Total pelvic clearance for advanced pelvic malignancy

Objective:  Advanced pelvic tumours require multidisciplinary care to improve outcome. This is an audit of one specialist unit's experience.
Method:  Consecutive patients referred from 2001 to 2005 for consideration of pelvic clearance were evaluated by retrospective review.
Results:  Of 100 patients assessed, 55 were considered unsuitable for surgery. Exclusions included unresectable pelvic side-wall disease (25), widespread disease (23) and severe co-morbidity (7). Forty-five patients were operated on; 22 had locally advanced disease, 14 had recurrence and nine had residual disease following previous surgery. The primary cancers were colorectal in 24, gynaecological in 10 and urogenital in 10; one patient had non-neoplastic disease. Preoperatively 39 (87%) had examination under anaesthetic (87%) and all had MR and CT imaging. Neoadjuvant radiotherapy and chemotherapy was given in 27 and 18 patients respectively. Following resection by a multi-speciality team, surgery was considered curative in 40 (90%) of cases as judged by a histologically negative margin. All patients received level 2 care postoperatively with only two requiring level 3 care. There was no 30-day mortality but there were 17 complications treated conservatively and five that required surgery.
Conclusion:  Advanced pelvic tumours require careful multidisciplinary assessment and treatment. This study shows that this can be performed safely with high levels of histological clearance of tumour.     

Relative pelvic version: an individualized pelvic incidence-based proportional parameter that quantifies pelvic version more precisely than pelvic tilt

Background Context

Pelvic tilt (PT) is used as an indicator of pelvic version with increased values indicating retroversion and disability. The concept of using PT solely as an absolute numerical value can be misleading, especially for the patients with pelvic incidence (PI) values near the upper and lower normal limits. Relative pelvic version (RPV) is a PI-based individualized measure of the pelvic version. Relative pelvic version indicates the individualized spatial orientation of the pelvis relative to the ideal sacral slope as defined by the magnitude of PI.

早期腹膜外骨盆填塞联合外固定支架治疗血流动力不稳定骨盆骨折

目的 探讨早期运用腹膜外骨盆填塞术联合骨盆外固定支架治疗血流动力不稳定骨盆骨折的临床疗效.方法 2004年12月至2009年12月,运用早期腹膜外骨盆填塞术联合骨盆外固定支架固定治疗15例血流动力不稳定骨盆骨折患者,男6例,女9例;年龄38～56岁,平均（44.0±1.2）岁.骨折根据Tile分型：B1型3例,B2-2型2例;C1-1型1例,C1-2型2例,C1-3型2例,C2型3例,C3型2例.15例患者均伴有低血容量性休克,且均采取急诊骨盆外固定支架固定与腹膜外骨盆填塞术.结果 15例患者术后的红细胞输注单位数与术前相比显著减少,血红蛋白、红细胞压积及收缩压与术前相比显著升高,差异均有统计学意义（P〈0.05）;脉率与术前相比差异无统计学意义（P〉0.05）.手术时间为30～40 min,平均（32.0±2.6）min.5例患者术后死亡,死亡时间为术后1～7 d,平均（72.0±4.2）h.在收缩压、脉率、血红蛋白、损伤严重程度评分、红细胞压积、红细胞输注单位数等方面,死亡患者与存活患者相比差异均无统计学意义（P〉0.05）.但在年龄和受伤至手术时间方面差异有统计学意义（P〈0.05）.结论 对于血流动力不稳定骨盆骨折患者,尤其是伴有低血容量性休克者,急诊行腹膜外骨盆填塞术联合骨盆外固定支架固定可以有效控制骨折端与骶前静脉丛的广泛渗血,明显改善患者的血流动力学参数,并可显著降低患者的死亡率.     

Emergent pelvic fixation in patients with exsanguinating pelvic fractures

BACKGROUND: An alternative to embolization or external pelvic fixation (EPF) in patients with multiple pelvic fractures and hemorrhage is a pelvic orthotic device (POD), which may easily be placed in the resuscitation area. Little published information is available about its effectiveness. This study evaluated the efficacy of the POD compared with EPF in patients with life-threatening pelvic fractures. STUDY DESIGN: We evaluated patients with blunt pelvic fractures over a 10-year period. Inclusion required multiple pelvic fractures with vascular disruption and severe retroperitoneal hematoma, open book fracture with symphysis diastasis, or sacroiliac disruption with vertical shear. Patients with EPF were compared with those in whom a POD was used. Outcomes included transfusions, hospital stay, and mortality. RESULTS: There were 3,359 patients with pelvic fractures who were admitted: 186 (6%) met entry criteria; 93 had EPF and 93 had POD. There were no differences in age or shock severity. Both 24-hour (4.9 versus 17.1 U, p < 0.0001) and 48-hour transfusions (6.0 versus 18.6 U, p < 0.0001) were reduced with POD. Twenty-three percent of each group underwent pelvic angiography, and 24-hour transfusion amounts for those patients were also reduced with POD (9.9 versus 21.5 U, p < 0.007). Hospital length of stay (16.5 versus 24.4 days, p < 0.03) was less with POD. Although there was decreased mortality with POD (26%) versus EPF (37%), it was not statistically significant (p=0.11). CONCLUSIONS: The therapeutic shift to POD has substantially reduced transfusion requirements and length of hospital stay, and has reduced mortality in patients with unstable pelvic fractures. POD has made a major contribution to the care of critically injured patients with the most severe pelvic fractures.     

Control of severe pelvic fracture hemorrhage with pelvic packing

The mortality of pelvic fracture caused by high ma is very high. If the fracture with massive blood loss, the mortality will reach 50%-60%.^1,2 The bleeding site usually origins from retroperitoneum. Unstable pelvic fracture can easily cause continuous retroperitoneal bleeding which is bound to a hemorrhagic shock state.     

Coccygectomy for drainage of pelvic abscesses after pelvic wounds

Ten patients who had extensive soft tissue, bony, and visceral injuries from high velocity missile wounds of the pelvis were seen with pelvic infections. Adequate drainage of the pelvis is difficult to obtain. Coccygectomy with presacral drainage of the pelvis has been found to give excellent wide open, dependent pelvic drainage in these patients.     

骨盆环重建内固定治疗不稳定骨盆骨折

[目的]探讨切开复位骨盆环重建内固定治疗不稳定性骨盆骨折的效果。[方法]17例骨盆骨折按Tile分类确定为不稳定性，对前、后环严重损伤者行前路、后路或联合入路复位固定重建骨盆环，合并脏器损伤Ⅰ期修补处理。[结果]随访13例，平均随访15个月。骨折愈合骨盆环无畸形，下地行走，无腰腿痛及步态异常。[结论]不稳定性骨盆骨折手术内固定，重建骨盆环方法恢复解剖关系，合并内脏损伤，Ⅰ期处理，疗效满意。     

Hyperthermic pelvic isolation-perfusion in the treatment of refractory pelvic cancer

Hyperthermic isolation-perfusion (I-P) was used to treat 27 patients with refractory pelvic cancer. All patients except one achieved pelvic isolation as manifested by selective pelvic heating and by pharmacologic monitoring. Patient response was good, with rapid pain relief in 75% and tumor control as detected by physical examination, computed tomographic scan, and decline in carcinoembryonic antigen levels. Pelvic drug exposure averaged 7.8 times that of systemic drug exposure. Of the 20 patients with recurrent rectal adenocarcinoma, one complete response (duration, eight months), seven partial responses (average duration, greater than or equal to 10 months), four patients with stable disease (average duration, greater than or equal to 12 months), and five with disease progression were observed. Three patients could not be evaluated due to late deaths as a consequence of their disease. There were two postoperative deaths in the remaining seven patients, one due to drug toxicity and one due to probable cardiac arrhythmia. Pelvic I-P has evolved with the avoidance of laparotomy and increased drug dose. We conclude that hyperthermic I-P for pelvic cancer is a safe, effective procedure and an excellent therapeutic option for patients with persistent pelvic cancer.     

Three-dimensional analysis of pelvic volume in an unstable pelvic fracture

BACKGROUND: A model was developed to predict changes in pelvic volume associated with increasing pubic diastasis in unstable pelvic fractures. METHODS: Intact and postfracture pelvic volumes were calculated in 10 cadavers using computerized axial tomography (CT). The true pelvis was assumed to be either a sphere, a cylinder, or a hemi-elliptical sphere. Using the appropriate equations for calculating the volume of each of these shapes, pelvic volume was predicted and then compared with the measured values. RESULTS: The observed volume changes associated with increasing pubic diastasis were much smaller than previously reported. The mean difference between the measured and predicted volume was 20.0 +/- 9.9% for the sphere, 10.7 +/- 6.5% for the cylinder, and 4.5 +/- 5.9% for the hemi-elliptical sphere. The differences between these means were statistically significant (p < 0.001). CONCLUSIONS: This data suggests that the hemi-elliptical sphere best describes the geometric shape of the true pelvis and better predicts quantitative changes in pelvic volume relative to an increasing pubic diastasis as the radius has little effect on the change in volume. Due to the small changes in volume observed with increasing diastasis, factors other than the absolute change in volume must account for the clinically observed effects of emergent pelvic stabilization.     

Vertical pelvic ring displacement in pelvic ring injury: Measurements in pelvic outlet radiograph and in cadavers

Background:Vertical pelvic ring displacement (VPRD) is a serious injury and needs assessment. Pelvic outlet radiographs are routinely taken. However, relationship of radiographic and actual VPRD is still in question. Thus, measurement of VPRD from pelvic radiographs was studied.Results:Radiographic VPRD from outlet and anteroposterior pelvic views at 10 mm actual displacement were 20.12 ± 1.98 and 4.08 ± 3.76 mm, at 20 mm were 40.31 ± 1.97 and 9.94 ± 7.27 mm and at 30 mm were 58.56 ± 2.53 and 11.29 ± 2.89 mm. Statistical analyses showed that radiographic VPRD from pelvic outlet view is 1.95 times of actual displacement with strong correlation at 0.992 coefficient and strongly significant regression analysis (P < 0.001) with 0.984 of R² value. Whereas, the measurement from anteroposterior pelvic radiograph was not strongly significant.Conclusion:Pelvic outlet radiograph provides efficient measurement of VPRD with 2 times of actual displacement.     

Current concepts of pelvic congestion and chronic pelvic pain.

Chronic pelvic pain in women is a common and disabling illness caused by numerous organic pathologies usually accompanied by varying psychological dysfunctions. Many patients may receive misdiagnosis, misdirected therapies, or do not seek help at all. Pelvic congestion may be responsible for pain in patients without more common diseases, such as endometriosis and pelvic adhesions, among others. Our view of this condition is evolving. In the United States, this medical condition remains controversial. More recent research from the United Kingdom has caused a fresh look at the diagnosis and treatment of chronic pelvic pain produced by pelvic congestion. Potentially, many patients may benefit from a reconsideration of this approach.     

可调式骨盆外固定架治疗不稳定性骨盆骨折

2007年3月～2011年1月,我科应用可调式骨盆外固定架治疗不稳定性骨盆骨折48例,临床效果满意,报道如下。1材料与方法1.1器械开口器和钻孔器(见图1):开口器尖部呈三棱锥样,长约1 cm,较