右侧肢体活动不利

<正>病历摘要患者男性,51岁。因阵发性右侧肢体活动不利10d、持续不缓解1d,于2013年10月5日入院。患者入院前10d无明显诱因出现右侧肢体活动不利,右上肢不能抬起、持物,右下肢站立、行走不能,无头痛、头晕,无恶心、呕吐,无视物     

右侧肢体活动不利

病历摘要 患者男性,51岁。因阵发性右侧肢体活动不利10d、持续不缓解1d,于2013年10月5日入院。患者入院前10d无明显诱因出现右侧肢体活动不利,右上肢不能抬起、持物,右下肢站立、行走不能,无头痛、头晕,无恶心、呕吐,无视物模糊或成双,无耳聋、耳鸣,无意识障碍或言语障碍,     

桶人综合征一例

临床资料 患者女,80岁,因"双上肢无力20余天"于2011年3月25日入我院.入院20余天前,患者半夜醒来时感到左侧肩部疼痛,左上肢不能抬起,随后又出现右侧肩部疼痛,右上肢不能抬起,不伴有肢体麻木、双下肢无力、大小便障碍,急诊入当地医院,治疗20余天后,患者右上肢力量较前有所好转,肩部疼痛缓解,左上肢力量无明显缓解,仍伴有肩部疼痛,遂转入我院.     

三叉神经痛微血管减压术后疼痛不缓解的治疗体会

目的 探讨三叉神经微血管减压(MVD)术后患者疼痛不缓解的治疗方法 . 方法 对北京大学人民医院神经外科自2005年1月至2009年6月收治的50例原发性三叉神经痛患者行MVD术后手术效果进行回顾性分析.对术后疼痛不缓解的患者应用经皮卵圆孔三叉神经池甘油封闭术治疗. 结果 50例患者MVD术后有3例疼痛不缓解.3例患者中对责任血管实施减压者2例,无责任血管仅行梳理者1例;3例患者均有蛛网膜粘连增厚.应用经皮卵圆孔三叉神经池甘油封闭术治疗后疼痛消失. 结论 尽管实施有效的MVD术仍不能保证所有患者术后疼痛缓解,特别是无责任血管者,术后持续疼痛可能性更大.荧屏监视下经皮卵圆孔穿刺半月节甘油封闭术为MVD术后疼痛不缓解者提供了一种避免再次开颅、简便易行、安全有效的方法 .     

马凡综合征合并低颅压性头痛一例报告

患者女性，２１岁，篮球运动员。因头痛２年，加重４天于１９９７年１０月７日入院。患者始于１９９５年反复出现运动后前额部胀痛，立位时明显，平卧位减轻，极易疲劳，无恶心、呕吐、心悸。曾有３次一过性晕厥。未治疗。入院前４天无明显诱因症状加重，平卧位亦不能缓解...     

反复意识障碍伴抽搐发作4年余

正病历摘要患者女性,21岁,因反复意识障碍伴抽搐发作4年余,于2017年12月29日入院。患者4年余前(2013年7月)无明显诱因出现反复发作性意识障碍伴抽搐发作,有时表现为右侧肢体僵直、阵挛,头部和眼球右偏,口吐白沫,面色发白,无大小便失禁、舌咬伤,否认发作前先兆,持续约5 min后自行缓解,遗留意识模糊,能听懂他人言语但不能说话,约30 min后恢复正常,不能回忆发作过程,发作频率1次/月,就诊于当     

平山病一例

<正>患者男性,28岁,因渐进性右上肢远端无力伴肌萎缩5年,于2016年2月19日至我院门诊就诊。患者5年前无明显诱因出现右手手指无力,寒冷时加重,逐渐出现右手手指活动笨拙、不能并拢,穿针引线等精细活动明显受限,症状持续无明显缓解,伴右手肌萎缩,无明显肉跳感,其他肢体活动正常,无疼痛、麻木等感觉异常,无言语障碍、吞咽困难等。患者自发病以来,精神、睡眠、饮食尚可,大小便无明显异常,体重无明显改变。既往史、个人     

类癫痫样发作的胰腺肿瘤一例

患者男,65岁,农民.3个月前无任何诱因出现发作性意识障碍伴阵发性肌强直、面色苍白、大汗,半小时后缓解,事后对发作时的情况不能回忆.近1个月类似发作2次.入院前1 d清晨再次发作,四肢强直抽搐、小便解在身上,发作缓解时神志恍惚、乱语,说"同鬼打架""喊妻子拿刀来"等.到当地卫生院输液治疗,病情无缓解,于2006年9月17日16时入本科.既往无重大疾病.性格开朗、人际关系较好.     

椎管内结核瘤1例报告

女性,22岁,因腰腹部疼痛8个月,不能行走10d入院。患者8月前因不明原因出现腰部隐痛,继而发生右下腹部疼痛,无恶心呕吐,腹胀腹泻,在当地医院行“阑尾切除术”后腹痛缓解,但腰痛逐渐加重,服中、西药无明显好转。入院10d前出现双下肢不能行走,以右脚为甚;早上较重,稍活动后缓解;无麻木抽搐,无结核病史。检查:腹股沟以下浅感觉减退,双下肢肌力下降,腱反射亢进,双侧病理征阳性。全身检查无     

第二届中国睡眠医学论坛通知

患者男，65岁，农民。3个月前无任何诱因出现发作性意识障碍伴阵发性肌强直、面色苍白、大汗，半小时后缓解，事后对发作时的情况不能回忆。近1个月类似发作2次。入院前1d清晨再次发作，四肢强直抽搐、小便解在身上，发作缓解时神志恍惚、乱语，说“同鬼打架”“喊妻子拿刀来”等。到当地卫生院输液治疗，病情无缓解，于2006年9月17日16时入本科。既往无重大疾病。性格开朗、     

Denervation study of synapses of organ of corti of old world monkeys

Fine structural characteristics of synapses in the spiral organ of Corti were examined, with reference to differences between inner and outer haircell systems, and to location of neurons of origin of efferent axons. Surgical interruption of crossed olivocochlear bundle, of vestibular nerve, of facial nerve, and excision of superior cervical ganglia were used to determine the pathways of efferent axons. Interruption of the vestibular nerve near the brainstem results in degeneration of all efferent terminals on outer hair cells. Mid-line lesions at, and caudal to, the facial colliculus result in degeneration of about half of these efferent terminals. Efferent synaptic bulbs to the inner hair-cell system are small, of the order of one micron, and form type 2 junctions with afferent dendrites. They tend to have more large dense-core vesicles (about 80 nm) than the large efferent terminals of the outer hair-cell system, and appear to be the terminals of axons in the habenula perforata, which exhibit varicosities laden with large dense core vesicles. The varicosities are unaffected by excision of the superior cervical ganglia. So far as our material can reveal, it appears that the varicosities in the habenula perforata do not survive vestibular root interruption, nor do the efferent processes in the internal spiral bundle or at the base of inner hair cells. Most interestingly, the afferent processes of the inner hair-cell system, as identified for example by their relation to pre-synaptic bodies in the inner hair cells, are subject to a trans-synaptic reaction after severance of the vestibular root. They undergo a dramatic cytological transformation, characterized by increase of volume, engorgement with microtubules, microfilaments, microvesicles of various sizes, and clusters of lysosomes. Thus, both the efferent and afferent terminals of the inner hair-cell system show marked cytological differences from the corresponding terminals of the outer hair cell system.     

Summary of legislation of 1935 of interest to the department of Mental Hygiene

Psychiatric Quarterly -     

Summary of legislation of 1941 of interest to the Department of Mental Hygiene

Psychiatric Quarterly -     

Asymmetry of on- and off-pathways of blue-sensitive cones of the retina of macaques

Macaque retinal ganglion cells whose receptive-field center recieves input from blue-sensitive cones show an overt asymmetry of the frequency of ON-center and OFF-center varieties, an asymmetry not present in ganglion cells whose center receives input from the other two cone types. A similar asymmetry of ON/OFF responses is found in the local electrotetinogram (d-wave) mediated by signals from blue-sensitive cones. ‘Blue-ON-center’ ganglion cells have larger receptive-field centers and shorter conduction latencies than other opponent-color varieties, suggesting an appreciable degree of receptor convergence and presumably large cell bodies. Intracellular stainings of these neurons with Procion Yellow show that they correspond to diffuse stratified (Parasol) ganglion cells whose flat-topped dendritic arborization stratifies in the sclerad half of the inner plexiform layer. In view of the known characteristics of macaque bipolar cells and of the ON/OFF asymmetry, it is proposed that these ganglion cells are postsynaptic to cone-specific flat bipolars possibly mediating sign-inverting synaptic contacts. The results also indicate a reversal, for the blue-cone pathway, of the ON/OFF lamination of the inner plexiform layer that has recently been described in other species.     

Mechanism of action of tubocurarine on nicotinic cholinoreceptors of neurons of the sympathetic ganglia of rats

Tubocurarine (Tc) effect on membrane currents elicited by acetylcholine (ACh) was studied in isolated superior cervical ganglion neurons of rat using patch-clamp method in the whole-cell recording mode. The "use-dependent" block of ACh current by Tc was revealed in the experiments with ACh applications, indicating that Tc blocked the channels opened by ACh. Mean lifetime of Tc-open channel complex, tau, was found to be 9.8 +/- 0.5 s (n = 7) at -50 mV and 20-24 degrees C. tau exponentially increased with membrane hyperpolarization (e-fold change in tau corresponded to the membrane potential shift by 61 mV). Inhibition of the ACh-induced current by Tc (3-30 microM/1) was completely abolished by membrane depolarization to the level of 80-100 mV. Inhibition of ACh-induced current was augmented at increased ACh doses. It is concluded that the open channel block produced by Tc is likely to be the only mechanism for Tc action on nicotinic acetylcholine receptors in superior cervical ganglion neurons of rat.