强脉冲光联合Q开关倍频Nd:YAG 532nm激光治疗面部雀斑疗效观察

目的:观察强脉冲光联合Q开关倍频Nd:YAG 532nm激光治疗面部雀斑的临床效果。方法:选取笔者医院2017年5月-2019年5月收治的126例雀斑患者,随机分为观察组和对照组,每组63例。对照组采用强脉冲光治疗,观察组采用强脉冲光联合Q开关倍频Nd:YAG 532nm激光治疗,观察两组治疗后的临床效果。结果:观察组临床总有效率明显高于对照组(χ^2=12.86,P<0.01),观察组治疗总次数明显低于对照组(t=3.928,P<0.05),复发率也明显低于对照组(χ^2=4.189,P<0.05),患者对治疗满意度明显高于对照组(χ^2=13.945,P<0.01),两组不良反应发生率无明显差异(χ^2=0.099,P>0.05)。结论:强脉冲光联合Q开关倍频Nd:YAG 532nm激光治疗雀斑复发率低、治疗次数少、安全性高,临床效果显著,值得在临床上推广使用。     

自体疣植入联合Q开关Nd:YAG激光治疗扁平疣疗效分析

目的:观察自体疣植入联合Q开关Nd:YAG激光治疗扁平疣的临床疗效。方法:将125例扁平疣患者随机分成治疗组80例和对照组45例,治疗组先行自体疣植入,后期使用Q开关532nm Nd:YAG激光治疗;对照组单外用咪喹莫特乳膏治疗,观察两组疗效。结果:治疗组痊愈率为81.0%,总有效率为97.5%,对照组痊愈率为44.0%,总有效率为75.5%,两组疗效比较,差异均有统计学意义(P0.01)。结论:自体疣植入联合Q开关Nd:YAG激光治疗扁平疣疗效好、复发率低,值得临床推广应用。     

Q开关Nd:YAG激光治疗文身329例临床观察

目的:观察Q开关Nd:YAG激光治疗文身的临床效果及并发症。方法:用Q开关Nd:YAG激光治疗不同部位、颜色、类型的文身,根据颜色选择1064nm、532nm或1064nm&532nm复合波长,根据深浅选择不同能量密度。结果:经过2～5次治疗,治愈率达60%,显效占38%,有效占2%。结论:Q开关Nd:YAG激光治疗文身无明显副作用,不留瘢痕,痛苦小,恢复快,治愈率高。     

Q开关Nd:YAG激光治疗面部色素增加性病变疗效分析

目的:观察Q开关Nd:YAG激光治疗面部色素增加性皮肤病的临床疗效及副反应。方法:使用Q开关Nd:YAG激光治疗145例色素增加性皮肤病患者。雀斑、咖啡斑和脂溢性角化病采用波长532nm,太田痣和文身采用波长l 064nm。结果:145例患者经治疗后,色素性病变逐渐消退,其中文身、雀斑、脂溢性角化病疗效较为显著。结论:Q开关Nd:YAG激光治疗色素增加性皮肤病疗效好,安全有效,是一种无创的治疗方法。     

水光注射三联疗法联合大光斑低能量Q开关1064nm Nd:YAG激光治疗黄褐斑疗效观察

目的:评价水光注射三联疗法联合大光斑低能量Q开关1 064nm Nd:YAG激光治疗黄褐斑的疗效。方法:选取2013年1月-2016年12月在笔者医院门诊就诊的黄褐斑患者60例,随机分为治疗组和对照组,每组各30例。治疗组:接受水光注射三联疗法(玻尿酸2.5ml,氨甲环酸3ml,还原型谷胱甘肽1.5ml)3次,每2个月1次;Q开关1 064nm Nd:YAG激光(光斑直径6~7mm,能量密度3.0~4.06J/cm2)治疗3次,于每次水光治疗后1个月进行,两种治疗交替进行;对照组:仅接受Q开关1 064nm Nd:YAG激光治疗,每月1次,共6次。结果:治疗组有效率83.3%,对照组有效率56.7%,两组差异有统计学意义(P0.05),未见明显不良反应。结论:水光注射三联疗法联合大光斑低能量Q开关1 064nm Nd:YAG激光治疗在很大程度上改善皮肤肤质,淡化黄褐斑,效果明显优于单用Q开关1 064nm Nd:YAG激光治疗,且安全性佳。但水光注射三联疗法联合大光斑低能量Q开关1 064nm Nd:YAG激光治疗对黄褐斑的改善程度与治疗次数、术后肌肤的修复及保养密不可分。     

低能量Q开关Nd:YAG激光联合胶原贴敷料治疗面部寻常性痤疮疗效观察

目的:观察低能量Q开关Nd:YAG激光联合胶原贴敷料治疗面部寻常性痤疮的临床疗效。方法:98例寻常性痤疮患者,采用半侧面部对照观察,分为两组。治疗组:左侧面部,先用粉刺针清除皮损,再采用低能量Q开关Nd:YAG激光联合使用胶原贴敷料治疗;对照组:右侧面部,采用低能量Q开关Nd:YAG激光联合使用胶原贴敷料治疗。激光治疗两周1次,6次为1个疗程。98例患者均进行1个疗程的Q开关Nd:YAG激光治疗,观察治疗后皮损改善的效果及不良反应。结果:治疗组痤疮皮损改善有效率(90.82%)明显高于对照组(71.43%),两组差异有统计学意义(P0.01),两组患者在激光治疗后均配合使用胶原贴敷料,能明显缓解患者皮肤的灼热感及干燥敏感。结论:低能量Q开关Nd:YAG激光联合胶原贴敷料治疗面部寻常性痤疮,面部先用粉刺针清除皮损,联合治疗效果确切,且不良反应发生率低。     

Q开关Nd:YAG 1064nm激光联合口服氨甲环酸片治疗黄褐斑疗效观察

目的:观察Q开关Nd:YAG 1064nm激光联合口服氨甲环酸片治疗黄褐斑的临床疗效。方法:2011年7月～2012年10月,选取门诊就诊的黄褐斑患者30例,随机分为治疗组和对照组,每组各15例。治疗组:接受Q开关Nd:YAG 1064nm激光联合口服氨甲环酸片治疗;对照组:仅接受Q开关Nd:YAG激光治疗。每次治疗后都辅以维C导入及胶原蛋白修复面膜外敷,每2周治疗1次,10次为1个疗程;治疗组同时口服氨甲环酸片,每日2次,每次250mg,连服半年。1个疗程结束即评判疗效,治疗期间及1个疗程结束后3个月观察疗效及不良反应。结果:治疗组总有效率为93.3%,对照组为73.4%,两组疗效比较,差异均有统计学意义(P<0.05),未见明显不良反应。结论:Q开关Nd:YAG 1064nm激光联合口服氨甲环酸片治疗黄褐斑优于单用Q开关Nd:YAG激光治疗,且不良反应少,适合临床应用。     

Q开关Nd:YAG 1064nm激光联合中药面膜治疗黄褐斑疗效观察

目的:观察Q开关Nd:YAG 1 064nm激光联合中药面膜治疗黄褐斑的临床疗效。方法:对符合黄褐斑临床诊断的105例患者均使用Q开关Nd:YAG 1 064nm激光治疗,其中治疗组53例加用中药面膜外敷,对照组52例单纯1 064nm激光治疗。连续治疗3个周期,评价临床疗效及色素沉着的发生率。结果:治疗结束后,治疗组总有效率92.45%,明显高于对照组的76.92%。随访1年后,治疗组总有效率87.79%明显高于对照组69.23%,有显著性差异(P0.05);治疗组色素沉着发生率3.77%明显低于对照组17.31%(P0.05)。结论:Q开关Nd:YAG 1 064nm激光联合中药面膜治疗黄褐斑疗效显著,不良反应少,值得临床推广应用。     

Q开关Nd：YAG激光治疗色素性皮肤病5000例疗效观察

目的：观察Q开关Nd：YAG激光治疗色素性皮肤病的疗效、影响因素及副反应。方法：使用Q开关Nd：YAG激光治疗色素性皮肤病患者5000例,浅表性色素损害雀斑、咖啡斑和老年斑采用Q532nm波长,太田痣和文身采用Q1064nm波长。结果：本组患者经1～6次治疗,总有效率达96．14％,术后出现暂时性色素沉着269例（5．38％）,无瘢痕发生。结论：Q开关Nd：YAG激光治疗色素性皮肤病疗效较好,安全性高。     

复方杏仁面膜联合低能量Q开关Nd:YAG激光治疗黄褐斑对患者黑色素沉积的影响

目的:分析复方杏仁面膜联合低能量Q开关Nd:YAG激光治疗黄褐斑对患者黑色素沉积的影响.方法:选择2017年7月-2019年1月于笔者医院皮肤科收治的102例黄褐斑患者,随机分为对照组和观察组,每组51例.对照组采用低能量Q开关Nd:YAG激光治疗,2次/周;观察组在对照组的基础上加用复方杏仁面膜治疗,2次/周.两组均...     

Use of Onion Extract, Heparin, Allantoin Gel in Prevention of Scarring in Chinese Patients Having Laser Removal of Tattoos: A Prospective Randomized Controlled Trial

BACKGROUND: With rapid advancement in cutaneous laser therapy, Q-switched lasers have become the standard treatment for tattoo removal. The longer wavelength Q-switched Nd:YAG laser is used when removing tattoos in darker skin patients to avoid scarring and permanent pigment changes. Nevertheless, the local experience revealed that nearly 25% of the Chinese patients developed scarring. Meanwhile, multiple clinical studies have shown that Contractubex gel (Merz Pharma, Frankfurt, Germany) was effective in the treatment and prevention of hypertrophic scars and keloids. OBJECTIVE: To evaluate the efficacy of Contractubex gel in the prevention of scarring after laser removal of tattoos in Chinese patients. METHODS: A total of 120 Chinese patients with 144 professional blue-black tattoos were recruited into the study. They were randomly assigned into the Contractubex group or the control group. All patients were treated with a QS 1,064-nm Nd:YAG laser using a 3-mm spot size, a 10-Hz repeat rate, a pulse duration of 6 nanoseconds, and fluences that ranged from 3.6 to 4.8 J/cm2 (mean fluence, 4.2 J/cm2). The treated areas were assessed 3 months after the last treatments for clinical clearance and complications. RESULTS: Fifty-two patients with 61 tattoos in the Contractubex group were able to achieve a mean clearing rate of 82.3+/-11.6%. There were 7 tattoos in 7 patients that developed scarring, 4 patients had permanent hypopigmentation, and 3 patients had transient hyperpigmentation. In contrast, 55 patients with 68 tattoos in the control group had a mean clearing rate of 80.4+/-11.3%. Among them, 16 tattoos in 14 patients developed scarring, 4 patients had permanent hypopigmentation, and 5 patients had transient hyperpigmentation. Although there was no significant difference in age, sex, fluence, treatment session, and clinical clearance between the two groups, the Contractubex group had a statistically significantly lower rate of scarring than the control group (p<.05). CONCLUSION: Contractubex gel is effective in scar prevention in Chinese patients having laser removal of tattoos.     

Q-开关Nd:YAG激光1064nm联合还原型谷胱甘肽治疗黄褐斑的临床疗效分析

目的:探讨Q-开关Nd:YAG激光1 064nm联合还原型谷胱甘肽治疗黄褐斑的临床疗效。方法:选取黄褐斑患者62例。将患者随机分为治疗组及对照组各31例。对照组单纯应用Q-开关Nd:YAG激光1 064nm治疗;治疗组在应用Q-开关Nd:YAG激光1064nm治疗的同时联合应用还原型谷胱甘肽(GSH)0.9g,加入生理盐水250ml静滴,每日1次,每次激光治疗后连续点滴5日。结果:治疗组基本治愈12例,显效16例,好转3例,无效0例,总有效率为90.3%,对照组基本治愈9例、显效13例、好转7例、无效2例,总有效率70.9%,两组疗效比较(P0.05),差异有统计学意义。结论:Q-开关Nd:YAG激光1 064nm联合还原型谷胱甘肽治疗黄褐斑疗效确切,安全性高,无明显副作用,是一种安全、有效的治疗方法。     

Q开关激光治疗双侧面部获得性太田痣样斑287例疗效分析

目的：比较Q开关紫翠宝石755nm激光、Nd：YAG1064nm激光和倍频Nd：YAG532nm激光对双侧获得性太田痣样斑的治疗效果和副作用。方法：运用Q开关紫翠宝石755nm激光、Nd：YAG1064nm激光和倍频Nd：YAG532nm激光分别对287例患者进行治疗。结果：经过1～13次治疗后,痊愈140例,显效66例,有效59例,无效22例,总有效率71.8%,总治愈率48.8%。倍频Nd：YAG532nm激光治疗起效快而副反应明显,Q开关紫翠宝石755nm激光和Nd：YAG1064nm激光起效慢但副反应轻微。结论：三种Q开关激光均能有效治疗双侧获得性太田痣样斑,长程低能量的Q开关紫翠宝石755nm激光和Nd：YAG1064nm激光因副反应轻微更适合美容患者的需要。     

Q开关Nd:YAG激光联合强脉冲光治疗雀斑临床观察

目的:寻找临床上对雀斑的最佳治疗方法。方法:采用Q开关倍频Nd:YAG激光和强脉冲光联合治疗雀斑,进行疗效观察,并与继往单纯采用Q开关激光治疗的病例进行疗效对比研究。结果:单纯用Q开关激光治疗的224例雀斑患者,痊愈178例(79.5%),采用Q开关激光联合强脉冲光治疗的52例雀斑患者,痊愈50例(96.2%)。两组痊愈率之间差异有显著性。结论:采用激光与强脉冲光联合治疗雀斑疗效好、副作用小,值得临床推广。     

调Q Nd：YAG脉冲激光和二氧化碳激光治疗面部色素痣疗效对比观察

目的：观察调QNd：YAG脉冲激光和二氧化碳激光治疗面部色素痣的临床疗效与美容效果。方法：将315例门诊患者随机分成两组：甲组167例,采用调QNd：YAG脉冲激光治疗,波长1064nm,光斑2～3mm,能量密度4。0～4．2J／cm2,频率1～2Hz,点射至肉眼观无黑色组织;乙组148例,采用二氧化碳激光治疗,连续扫射至肉眼观无黑色组织,观察皮损祛除与瘢痕情况。结果：甲组治疗有效率97．97％,乙组治疗有效率97．00％,两组相比P〉0．05,没有统计学差异;甲组瘢痕出现率64．07％,乙组瘢痕出现率为75．00％,两组瘢痕出现率比较,P〈0．05,有统计学差异;甲组中,不同疹型间痊愈率和瘢痕出现率比较均P〈0．05,有统计学差异。结论：调ONd：YAG脉冲激光治疗面部色素痣与二氧化碳激光相比,美容效果优于后者;调QNd：gAG脉冲激光对斑疹型色素痣的疗效优于丘疹型色素痣。     

强脉冲光联合Q开关倍频Nd：YAG激光治疗婴幼儿血管瘤临床观察

目的：观察强脉冲光联合Q开关倍频Nd：YAG激光治疗婴幼儿血管瘤的疗效和安全性。方法：选择100例1岁以内婴幼儿血管瘤患者,随机分为治疗组和对照组,治疗组使用IPL和Q开关倍频Nd：YAG激光联合治疗,对照组仅使用IPL治疗,每3周治疗1次,5次为1个疗程。疗程结束后分析疗效及安全性,并行统计学处理。结果：治疗组皮损痊愈率明显高于对照组（P〈0.05）,总有效率两组间无明显差异（P〉0.05）。两组不良反应均轻微,未见明显色素沉着、色素减退及瘢痕形成。结论：IPL联合Q开关倍频Nd：YAG激光治疗婴幼儿血管瘤安全、有效,临床效果优于单独IPL治疗。     

Successful Treatment of a Cosmetic Tattoo Using a Combination of Lasers

BACKGROUND: Cosmetic tattoos are becoming more popular and are often composed of several colors. Tattoo pigments containing ferric oxide and titanium dioxide can change to a blue-black color after exposure to Q-switched lasers that can be permanent. OBJECTIVE: Using a patient who presented with rouge tattoos on the cheeks as an example, we describe a useful approach to laser treatment of cosmetic tattoos. METHODS: Test areas were done with the Q-switched Nd:YAG at both 532 and 1064 nm and with the pulsed-dye laser at 595 nm. RESULTS: Although an immediate blue-black color change occurred after treatment with the Nd:YAG at 532 and 1064 nm, sequential treatments at 1064 nm produced a near complete clearance of the tattoos. The pulsed-dye laser was used to remove subtle pink tones. CONCLUSION: Performing small test areas before complete treatment and using several laser wavelengths throughout the course of therapy are essential to the successful treatment of cosmetic tattoos.     

调Q开关Nd：YAG激光治疗165例颧部褐青色痣疗效观察

目的：观察调Q开关Nd：YAG激光治疗颧部褐青色痣的临床疗效和安全性。方法：应用Q开关Nd：YAG激光治疗颧部褐青色痣患者165例,选用波长1064nm,能量密度4.5～6.0J/cm2,光斑直径3mm,频率1～10Hz;532nm波长能量密度为1.8～2.2J/cm2,光斑直径3mm,频率1～10Hz,共治疗2～5次,术后3个月复诊判定疗效和不良反应。结果：共治愈45例,平均治疗2.6次,总有效率74.1%。术后发生色素沉着89例,无瘢痕发生。结论：调Q开关Nd：YAG激光治疗颧部褐青色痣疗效好,安全性高,不良反应较轻。     

Q开关Nd∶YAG激光两种治疗参数治疗颧部褐青色痣的疗效比较

目的：用Q开关Nd∶ YAG激光的两种不同治疗参数治疗颧部褐青色痣,比较两种治疗参数的疗效及安全性差异.方法：颧部褐青色痣患者52例,采用Q开关Nd∶ YAG激光的低能量大光斑参数（A组）治疗22例,常规高能量参数（B组）治疗30例,治疗后以色素斑片的面积大小、色度变化评价疗效.统计患者的疼痛度、停工期及并发症发生情况.结果：B组治疗后色素斑面积减少及色度减少较A组明显,疗程缩短,但停工期更长,且并发症比A组增多,两者差异具有统计学意义.结论：两种不同治疗参数均可用于治疗褐青色痣,用常规高能量参数治疗效果更为显著,但患者治疗时疼痛明显,术后停工期长,且有局部色素沉着;而低能量大光斑参数疼痛轻微,停工期较短,疗效相对稍差.