慢性咽炎患者口腔健康相关生活质量的调查

目的 测评慢性咽炎对患者口腔健康相关生活质量的影响,为临床诊疗提供参考.方法 收集慢性咽炎患者(慢性咽炎组)130例,另外选取362名常规来院进行口腔检查的普通人群(健康常规组)为对照,采用中文版口腔健康程度量表(oral health related impact profile-14,OHIP-14)进行口腔健康情况测评,并记录个体基本情况和专科检查情况.对OHIP-14得分与各健康因素进行Spearman相关分析与线性回归分析.结果 慢性咽炎组OHIP-14总分为(9.52±7.41)分,显著高于健康常规组(7.45±7.90)分,差异主要体现在功能限制、生理性疼痛、心理不适几个方面.Spearman相关分析结果显示OHIP-14得分与患者的年龄(rs=0.238,P=0.01)、咽部不适程度(rs=0.473,P<0.001)和龋失补牙数(rs=0.26,P=0.005)具有相关性.多重线性分析显示OHIP-14得分与咽部不适程度(steβ=0.353,P<0.001)、龋失补牙数显著相关(steβ=0.186,P=0.037),确定系数R2=0.294.结论 慢性咽炎患者总体口腔健康相关生活质量低于普通人群,应采取相应的预防措施改善患者的口腔健康.     

促进农村地区AIDS患者及HIV携带者口腔健康措施的研究

目的 调查农村地区获得性免疫缺陷综合征(AIDS)患者及人类免疫缺陷病毒(HIV)携带者的口腔卫生知识、态度和行为(knowledge,attitude and practice,KAP)现状,评价相应的干预措施对提高其口腔卫生KAP及口腔健康水平的效果.方法 2009年5至8月对安徽省皖北某县4个行政村共82例AIDS患者及HIV携带者采用一对一匿名采集病史和现场口腔检查,对口腔卫生KAP及口腔疾患现状进行基线调查,根据调查结果 实施干预措施,比较干预前后AIDS患者及HIV携带者口腔卫生状况的改善情况及干预效果.结果 干预前82例AIDS患者及HIV携带者口腔卫生状况较差,干预后76例AIDS患者及HIV携带者相关口腔KAP提高,干预前认为"洗牙可以传播AIDS"者占27%(22/82),干预后为54%(41/76)(x2=20.066,P<0.001);AIDS相关口腔疾病患病率明显下降,干预前83%(68/82)的受访者有"牙龈炎",干预后为62%(47/76)(x2=8.852,P=0.003).由主观因素引起的个人口腔卫生及相关的KAP在干预后改善较好,干预前"每次刷牙超过3 min"者占44%(36/82),干预后为59%(45/76)(x2=4.017,P=0.045).结论 农村AIDS患者及HIV携带者口腔卫生KAP状况较差,干预后得到改善,口腔健康水平得到显著提高.

Abstract：

Objective To survey the status of oral cavity hygiene knowledge,attitude and practice (KAP)of rural acquired immunodeficiency syndrome(AIDS)patients and human immunodeficiency virus (HIV)carriers and take corresponding intervention measures to improve the oral health of these patients.Methods From May to August in 2009,the methods of anonymous face to face structured interview and oral examination at the scene were carried out at the baseline in rural AIDS patients/HIV-carriers.According to the results of the survey,intervention measures were taken.The results of the intervention and the oral hygiene status were compared before and after the intervention.Results The oral health status of 82 AIDS patients and HIV-carriers were in poor before the intervention,and the knowledge of AIDS-related oral health of 76 AIDS patients and HIV-carriers was promoted after interventions,"scaling can spread AIDS"were 22 cases(27%),and after the intervention 41 patients(54%)think that can spread(x2=20.066,P<0.001).The oral diseases of related AIDS were decreased dramatically,68 patients(83%)had gingivitis before intervention and 47 cases(62%)after the intervention(X2=8.852,P=0.003).The personal oral cavity hygiene and related oral KAP of AIDS caused by subjective hetors had improved to different extent,"brushing teeth over 3 min at every turn",there were over 36 cases(44%)before intervention and 45 patients after intervention(59%)(X2=4.017,P=0.045).Conclusions The oral hygiene and KAP of AIDS patients and HIV-carriers in rural areas were poor and improved after intervention.     

养阴活血汤联合转移因子治疗原发性舍格伦综合征临床研究

目的 观察养阴活血汤联合转移因子胶囊治疗原发性舍格伦综合征的临床疗效.方法 将136例原发性舍格伦综合征患者分为3组.A组72例,为中西医结合治疗组,患者口服中药养阴活血汤汤剂,同时服用转移因子胶囊;B组32例,为单纯免疫治疗组,口服转移因子胶囊治疗;C组32例,为对症治疗组,患者咀嚼口香糖、口含维生素C以刺激唾液分泌,用0.5％羧甲纤维素滴眼,缓解眼干症状.结果 治疗后A组总有效率97.2％,B组总有效率81.3％,C组总有效率37.5％;3组治疗总有效率比较,A组与B组差异有统计学意义(x2=10.32,P=0.032),A组与C组差异有统计学意义(x2=18.23,P=0.017).治疗后A组口干、眼干症状明显好转,B组症状缓解,C组症状无明显缓解;A组与B组差异没有统计学意义(t=2.16,P=0.062),A组与C组差异有统计学意义(x2=8.63,P=0.031).A组患者经治疗后,血沉、血清IgG明显降低,C组降低不明显;A组与B组差异没有统计学意义(t=1.56,P=0.082),A组与C组差异有统计学意义(t=9.52,P=0.027).结论 养阴活血汤联合转移因子胶囊治疗原发性舍格伦综合征,缓解口干、眼干症状效果显著,有良好的治疗效果.     

口腔干预对牙周炎大鼠动脉粥样硬化影响的研究

目的探讨牙周炎经不同口腔干预处理后对动脉粥样硬化的影响。方法 SD大鼠随机分为3大组,A组:正常对照组,B组:动脉粥样硬化模型组;C组:牙周炎模型组;牙周炎模型建立后,根据口腔干预措施的不同C组再随机2次分为4组,C1自然进程组、C2基础治疗组、C3服药组和C4拔牙组。各组接受相应口腔干预措施。用酶联免疫吸附(ELISA)法,检测干预前、中、后时段,血清hsCRP水平。处死动物后,光镜观察颈动脉血管壁组织的病理变化。结果自然状态无干预的各组在所有取样时间点,与A组相比,B组及C1组的hsCRP含量均显著升高(P0.05),其中,B组的hsCRP含量最高,且含量与C1组之间差异在第3次取样时间点,有统计学意义(P0.05)。进行口腔干预后,与C1组比,各干预组的hsCRP含量均有不同程度的升高,C4组的第2、3次血清hsCRP含量均显著高于C1组(P0.01),C2组在第2次取样时较C1组有下降趋势,但差异无统计学意义。颈动脉血管壁病理切片发现,除A组和C2组未见泡沫细胞形成外,其余各组均可见大量泡沫细胞的形成和聚集,出现动脉粥样硬化的早期病理改变。结论无高血脂存在的SD大鼠,单纯牙周炎任其自然发展或炎症期直接拔牙都可能增加动脉粥样硬化发生风险。牙周基础治疗可能降低动脉粥样硬化的发生风险。     

大块复合树脂联合透明预成冠美学修复乳切牙的临床评价

目的探讨大块复合树脂联合透明预成冠用于患儿乳切牙美学修复的临床评价。方法预先设计临床前瞻性随机对照研究方法,选取入组患者90例(患牙123颗),随机数表法分为A、B、C三组,试验组A组为SF(SonicFill)大块复合树脂联合透明预成冠(30例,患牙41颗),对照组B组为Tetric N-Ceram Bulk Fill大块复合树脂联合透明预成冠(29例,患牙39颗)和C组为3M Z350 XT通用纳米树脂联合透明预成冠(31例,患牙43颗),采用视觉模拟评分法量表(VAS)和改良USPHS标准于术后12个月进行临床效果评价。结果术后12个月,A组的评价指标均优于2B、C组,差异均具有统计学意义,包括:边缘完整性(χ2=10.847,P=0.028),边缘台阶(χ2=7.799,P=0.020),边缘变色(χ2=10.391,P=0.034),表面状态(χ2=11.476,P=0.021);继发龋(χ2=10.447,P=0.034)。A组家长对整体轮廓(χ2=10.238,P=0.037)、形态质地(χ2=11.521,P=0.021)的满意度评价均优于B、C组,差异均具有统计学意义,3组家长对颜色满意程度评价无显著性差异(χ2=0.990,P=0.610)。结论 SonicFill大块复合树脂联合透明预成冠用于乳切牙美学修复短期效果较好,患儿家长满意度较高。     

CO_2激光与氯喹联合治疗口腔扁平苔藓80例报道

目的　评价CO2 激光和氯喹治疗口腔扁平苔藓的效果。方法　随机将 80例口腔扁平苔藓患者分为 3组。A组 2 6例 ,口服磷酸氯喹 ,5 0 0mg/d ,2周后减为 2 5 0mg/d ,共用药 4周。B组 2 5例 ,采用CO2 激光局部照射治疗 ,连续聚焦方式 ,输出功率 5W ,照射时间 5s。C组 2 9例 ,先进行CO2 激光照射治疗 ,功率参数同B组相同 ,治疗后口服氯喹 12 5mg/d ,用药 4周。随访 6月 ,进行统计分析。结果　A、B、C 3组有效率分别为 80 .7%、84.0 %、93.1% ,无显著性差异 ;治愈率分别为 38.5 %、48.0 %、75 .9% ,有显著性差异 (χ2 =10 .82 ,P <0 .0 5 ) ,A组与C组、B组与C组均有显著性差异。结论　CO2 激光局部照射与口服小剂量氯喹联合治疗非糜烂型扁平苔藓 ,可提高治愈率 ,减少药物的不良反应     

互动式集体儿童口腔保健模式效果评价

目的评价互动式集体儿童口腔保健模式的效果。方法采用家长、老师、牙医、儿童一起参与、防与治相结合的互动式集体儿童口腔保健模式，在试验幼儿园开展口腔保健试验2年。结果试验后，对照组患龋率（79．26％）、龋均（4．59），明显高于试验组（70．63％、3．79），两组间差异有统计意义（P〈0．01）。含氟牙膏使用率增加47．8％；家长帮孩子刷牙每天1次的比率增加53．0％。结论采用互动式集体儿童口腔保健模式可以提高幼儿园儿童口腔健康水平。     

麦芽糖醇口香糖对口腔三种致龋菌的抑制作用

目的:探讨麦芽糖醇口香糖对口腔中3 种致龋菌的抑制效果.方法: 将30 名13～15 岁龋易感儿童随机分为3 组,即麦芽糖醇口香糖组(A组)、木糖醇口香糖组(B组)、空白胶母口香糖组(C组).咀嚼口香糖前后共收集2 次牙菌斑,运用平板法进行牙菌斑中细菌培养计数观察咀嚼口香糖前后3 种致龋菌(变链、乳杆、黏放)数量的变化.结果: 与咀嚼前相比,咀嚼口香糖4 周后A、B、C 3 组变链、乳杆、黏放致龋菌数量均呈下降趋势(P<0.001);与C组相比,咀嚼口香糖4 周后A、B 2 组更能显著降低变链数量(P<0.05);3 组间乳杆菌数量和黏放数量的下降无统计学差异(P>0.05).结论:麦芽糖醇口香糖抑制牙菌斑内变链菌数量较为明显,对乳杆菌、黏放菌的抑制作用则不明显.     

正畸改性流动树脂的体外研究

目的:为了增加正畸粘接剂的抗菌性,减少正畸患者的龋白斑发生,现将季铵盐单体甲基丙烯酸十六烷基二甲胺(DMAHDM)以不同浓度梯度加入到流动树脂中作为一种正畸改性粘接剂,以期该种改性粘接剂在满足正畸临床粘接要求的前提下获得更好的抗菌效果.方法:将DMAHDM以质量分数为0％、3％、5％、7.5％加入到3M Z350XT流动树脂中分别记为A组(0％DMAHDM+3M),B组(3％DMAHDM+3M)C组(5％DMAHDM+3M)和D组(7.5％DMAHDM+3M),并在离体牙上粘接托槽.测试托槽剪切粘结强度(shear bond strength,SBS),建立变形链球菌生物膜模型,扫描电镜观察菌斑粘附量,MTT法测得生物膜代谢活性A值来评价改性粘接剂的抗菌性能.结果:抗剪切强度分析,各组间SBS值差异有统计学意义(P=0.001),A组与B组差异无统计学意义(P=0.600),A组与C组、D组差异有统计学意义(P<0.05),C组与D组差异无统计学意义(P=0.530),与A、B组相比,C、D组SBS值下降.抗菌性能的检测,各组菌斑代谢活性(A值)差异有显著性(P=0.000),B、C、D组的抗菌效果均优于A组,C组优于B组,D组优于C组.扫描电镜观察,D组粘接剂的试件表面细菌粘附量最少.结论:在3M Z350XT流动树脂中添加7.5％DMAHDM抗菌剂作为正畸改性粘接剂,但仍能够满足正畸临床粘接的要求且抗菌效果显著,具有一定的临床应用价值.     

磷酸氯喹与多烯酸乙酯胶丸治疗OLP疗效观察

目的 :观察磷酸氯喹与多烯酸乙酯胶丸联合治疗口腔扁平苔癣临床疗效。方法 :180例OLP随机分为试验组和对照组 ,试验组 :用磷酸氯喹与多烯酸乙酯胶丸联合治疗 ;对照组A、B分别仅用磷酸氯喹或多烯酸乙酯胶丸进行治疗 ;结果 :总有效率 :试验组为 86.7% ,对照组A为 71.67% ,对照组B为 68.3 3 % ,试验组与对照组A比较 ,有显著差异 (X2 =4.93 ,P <0 .0 5 ) ,试验组与对照组B比较 ,也有显著差异 (X2 =5 .78,P <0 .0 5 )。二年后复发率 ,试验组为 17.3 1% ,对照组A为 3 8.46% ,对照组B为 45 .16% ,试验组与对照组A比较 ,有显著差异 (X2 =5 .13 ,P <0 .0 5 ) ,试验组与对照组B比较 ,也有显著差异 (X2 =7.5 2 ,P <0 .0 1)。结论 :磷酸氯喹与多烯酸乙酯胶丸联合用药治疗OLP临床效果较满意     

学校口腔健康教育项目的3年效果评价

目的评价以学校为基础的口腔健康教育项目对武汉市学校儿童、母亲和教师口腔健康的促进作用。方法随机选择武汉市洪山区6所小学(3所试验组,3所对照组)参加WHO以学校为基础的3年口腔健康教育项目。使用SPSS/PC 作统计分析,两组间均数的比较采用独立样本的t检验,采用χ2检验评价不同的比例变化。结果试验组儿童的乳恒牙充填(f/F)构成比显著高于对照组(P<0.01),牙龈出血指数与对照组相比显著降低。试验组中,每天至少刷牙2次的儿童比例增加26%,而对照组增加19%(P<0.05);拜访牙医的次数增加的儿童比例高于对照组儿童(P<0.01)。试验组中,母亲每周帮助孩子清洁牙的比例显著增高(P<0.01)。结论口腔健康教育项目对儿童的牙龈健康状况、口腔健康行为以及母亲和教师的口腔健康知识和态度有积极的促进作用。     

椅旁健康教育对慢性牙周炎患者维护期口腔卫生状况的影响

目的探讨椅旁健康教育对慢性牙周炎患者维护期口腔卫生状况的影响。方法 120例慢性牙周炎患者随机分为实验组和对照组,均给予洁治、龈下刮治和根面平整,实验组同时给予全面的口腔健康教育。于基线、基线后1、3、6个月检查Quigley-Hein菌斑指数。采用两组完全随机化设计资料均数的t检验分析所得数据。结果基线、基线后1个月时,两组间菌斑指数差异无统计学意义（t0=1.543,P0=0.1227;t1=1.925,P1=0.063）;基线后3、6个月时,实验组菌斑指数显著低于对照组（t3=19.153,P3=0.001;t6=25.265,P6=0.001）。结论实施全面的口腔健康教育可以显著改善牙周炎患者的口腔卫生状况。     

2种口腔健康教育方式改善中学生口腔卫生状况效果的比较

目的比较2种口腔健康教育方式对中学生口腔卫生状况的改善效果,寻求改善效果较佳的口腔健康教育方式。方法在四川省德阳市市区随机选取3所中学,每个学校均抽取103名12岁学生,男女比例接近1∶1。按学校随机将学生分为3组：老师模式组由口腔医生对老师进行口腔健康知识培训,再由老师对学生上健康教育课,学生在家刷牙;家长模式组由口腔医生对家长进行口腔健康教育培训,通过提高家长的口腔保健意识间接影响学生的口腔健康行为,学生在家刷牙;对照组不采取任何干预措施。对3组学生3个月后的口腔卫生状况改善情况进行比较。结果3个月后老师模式组学生的软垢指数（DI）、牙石指数（CI）和牙龈指数（GI）均明显下降（P<0.05）,家长模式组学生的DI、CI无明显下降（P>0.05）,GI明显上升（P<0.05）。老师模式组学生口腔健康教育后DI、CI、GI指数改善情况优于家长模式组和对照组（P<0.01）。结论以老师和学校为媒介的口腔健康教育模式对中学生口腔卫生状况的改善效果优于以家长为媒介的口腔健康教育模式。老师在口腔健康促进活动中起到了重要的作用。     

Oral health status, salivary flow rate and salivary quality in children, adolescents and young adults with ADHD

Background

Attention deficit hyperactivity disorder (ADHD) is a childhood neurological disorder that presents in 3–7% of school-age children. Studies have shown that children, adolescents and young adults with ADHD are more prone to caries than those without.

Aim

The study investigated a possible relationship between the oral health status of children, adolescents and young adults diagnosed with ADHD, both with and without pharmacological intervention, and the following: salivary flow rate, oral mucosal pH, plaque index (PI), oral hygiene and dietary behaviour.

Study design

DMFT/dmft index (D;d-Decay, M;m-Missing; F;f-Filled,T;t-teeth), plaque index, oral mucosal pH and unstimulated whole salivary flow (USF) were examined in three groups of children, adolescents and young adults: those diagnosed with ADHD with no pharmacological intervention (N = 31), those treated with medications for ADHD (N = 30), and a healthy control group (N = 30). Diet and oral health habits were assessed by means of questionnaires completed by parents.

Results

Mean USF values were 0.72, 0.85 and 1.13 ml/min for participants with ADHD and without medication, with ADHD and with medication, and without ADHD, respectively (p = 0.016). There were no differences in the DMFT/dmft index and in parent reported diet and oral health behaviour between the three groups. Children with ADHD demonstrated a statistically significant higher plaque index (p < 0.05).

Conclusions

The ADHD group, with or without pharmacological intervention, showed higher plaque index and lower USF, but no difference in DMFT/dmft. The ADHD group did not differ from the non-ADHD group in their diet or oral health behaviour as assessed by parent reports.     

潮州市15～17岁学生口腔健康知识及行为调查

目的：探讨潮州市15～17岁学生对口腔健康知识的了解情况及其口腔健康行为，为口腔卫生保健工作提供信息支持。方法采用分层整群随机抽样的方法，按照样本纳入标准抽取潮州市15～17岁学生933名进行问卷调查。所使用问卷参照第四次全国口腔健康流行病学调查问卷，结合本课题研究目的设计。问卷内容包括：人口统计学和社会学资料、口腔健康知识和口腔健康行为。对问卷调查资料进行分析。结果仅13.1%的学生认同“窝沟封闭可保护牙齿”。女生（t=5.198）、父亲受教育程度较高者（t=2.667）口腔健康知识得分较高（P<0.01）。刷牙频率与年龄和性别相关，年龄较大者（c2=23.002）和女生（c2=98.722）每天刷牙2次或以上的比例较高（P<0.001）。75.2%的学生不知道自己使用的牙膏是否含氟，91.5%的学生没有使用过牙线。口腔科就诊经历在性别（c2=16.406）和母亲受教育程度（c2=12.566）方面的差异具有统计学意义（P<0.01）。结论潮州市15～17岁学生口腔健康知识及行为需要积极改善，男生、低年龄组和父母受教育程度低者是重点教育对象。     

多维度口腔清洁干预模式对区域学龄前儿童防龋效果的评价

目的:探讨多维度口腔清洁干预模式对区域学龄前儿童（3~6岁）的防龋效果。方法:于2016年10月随机抽取上海市静安区12所幼儿园600名3~4岁儿童,分为对照组和实验组（每组6所幼儿园300名儿童）。对照组进行常规口腔保健教育,实验组采用多维度口腔清洁干预模式进行干预,随访观察2年,比较2组儿童的口腔清洁行为和患龋状况。采用SPSS 22.0软件包对数据进行统计学处理。结果:实验组儿童在刷牙次数、刷牙时间、正确刷牙方法、含氟牙膏和牙线的使用等方面均显著高于对照组（P<0.01）,并且患龋率和龋均（dmft指数）显著低于对照组（P<0.01）。结论:对于学龄前儿童,采用多维度口腔清洁干预模式,能更好地对儿童和家长口腔卫生知、信、行的改变起到积极有效的作用,从而指导和监控家长对儿童进行有效口腔清洁,降低患龋风险。     

School‐based intervention to promote preadolescents’ gingival health: a community trial

Abstract – Objectives: Evaluation of the effectiveness of a school‐based oral health promotion intervention on preadolescents’ gingival health. Methods: A community trial designed for a 3‐month intervention study in a representative sample of 9‐year‐olds (n = 457) in 16 schools in Tehran, Iran. The schools were randomly assigned to three intervention groups and one control group, each group comprising two boys’ and two girls’ schools. The first group of children (n = 115) received intervention via class work, solving a set of puzzles containing oral health messages, under supervision of their health counsellor. The second group (n = 114), intervention via parents, included an oral health education leaflet and a brushing diary for supervising the child’s tooth‐brushing; the third group (n = 111) received a combination of both these interventions. The control group (n = 117) had no intervention. Effects of the intervention were assessed as changes in dental plaque and gingival bleeding. Improvements in gingival health were recorded when half of the index teeth with plaque at baseline became clean (acceptable oral hygiene) or when all index teeth with bleeding at baseline became healthy (healthy gingiva). Statistical analysis included chi square, anova , t‐test, Number Needed to Treat (NNT) and generalized estimating equations (GEE). Results: At baseline, none of the children were free of plaque and all except for three boys had bleeding. After the trial, acceptable oral hygiene was more frequent in the parental‐aid (P < 0.001) and the combined groups (P < 0.05), and healthy gingiva in both groups (P < 0.001) in comparison with the control group. Outcomes in the class‐work group did not differ from those in the control group. The GEE models confirmed a strong intervention effect on healthy gingiva in both groups where parents were involved: parental‐aid group (OR = 7.7, 95% CI: 2.2–27.7) and combined group (OR = 6.6, 95% CI: 2.0–22.1). In all intervention groups more girls than boys achieved healthy gingiva (OR = 2.5–2.6). Parents’ education showed no impact on the outcome. Conclusions: When a school‐based oral health intervention involves parents it may result in a significant improvement in the gingival health of preadolescents with poor gingival health at baseline.     

山东省1126名小学生口腔现状调查及危险因素分析

目的了解山东省小学生口腔健康状况及龋病危险因素,为采取小学校口腔健康干预措施提供依据。方法根据调查目的设计小学生口腔健康检查表、小学生口腔健康问卷以及家长口腔健康问卷,采用分层随机抽样的方法选择调查班级进行调查。并对调查结果进行多因素分析。结果调查总人数为1126人,男生581人,女生545人,乳牙患龋率为46.84%,龋均为1.46±2.111,恒牙患龋率为12.61%,龋均为0.21±0.630。多因素分析发现小学生患龋和家长受教育程度(P=0.047)、家长对小学生口腔状况的评估(P<0.001)等因素有关。结论应结合调查分析发现的危险因素,有针对性的加强对小学生及家长的口腔健康教育。     

Effectiveness of an oral health education and caries prevention program in kindergartens in China

OBJECTIVES: To evaluate the effect of a 2-year oral health education and caries prevention program implemented in kindergartens in China. METHODS: Seven hundred and thirty-one 3-year-old children were recruited from 10 kindergartens in Miyun County, Beijing, China. The kindergartens were randomly divided into two groups. Oral health education was provided to teachers in the test kindergartens every 3 months. Oral health education sessions were conducted for the test children monthly and for their parents semiannually. Children in the test kindergarten brushed their teeth twice daily with fluoridated toothpaste (1100 ppm F-) in their kindergarten under the supervision of teachers during weekdays. No oral health education session and no supervised tooth brushing activities were carried out in the control kindergartens. A clinical examination of the study children and a questionnaire survey of their parents were conducted at baseline and after a 2-year program. RESULTS: Five hundred and fourteen children remained in the study after 2 years. The mean caries increments of the test group (n = 258) and the control group (n = 256) were 2.47 and 3.56 dmfs, respectively. The reduction in dmfs increment was 30.6% (P = 0.009). At the evaluation, a significantly higher percentage of children in the test group than in the control group reported brushing their teeth twice a day (87.6% vs. 69.0%; P < 0.001). Parents of children in the test group had better oral health knowledge and attitude than the parents of children in the control group. CONCLUSION: This oral health education program was effective in establishing good oral health habits among preschool children and in increasing oral health knowledge of their parents, in conjunction with supervised daily tooth brushing with fluoridated toothpaste, which could reduce the development of new dental caries in preschool children in China.