug in bone-tendon-bone reconstruction of the anterior cruciate ligament: Introduction of a novel fixation technique

Purpose: Our aim was to compare the fixation strength of a novel plugging technique with that of the conventional interference technique in bone–patellar tendon–bone reconstruction of the anterior cruciate ligament. Type of Study: Randomized experimental study. Methods: Twenty matched pairs of porcine knees were randomly assigned to 2 groups. The bone block of the graft was secured in the femoral drill hole with either the new bioabsorbable poly-L-lactide/D-lactide (PLA 96/4) copolymer plug (plugging technique) (n = 20) or a conventional interference screw (interference technique) (n = 20). Ten pairs were subjected to a single cycle loading test at a rate of 50 mm/min while the remaining 10 pairs underwent a cyclic loading test to further assess the quality of the fixation. The cyclic loading test consisted of 1,500 loading cycles between 50 and 200 N at half-hertz frequency, after which the specimens were loaded to failure at a rate of 50 mm/min. Results: In the single cycle loading test, the average ultimate failure load was 1,061 ± 342 N in the plugging technique group and 971 ± 260 N in the interference technique group (P =.57). Significant group differences were found neither in the yield loads nor in the stiffness of the fixations. In the cyclic loading, significant displacement difference was not observed between the 2 fixation techniques. There were neither significant group differences with regard to the ultimate failure load (plugging technique 994 ± 376 N versus interference technique 1,001 ± 343 N, P =.97) nor yield load of the fixations in the subsequent single cycle loading. Conclusions: The results of this study indicate that, in anterior cruciate ligament reconstruction, the new plugging technique is a reasonable alternative for fixation of the femoral site of a bone–patellar tendon–bone graft.Arthroscopy: The Journal of Arthroscopic and Related Surgery, Vol 17, No 2 (February), 2001: pp 144–150     

Biomechanical comparison of different fixation methods on the tibial side in anterior cruciate ligament reconstruction: a biomechanical study in porcine tibial bone

Background The fixation strength of the hamstring tendon graft on the tibial side is considered the weak point in anterior cruciate ligament (ACL) reconstruction. The purpose of this study was to compare the biomechanical characteristics of four types of ACL reconstruction methods on the tibial side. Methods Extensor digitorum tendons harvested from fresh bovine forelimbs were used as the graft materials in this study. Twenty-eight porcine tibias were divided into four groups based on different fixation methods. Group D was fixed using a double spike plate (DSP), group I was fixed using an interference screw, group DI-80 was fixed using both an interference screw and DSP (80 N tension was applied to DSP), and group DI-150 was fixed using both an interference screw and DSP (150 N tension was applied to DSP). Results The displacement of the grafts in response to 500 cycles of 0–150 N loading was significantly greater in groups D (10.3 ± 15 mm) and I (5.5 ± 1.7 mm) than that in groups DI-80 (2.1 ± 0.3 mm) and DI-150 (1.2 ± 0.4 mm), with no significant differences between groups DI-80 and DI-150. The ultimate failure load and stiffness were significantly higher in groups DI-80 (745 ± 156 N, 103 ± 17 N/mm) and DI-150 (801 ± 129 N, 151 ± 35 N/mm) than those in groups D (374 ± 53 N, 70 ± 13 N/mm), and I (520 ± 76 N, 78 ± 18 N/mm). The stiffness of group DI-150 was significantly greater than that of group DI-80. Conclusions Our results indicate that the initial fixation strength of the hamstring tendon can be increased by using an interference screw combined with DSP on the tibial side.     

The effect of interference screw diameter on soft tissue graft fixation

Tibial fixation of soft-tissue grafts is a weak link in anterior cruciate ligament reconstruction. Previous studies have examined varying interference screw lengths, screw types and tunnel sizes as means to improve graft fixation. We hypothesized that increasing interference screw diameter would significantly increase the maximum load to failure of the graft and decrease the graft's initial slippage. Seventy tibialis anterior and tibialis posterior tendons were divided, looped, trimmed, and sutured to simulate 4-strand hamstring grafts. These grafts were then inserted into composite bone blocks having pre-drilled 8 mm holes and fixed with 8 mm, 9 mm, 10 mm, 11 mm, or 12 mm interference screws. Fourteen grafts were tested for each screw size. The graft was first cyclically loaded from 50 N to 250 N at 0.3 Hz for 100 cycles to measure graft slippage. The graft was then tested to failure at 0.5 mm/sec to determine the maximum load to failure and mode of failure. Graft slippage was not affected by screw diameter. Maximum load to failure increased with increasing screw diameter up to 11 mm; 11 mm screw fixation was 20% stronger than 8 mm screw fixation. In this model, no increase in graft fixation was seen in by increasing interference screw diameter beyond 3 mm of the tunnel diameter.     

Primary stability of bone-patellar tendon-bone graft fixation with biodegradable pins

Purpose: We evaluated the initial bone-patellar tendon-bone (BPTB) graft fixation strength of biodegradable pins compared with interference screws in anterior cruciate ligament reconstruction using bovine knees. Type of Study: Biomechanical in vitro study. Methods: Ten BPTB grafts from human donors fixed with 2 biodegradable 2.7-mm pins (Rigid Fix; Ethicon, Mitek Division, Norderstedt, Germany) crossing the bone block perpendicular and 10 BPTB grafts fixed with conventional biodegradable interference screws (Absolute Absorbable Interference Screw; Innovasive Devices, Marlborough, MA) underwent ultimate single-cycle failure loading at a rate of 200 mm/min. The grafts were fixed to bovine tibia to simulate young human femoral bone density. Failure mode, displacement before failure, and ultimate failure load were tested with a testing machine. The pullout force was in line with the bone tunnel to simulate a worst case scenario. Results: The failure mode for cross pins was either fracture of the bone block (5 specimens) or fracture of the articular pin (5 specimens). The failure mode for interference screws was slippage past the screw in all specimens. In the single cycle loading test, the mean yield load for the biodegradable pins was 400.2 (± 122.4) N, maximum load, 524.6 (± 136.6) N, with a mean stiffness of 155.2 (± 32.4) N/mm. The yield load at failure for the interference screw was 402.7 (± 143.9) N, maximum load 515.7 (± 168.5) N with a mean stiffness of 168 (± 42) N/mm. Conclusions: Fixation of a BPTB graft with 2 biodegradable 2.7-mm pins (Rigid Fix) leads to primary stability that is comparable to fixation with biodegradable interference screws.     

Interference screw position and hamstring graft location for anterior cruciate ligament reconstruction

Anterior cruciate ligament reconstruction with hamstring tendon graft and interference screw fixation has recently been considered. Concerns for the use of interference screws with soft tissue grafts include damage to the graft during screw insertion, decreased fixation strength, and a decrease in the bone-tendon contact area for healing within the tunnel when the screw is placed in an eccentric position. This last concern could be addressed by placing the interference screw centrally between the four limbs of the hamstring graft. The purpose of this study was to determine the mode of failure, the pullout force, and graft slippage before graft fixation failure of hamstring tendons fixed with an interference screw positioned eccentrically in relation to the hamstring tendons verses an interference screw positioned centrally between the four graft limbs. The semitendinosus and gracilis tendons were harvested from six, fresh cadaveric specimens. Each tendon was divided into two segments of equal length. Both the semitendinosus and gracilis tendon segments were looped to form four strands. The specimens were then fixed with a bioabsorbable interference screw in the two different positions and pulled from a standardized polyurethane foam. All tendons in both groups failed by pulling out from between the interference screw and tunnel, regardless of the screw position. No tendon was cut by the screw in either group. There was no significant difference between the forces required to produce specific amounts of graft slippage between the two fixation techniques tested. There was no significant difference between the average total slippage at maximum pullout, 11.8 mm for the screw placed in the eccentric position and 13.7 mm for the screw placed in the central position. The maximum pullout force averaged 265.3 N for the screw placed in the eccentric position, and 244.7 N for the screw placed in the central position; these values were not significantly different. Placement of the interference screw in the central position did not compromise strength and it improves graft contact within the bone tunnel. Interference screw fixation, when applied against a bone plug, has been shown to consistently have a pullout force of more than 400 N.Arthroscopy 1998 Jul-Aug;14(5):459-64     

Interference screw divergence in femoral tunnel fixation during endoscopic anterior cruciate ligament reconstruction using hamstring grafts

Purpose:To compare the divergence angles between bioabsorbable interference screws inserted into the femoral tunnel with the screwdriver placed through the anteromedial portal to those inserted with the screwdriver placed through the tibial tunnel and to examine the effect of the femoral tunnel interference screws’ divergence angles on fixation strength of hamstring grafts after anterior cruciate ligament (ACL) reconstruction using hamstring grafts. Type of Study:Cadaveric biomechanical pullout study. Methods:ACL reconstruction was performed in 8 pairs of fresh-frozen human cadaveric knees using hamstring grafts fixed within the femoral tunnels using bioabsorbable interference screws. Within matched pairs, 1 screw was placed into the femoral tunnel using a screwdriver placed through the tibial tunnel (group 1), and in the other knee it was placed into the femoral tunnel using a screwdriver placed through the anteromedial portal (group 2). Radiographs were taken to measure the degree of divergence between the interference screw and the femoral tunnel. After disarticulation, pullout strength was then measured using a cyclic-loading model. Results:In group 2, there was significantly more divergence between the screw and the femoral tunnel compared with group 1, particularly in the sagittal plane (average 14.4° compared with 3.4°, P =.00014). With the number of specimens available for comparison, no significant difference was detected between the 2 groups with regard to 3 mm and 5 mm of pullout when cyclically loaded (P =.77 and.74, respectively). Conclusions: The increased technical difficulty, combined with the potential risks of tibial tunnel widening and graft damage, with placement of the screwdriver through the tibial tunnel for the purpose of decreasing femoral interference screw divergence in ACL reconstruction using hamstring grafts may not be justified.Arthroscopy: The Journal of Arthroscopic and Related Surgery, Vol 18, No 5 (May-June), 2002: pp 510–514     

Tibiale Press-fit-Fixierungen von Beugesehnen zur Rekonstruktion des vorderen Kreuzbandes

Background

Press-fit fixation of hamstring tendon autografts for anterior cruciate ligament reconstruction is an interesting technique because no hardware is necessary. This study compares the biomechanical properties of press-fit fixations to an interference screw fixation.

Methods

Twenty-eight human cadaveric knees were used for hamstring tendon explantation. An additional bone block was harvested from the tibia. We used 28 porcine femora for graft fixation. Constructs were cyclically stretched and then loaded until failure. Maximum load to failure, stiffness and elongation during failure testing and cyclic loading were investigated.

Results

The maximum load to failure was 970±83?N for the press-fit tape fixation (T), 572±151?N for the bone bridge fixation (TS), 544±109?N for the interference screw fixation (I), 402±77?N for the press-fit suture fixation (S) and 290±74?N for the bone block fixation technique (F). The T fixation had a significantly better maximum load to failure compared to all other techniques (p<0.001).

Conclusion

This study demonstrates that a tibial press-fit technique which uses an additional bone block has better maximum load to failure results compared to a simple interference screw fixation.     

Biomechanical comparison of quadriceps tendon fixation with patellar tendon bone plug interference fixation in cruciate ligament reconstruction

Purpose: The purpose of this study was to use current fixation techniques and compare the stiffness and ultimate tensile failure of the tendinous end of the quadriceps tendon (QT) with the bone plug end of the bone–patellar tendon–bone (BPTB) graft using current techniques of fixation. Type of Study: Randomized trial of elderly cadaver knees. Materials and Methods: Tibial and femoral biodegradable interference fixation and femoral EndoButton (Smith & Nephew, Acufex, Mansfield, MA) fixation in bone tunnels with the QT and the BPTB graft were compared by using 10 pairs of elderly cadavers and biomechanical testing. Two groups, fixation at time zero (simulating fixation in the operating room) and testing after 1,000 loading cycles (simulating patient rehabilitation exercises), were used. Results: At time zero fixation, stiffness of the soft tissue QT tibial tunnel interference fixation was 59% less stiff than the stiffness of the interference fixation of a BPTB plug in a femoral tunnel (P = .11). The EndoButton femoral fixation resulted in a decrease in stiffness at time zero compared with femoral tunnel interference fixation of the soft tissue QT (P = .03). All groups improved stiffness with cycling the construct to 1,000 cycles. Conclusions: Placement of the QT tendinous end of the graft in the femoral bone tunnel when using a interference fixation will approximate the stiffness of a bone plug in the tibial bone tunnel with interference fixation. The EndoButton fixation is not as stiff as either of the femoral interference fixation options. The addition of more than 20 loading cycles could remove laxity from the graft fixation–graft cruciate ligament complex and improve its stiffness.     

肌腱结嵌压固定法重建前交叉韧带生物力学实验研究

目的探讨绳肌腱结嵌压固定法重建前交叉韧带(ACL)影响初始固定效果的相关因素及对策。方法采用猪膝关节模拟重建ACL不同术式,即绳肌腱结股骨隧道嵌压固定和胫骨端肌腱编织缝合骨桥打结固定法,与骨-髌腱-骨两端界面螺钉固定法,比较其生物力学初始固定最大拔出载荷、抗拉刚度和位移等生物力学指标。结果最大抗拉载荷肌腱结组与正常ACL组接近,无显著性差异;肌腱结组大于骨-髌腱-骨界面螺钉固定组。抗拉载荷在100N和400N时的位移两组无显著性差异。胫骨端肌腱编织缝合骨桥上打结固定组最大抗拉载荷大于BPTB界面螺钉固定组和肌腱编织缝合后界面螺钉固定组。抗拉刚度正常ACL组>骨-髌腱-骨组>绳肌腱结组。最大位移正常ACL<髌腱骨组<肌腱结组。结论绳肌腱结嵌压固定法抗拉强度和刚度完全可以满足重建后ACL的生理需求;术中克服位移因素,是有效防止ACL重建术后松弛的关键。     

腘绳肌腱结嵌压固定法重建交叉韧带的临床应用与生物力学研究

目的探讨腘绳肌腱结嵌压固定法重建交叉韧带的可行性。方法对52例陈旧性前、后交叉韧带损伤患者在关节镜下行双股腘绳肌腱中间打结,嵌入瓶颈状股骨隧道内固定,胫骨端采用肌腱编织缝合在骨桥上打结固定,重建交叉韧带。其中前交叉韧带25例,前、后十字韧带同时重建15例,后交叉韧带12例。生物力学实验采用猪膝关节。股骨端固定分为肌腱结嵌入组(n=13)和骨髌腱骨(B PT B)介面螺钉固定组(B PT B介面钉组,n=11)。胫骨端固定分为肌腱编织缝合线在骨桥打结组(n=7)、肌腱编织缝合介面螺钉组(n=8)。进行最大拔出强度、最大位移和固定刚度等力学实验。结果术后随访49例,平均14 6个月,Lanchman试验阴性46例,阳性3例。术后Lysholm评分由术前56 7分提高到92 8分。按膝关节疗效评定标准,优46例,良3例。生物力学实验最大拔出强度肌腱结嵌入组高于B PT B介面钉组;固定刚度肌腱结嵌入组小于B PT B介面钉组;最大位移肌腱结嵌入组大于B PT B介面钉组。胫骨端固定抗拉强度和刚度骨桥打结组优于介面螺钉组。结论腘绳肌腱结嵌压固定重建交叉韧带生物力学抗拉强度能满足生理需求,方法可行;可克服位移因素,降低韧带松弛率,提高疗效。     

Initial fixation strength of modified patellar tendon grafts for anatomic fixation in anterior cruciate ligament reconstruction.

Recently it has been shown that anatomic tibial graft fixation in anterior cruciate ligament (ACL) reconstruction is preferable in order to increase isometry and knee stability. To facilitate anatomic patellar tendon graft fixation, customized graft length shortening is necessary. The purpose of this study was to compare the initial fixation strength of four different shortened patellar tendon grafts including three bone plug flip techniques and direct patellar tendon-to-bone interference fit fixation in a model with standardized bone density. Ninety calf tibial plateaus (22 to 24 weeks old) with adjacent patella and extensor ligaments were used. Tendon grafts were shortened by flipping the bone plug over the tendon leaving a tendon-tendon-bone (TTB) construct and, as the first modification in the opposite direction resulting in a tendon-bone-tendon (TBT) construct. The second modification consisted of the TBT construct with interference screw position at the lateral aspect of the bone plug (TBTlat). As the fourth modification the tendon graft was directly fixed (Tdirect) with an interference screw. In addition, a round-threaded titanium (RCI; Smith & Nephew DonJoy, Carlsbad, CA), a round-threaded biodegradable screw (Sysorb; Sulzer Orthopedics, Münsingen, Switzerland), and a conventional titanium interference screw (Arthrex Inc, Naples, FL) were compared. We found that TTB (mean 441 N for biodegradable screw, 357 N for RCI screw, 384 N for conventional screw) and TBT (mean 407 N for biodegradable screw, 204 N for RCI screw, 392 N for conventional screw) construct fixation achieves comparable fixation strength, although failure in the TTB was due to tendon strip off at its ligamentous insertion. The highest failure load was found in TBTlat fixation (mean 610 N for biodegradable screw, 479 N for RCI screw). Therefore, this technique should be recommended when using a tendon flip technique. The failure load for Tdirect fixation (mean 437 N for biodegradable screw, 364 N for RCI screw) was similar to that of TTB and TBT fixation, which may indicate that a patellar-tendon graft harvested without its patellar bone plug and directly fixed with an interference screw is equivalent to a flipped graft. This may additionally reduce harvest site morbidity and eliminates the risk of patellar fracture. The fixation strength of round-threaded biodegradable and conventional titanium interference screws was similar, whereas that of round-threaded titanium screws was significantly lower in the patellar tendon flip-techniques. However, it should be taken into consideration that round-threaded titanium screws are proposed for direct tendon-to-bone fixation.     

Quadrupled semitendinosus-gracilis autograft fixation in the femoral tunnel: a comparison between a metal and a bioabsorbable interference screw

Although semitendinosus-gracilis (SG) grafts for anterior cruciate ligament reconstruction have many potential benefits, effective fixation remains a challenge. This study assessed differences between the maximum pullout forces needed to detach a quadrupled SG graft from a femoral tunnel when secured by either a metal or a bioabsorbable interference screw. Sixteen paired fresh frozen quadrupled SG autografts (x, 8.4 mm; range, 7-10 mm) from 8 donors were anchored into cadaveric femoral tunnels by either a 7-mm metal or a 7-mm bioabsorbable screw after bone mineral density (BMD) assessment and before undergoing a longitudinal 20 mm/min traction force. Statistical analysis compared BMD (gm/cm2), insertional torque (N-m), and maximum load at pullout (N) between screw types. Insertional torques (.28-1.21, N-m range) did not correlate (P>.05) to BMD or maximum load at pullout (x ± S.D.) 242 ± 90.7 N (metal screw) and 341.1 ± 162.9 N (bioabsorbable screw). Differences did not exist between the maximum load at pullout for bioabsorbable or metal screw fixation (P = .16). Careful graft preparation, sizing, and matched tunnel placement enables interference fit and fixation capable of reliably withstanding the low- level rehabilitation loads to which the graft is exposed until bony ingrowth occurs.Arthroscopy 1998 Apr;14(3):241-5