脑出血并发神经源性肺水肿24例分析

正重症脑出血患者常引起急性肺水肿、胸腔积液,病情凶险,治疗困难,死亡率高,临床上将排除心脏、肺部、肾脏疾病原因而由中枢神经系统疾病引起的急性肺水肿称为神经源性肺水肿(neurogenic pulmonary edema,NPE)。我院神经外科2012年3月至2016年3月住院治疗的共129例脑出血患者,其中并发神经源性肺水肿24例。回顾性研究NPE患者的临床诊断治疗,对NPE患者血糖、降钙素原、胸部CT等变化情况与治疗、预后进行总结分析,现报告如下。     

非典型神经源性肺水肿的临床分析

目的探讨非典型神经源性肺水肿（NPE）的临床诊治特点。 方法对2006年1月至2015年12月期间承德钢铁集团有限公司职工医院神经外科收治的颅脑损伤及脑出血患者中4例并发早期非典型NPE的诊治进行回顾性分析。 结果在颅脑损伤及脑出血患者中4例早期非典型神经源性肺水肿,早期发现并及早进行机械辅助通气等综合治疗,4例患者均治愈出院。 结论对非典型NPE及早发现并及时辅助通气等综合治疗会收到较好效果。     

重型颅脑损伤合并神经源性肺水肿的早期诊治

重型颅脑损伤后并发的神经源性肺水肿（neurogenie pulmonarl edema，NPE）起病急，进展快，预后差，早期诊断和治疗是提高抢救成功率的关键。我们自1995-10～2005-06共收治NPE患者11例，结合临床及文献报告如下。     

重型颅脑损伤并发神经源性肺水肿19例临床分析

重型颅脑损伤指由于某种暴力作用而对脑部造成的严重创伤,包括头部软组织损伤、颅骨骨折和脑损伤［1］。神经源性肺水肿（NPE）是指在无原发性心、肺等疾病情况下由于各种原因所致的突发性颅内压增高而引起的急性肺水肿［2-3］。重型颅脑损伤之后出现NPE非常危险,由于这种情况发病时间短、病情发展快,病死率非常高,受到医学界的广泛关注。本院2010-06-2012-06收治重型颅脑损伤后并发N PE患者19例,现报道如下。     

神经源性肺水肿24例临床报告

现将我院2001-07～2005-02经CT证实的脑出血、大面积脑梗死合并神经源性肺水肿（NPE）患者24例,报告如下。     

神经源性肺水肿15例临床分析

由颅脑损伤或中枢神经系统其它疾病引起的肺水肿称之谓神经源性肺水肿(neurogenic pulmonary edema，NPE)或中枢性肺水肿，临床并不少见。本病起病急骤，治疗困难，死亡率高达90％。1996-01～2003-01我科共收治15例，现报告如下。     

神经源性肺水肿临床诊治探讨(附17例报告)

由颅脑损伤或中枢神经系统其它疾病引起的呼吸困难,血氧饱和度下降,肢端紫绀等症,临床称之为神经源性肺水肿或中枢性肺水肿（NPE）。此病发病急骤,治疗棘手和死亡率高,为了提高对此病的认识和救治生存率,回顾总结我们1999年以来的病例资料,复习文献作如下报告。     

血必净对颅脑外伤后神经源性肺水肿患者肺功能及血浆TNF-α、IL-6水平的影响

目的 探讨血必净注射液对重型颅脑损伤引起的神经源性肺水肿患者(NPE)肺功能及血浆肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)水平的影响.方法 将38 例NPE 患者随机分为治疗组和对照组,分别检测两组治疗前、治疗后1 d、4 d、7 d 的血浆TNF-α、IL-6 水平.结果 4 d、7 d 血浆TNF-α、IL-6 水平与对照组比较有显著降低(P ＜0.01).结论 血必净注射液对重型颅脑损伤后神经源性肺水肿(NEP)患者的肺功能有一定的保护作用.     

神经源性肺水肿15例临床分析

由颅脑损伤或中枢神经系统其它疾病引起的肺水肿称之谓神经源性肺水肿 (neurogenic　pulmonary　edema ,NPE)或中枢性肺水肿 ,临床并不少见。本病起病急骤 ,治疗困难 ,死亡率高达 90 %〔1〕。 1996-0 1～ 2 0 0 3 -0 1我科共收治 15例 ,现报告如下。1　临床资料1 1　一般资料　本组患者 15例 ,男 11例 ,女 4例 ,平均年龄40 2岁 ,其中儿童 5例 ,成人 10例。1 2　发病原因　除 1例自发性脑出血外 ,其它病例均继发于颅脑损伤或开颅术后 ,其中颅脑损伤后 11例 ,开颅术后 3例。损伤类型包括 :硬膜外血肿 3例 ,硬膜下血肿合并脑挫裂伤 10例 ,弥…     

重型颅脑创伤并发神经源性肺水肿34例分析

重型颅脑创伤患并发的神经源性肺水肿(neurogenic pulmonary edema．NPE)为非心源性的暴发性肺水肿，起病急骤，病情凶险，患多预后不良，病死率极高。我院自1994年12月-2002年12月共收治重型颅脑创伤并发神经源性肺水肿患34例，现对其治疗经过及预后进行分析。     

Treatment with rituximab in patients with polyneuropathy with anti-MAG antibodies

Journal of Neurology -     

Factors associated with satisfaction with care among patients with epilepsy

OBJECTIVE: The purpose of the work described here was to determine those variables associated with satisfaction with care among patients with epilepsy. METHODS: We interviewed patients followed at a tertiary epilepsy center. Predictor variables included age, gender, race, education, income, insurance, seizure frequency, and Quality of Life in Epilepsy-10 inventory (QOLIE-10) results. Target variables were the subscales of the Short Form Patient Satisfaction Questionnaire (PSQ-18). We used univariate analysis to identify those variables significantly associated with the subscales and multiple linear regression to determine those independently significant. RESULTS: The study population comprised 193 patients. Lower education and better QOLIE-10 scores were independently associated with general satisfaction with care. The mental health scale was associated with general satisfaction with care. Lower educational level was the only variable independently associated with patient satisfaction with communication, the financial aspect of care, and time spent with physician. CONCLUSION: Lower educational level and better quality of life are the main variables associated with higher general satisfaction with care among patients with epilepsy.     

Children with ADHD and motor dysfunction compared with children with ADHD only

The purpose of this study was to identify group differences in children with attention-deficit-hyperactivity disorder and motor dysfunction (ADHD-MD) and ADHD only, and to evaluate the medication responsiveness of ADHD-MD. Sixty-three children (49 males and 14 females; mean age 9 years 10 months, SD 2 years 10 months) underwent a triple blind, placebo-controlled crossover study evaluating two dose levels of methylphenidate (0.3 mg/kg and 0.5 mg/kg [corrected], twice daily) and placebo. Forty-nine trials were completed. Nineteen were children with ADHD-MD, 44 had ADHD only. Behavior and functioning were assessed at home and at school. Treatment effects were assessed using the Abbreviated Symptom Questionnaire for Parents and Teachers. Children with ADHD-MD were more likely to have severe ADHD-combined type and other neurodevelopmental and behavioral problems. Both groups of children had a linear dose response to medication (placebo, low, high) and there was no evidence of a group by dose interaction or an overall group effect at home or school. The lack of group effect suggests that these children responded to medication like the other subgroups.