上颌窦牙瘤1例报道

患者女,50岁.1年前发觉左侧面部肿痛,口服消炎药(药名及用量不详),治疗1周后局部肿痛消退,此后未复发.来我院就诊前2周又觉左侧面部肿痛,口服阿奇霉素治疗1周后局部肿痛减轻,但未完全消退.即来我院就诊,查体示左侧面部隆起、轻压痛、无乒乓球样感.鼻腔检查见双侧下鼻甲肥大,鼻道有少许脓性分泌物,未见新生物,鼻腔内侧壁无内移;口腔检查见左上第一、二前磨牙及第一、二、三磨牙缺失,第一、二磨牙对应牙槽骨处隆突、质硬、表面黏膜正常;鼻窦瓦氏位片示左上颌窦腔内有一3 cm×5 cm密度增高影像,边界清、上颌窦腔密度增高;鼻窦螺旋CT检查示左上颌窦腔后下壁有3 cm×5 cm×3cm高密度影像,高于骨质,局部CT值接近牙釉质.初步诊断为上颌窦牙瘤.     

上颌窦纤维血管瘤1例CSCD

纤维血管瘤在耳鼻咽喉科多发生于鼻咽部,其发生在上颌窦者很少,近期我科室诊治上颌窦纤维血管瘤1例,现报道如下。1临床资料患者,男,35岁。因左面部肿胀感7个月余,2016年10月8日于我科门诊就诊,门诊医师查体见左侧鼻腔新生组织,触之易出血,行鼻窦冠状位CT检查示左上颌窦、筛窦软组织影（图1A）,诊断为鼻腔鼻窦肿物（左）,建议入院治疗。入院行常规查体,并行鼻窦MRI检查示左侧上颌窦窦腔扩大,内可见片状混杂信号改变,     

上颌窦黏液瘤1例

1临床资料患者,男性,14岁,以左侧上颌窦根治术后2年,左面部肿胀1个月收治入院。患者2年前因左面部肿胀于当地行左上颌窦根治术,术后病理为梭形细胞肿瘤,伴黏液变性。1个月前无明显诱因再次出现左侧面部肿胀,无面麻,牙痛,张口困难,视力障碍,无头痛、发热等其他不适。既往体健。查体：全身一般情况可。左面部稍隆起,表面皮肤无改变,局部无明显触压痛。张口无受限,牙齿排列尚整齐。左鼻腔外侧壁稍膨隆,鼻甲形态尚可。浅表淋巴结无肿大。2009年1月鼻窦CT检查（图1）。     

干酪性上颌窦炎伴鼻息肉一例

患者男，36岁，因左侧鼻塞、流涕、头痛1年就诊。间断左侧眼眶疼，曾有左眼视力下降，于某院就诊，诊断为“角膜炎”，给予对症治疗，已治愈。就诊时已在外院作鼻窦CT检查，示左侧鼻腔与左侧上颌窦已融为一个大腔，鼻腔外侧壁、上颌窦内侧壁已破坏，左侧鼻腔、上颌窦、筛窦、额窦均可见低密底影（图1）。     

上颌窦海绵状血管瘤误诊1例报告

患者。男，24岁，因涕中带血丝伴左侧持续性鼻塞2年人院。查体见鼻黏膜慢性充血，左侧下鼻甲慢性充血肥厚，对收敛剂不敏感，左侧中鼻道见大量脓性分泌物，吸净后见中鼻道拥挤，鼻腔未见新生物，鼻窦区无压痛。鼻窦水平位CT示左侧上颌窦、筛窦内软组织影，CT值为4 Hu，上颌窦内密度不均匀，CT诊断为左侧筛窦囊肿、左上颌窦炎症、左上颌骨根尖囊肿。人院后行鼻窦冠状位CT检查，示左侧上颌窦、     

空窦综合征1例

1病例报告患者,男,39岁,因左侧鼻腔通气不畅1年于2011年12月26日入院。行鼻窦CT检查发现左侧鼻腔鼻窦占位病变,于2011年12月28日全身麻醉行鼻内镜下鼻腔肿物切除加筛窦、上颌窦、额窦开放手术。术后病理检查示内翻性鳞状上皮乳头状瘤。患者术后顺利出院,定期门诊复诊,自诉偶有左侧内眦处疼痛不适,未在意。2012年10月23日患者于我科门诊复查鼻内镜发现左侧中鼻道新生物（图1）,于2012年12月28日第2次入院,     

鼻腔软骨瘤1例

患者 ,男 ,1 2岁。右侧鼻腔流脓涕 3年 ,鼻部、面部肿胀 1年 ,初疑是“感冒”所致 ,经治疗后未见好转 ,继之鼻阻、流脓涕加重 ,无头昏、头痛及出血等症状。 1年后发现右侧鼻腔肿物 ,逐渐长大 ,鼻外部及右面部肿胀 ,以鼻腔肿瘤性质待查收入院。检查 :右侧鼻背、鼻根及右面部隆起 ,皮肤无发红及压痛。右侧鼻腔内可见淡红色肿物 ,质地中等 ,活动度差 ,鼻中隔明显左偏。软腭无下塌 ,唇龈沟存在 ,无隆起 ,右侧眶下缘清楚。华氏位摄片示右上颌窦炎症改变 ,肿块位于鼻腔内。于 1 993年 7月 2 1日在局麻下经鼻前庭、鼻腔径路行右侧鼻腔肿瘤摘除术。…     

上颌窦胆脂瘤1例

患者,女,16岁,主因左侧鼻塞、脓涕、头痛20 d,伴左侧面颊部红肿,左侧上列牙痛入院.查体:鼻黏膜充血,鼻腔外侧壁内移,中鼻道脓性分泌物,无眼球移位,无复视,左面颊部红肿,压痛明显.鼻窦CT示:左侧上颌窦密度增高,上颌窦外侧壁骨质破坏,右侧上颌窦黏膜轻度肥厚,筛窦、蝶窦及额窦未见异常(图1).     

上颌窦破骨巨细胞样平滑肌肉瘤1例并文献复习

平滑肌肉瘤（Leiomyosarcoma）常见于子宫、胃肠道腹膜后腔[1~3],是由平滑肌细胞或向平滑肌分化的间充质细胞组成的恶性肿瘤,发生在上颌窦者极为少见。本文报道1例发生在上颌窦且含有较多破骨巨细胞的平滑肌肉瘤。1病例报告患者,男,5 6岁,因右侧渐进性鼻塞2个月就诊。门诊检查见右侧鼻腔外侧壁内移,中下鼻道向内膨隆明显,颌面部无隆起,无压痛,视力及眼球活动正常,张口不受限,硬腭无破坏及塌陷。鼻窦CT示：右上颌窦占位性病变,上颌窦内壁骨质破坏,     

上颌骨恶性纤维组织细胞瘤1例

患者,女,45岁。主诉因左侧面部肿胀伴头疼2年余而来院求治。2年前因头疼,流黄涕,鼻塞,曾在当地医院就诊,X线摄片诊为左上颌窦炎。上颌窦穿刺未冲洗出脓性分泌物,未经任何治疗。后左面部渐开始肿胀,局部皮肤麻木,鼻塞加重,涕中带血,并伴有左上牙痛,于1992年2月13日入院治疗。检查:左侧上颌骨壁隆起,有一固定的硬性肿物;眼眶下缘未侵及,眼球无突出,运动正常;左侧鼻腔内无新生物,张口不受限;叩痛,左龈颊沟膨隆质硬,硬腭未见异常改变。鼻窦X线片示左上颌窦混浊,眶下缘骨质     

原发性甲状腺淋巴瘤的诊治研究进展[综述]

原发性甲状腺淋巴瘤（primary thyroid lymphoma,PTL）是罕见的甲状腺恶性肿瘤,其常见的病理亚型包括弥漫性大B细胞淋巴瘤（diffuse large B-cell lymphoma,DLBCL）和黏膜相关淋巴组织淋巴瘤（mucosa-associated lymphoid tissue lymphoma,MALT）,临床很难仅靠细针穿刺细胞学检查和常规组织病理确定其病理亚型,免疫组化和流式细胞仪有助于PTL的诊断。本文就近年来PTL的诊断、治疗和预后研究进展做一综述。     

Synchronous,primary, diffuse,large b‐cell lymphomas involving the ethmoid sinus and epiglottis: A rare clinical entity

Non‐Hodgkin's lymphoma (NHL) affecting the ethmoid sinus and epiglottis is uncommon. Furthermore, synchronous NHLs involving the ethmoid sinus and epiglottis are extremely rare and have not been reported previously. This article reports synchronous, primary, diffuse, large B‐cell lymphoma (DLBCL) arising in the ethmoid sinus and epiglottis, which was successfully treated by immunochemotherapy. A careful examination of the head and neck is necessary to determine the existence of multiple synchronous primary tumors, because primary synchronous occurrence of DLBCL in the head and neck is unusual and can impact the prognosis adversely. Laryngoscope, 2013     

Primary diffuse large B-cell lymphoma of the Larynx

The larynx is a rare site of extranodal non-Hodgkin lymphoma (NHL), accounting for less than 1% of all primary laryngeal neoplasms. We report a rare case of laryngeal diffuse large B-cell lymphoma (DLBCL) in an 85-year-old female patient, which was difficult to diagnose even after several biopsies from the primary laryngeal lesion, both under local and general anesthesia, and the diagnosis of DLBCL was obtained from the lymph node biopsy, which appeared in the proximity of the larynx 2 months after the first biopsy from the larynx. Since the diagnosis of laryngeal NHL is sometimes difficult when sufficient samples cannot be obtained, repeated biopsies may be required. Due to the small number of cases, there is no definite consensus regarding the best management of laryngeal NHL. Thus, a standard treatment option for DLBCL, such as 3 courses of R-CHOP (rituximab + cyclophosphamide, doxorubicin, vincristine and prednisone) followed by Involved-field radiation therapy, or 6∼8 course of R-CHOP, are also applied for the treatment of laryngeal DLBCL. For this case, doxorubicin was not adopted and 8 courses of R-COP (rituximab + cyclophosphamide, vincristine and prednisone) at a decreased dose were chosen because of her age (85-year-old) and cardiac hypofunction.     

儿童原发扁桃体弥漫大B细胞淋巴瘤1例并文献复习

目的 探讨儿童原发扁桃体弥漫大B细胞淋巴瘤的临床表现、诊断策略、病理检查及免疫组化特点.方法 回顾2021年1月收治的一例原发扁桃体弥漫大B细胞淋巴瘤的患儿临床资料,通过中国知网CNKI和万方数据库检索国内关于儿童原发扁桃体恶性B细胞淋巴瘤的相关文献,并进行数据分析.结杲患儿,男,10岁4个月,因咽部不适5个月,伴软腭...     

Primary non-Hodgkin's lymphoma of the frontal sinus: case report and review of the literature

Non-Hodgkin's lymphoma of the sinonasal tract is an uncommon lesion, representing 1.5 to 15% of all lymphomas. Most cases of primary non-Hodgkin's lymphoma of the sinonasal tract occur in the maxillary sinus, ethmoid sinus, and nasal cavity; its occurrence in the frontal sinus is extremely rare. We report a case of primary type B non-Hodgkin's lymphoma of the frontal sinus in a 43-year-old man. The patient complained of frontal headaches that had not improved with analgesic drugs, and he presented with a frontal bulge that involved the left upper eyelid; the bulge had progressively enlarged over a 3-month period A biopsy of the mass identified the type B non-Hodgkin's lymphoma. Immunohistochemical study not only confirmed the histologic type of the tumor, it also provided some important information about the primary tumor site. Advances in immunohistochemistry have shown that type B non-Hodgkin's lymphoma is more common in North American and European patients, whereas subtype T is more common in Asians and in some Latin Americans. The treatment of this condition is still controversial, but the combination of radiotherapy and chemotherapy has yielded the best results in all stages of the disease.     

Primary lymphoma of nasolacrimal drainage system: a case report and literature review

Primary lymphoma of the lacrimal drainage system (LDS) is an extremely rare condition. All of those previously reported have been of B-cell origin, with the exception of 1 case report of a natural killer/T-cell lymphoma in a Japanese woman. We report a 41-year-old Chinese woman who had a primary diffuse large B-cell non-Hodgkin lymphoma of left LDS. After 8 cycles of CHOP (cyclophosphamide [Cytoxan], doxorubicin hydrochloride [Adriamycin], vincristine, and prednisone) therapy and further 14 months' follow-up, the patient's conditions were stable without evidence of recurrence. After reviewing associated articles, an interesting finding which, to the best of our knowledge, has never been described before is that all the expired or recurrent cases of primary lymphoma of lacrimal drainage system are of women, including the only 1 case of natural killer/T-cell lymphoma. In our opinion, sex should be considered 1 of the prognostic factors in primary lymphoma of LDS. The relationship between this tumor and hormone response is to be determined.     

84例原发头颈部淋巴瘤临床及病理特征分析

目的 探讨原发头颈部淋巴瘤的临床及病理特征。 方法 回顾性分析84例原发头颈部淋巴瘤患者的病历资料,对其年龄、性别、肿瘤部位、临床表现和病理类型及预后等进行分析。 结果 84例患者中,男性45例(53.6%),女性39例(46.4%),男女比为1.15∶1,年龄19~80岁。病理类型以非霍奇金淋巴瘤为主, 有80例(95.2%),霍奇金淋巴瘤4例(4.8%);非霍奇金淋巴瘤中弥漫大B细胞淋巴瘤39例(48.7%),NK/T淋巴瘤21例(26.3%)。发病部位广泛,依次为:颈部28例(33.3%),鼻腔鼻窦26例(30.9%),扁桃体14例(16.7%),舌根7例(8.3%)。原发于颈部淋巴结及Waldeyer 淋巴环以弥漫大B细胞淋巴瘤为主,原发于鼻腔鼻窦以NK/T细胞淋巴瘤为主。头颈部NK-T细胞淋巴瘤1年生存率为90%, 5年生存率47.6%;头颈部弥漫大B淋巴瘤1年生存率为97.3%,5年生存率58.3%。 结论 原发头颈部淋巴瘤发病率高,临床及影像学无特异性,需及早行组织病理检查,减少漏诊及误诊。     

蝶窦B细胞性非霍奇金淋巴瘤的诊治(附1例报告及文献复习)

目的提高临床医生对蝶窦B细胞性非霍奇金淋巴瘤的认识,概括其诊断要点,避免误诊。方法分析我科收治的1例蝶窦B细胞性非霍奇金淋巴瘤的临床特征、病理特点、诊断要点与治疗,并复习相关文献。结果在全麻下行鼻内镜下蝶窦开放术,并辅以放疗、化疗,随访1年无复发。结论原发于蝶窦的淋巴瘤较罕见,其早期诊断困难。病检取材与CT阅片在其诊断中需要重视。外科手术联合放疗、化疗可以延长早期鼻腔淋巴瘤患者的生存时间、延缓肿瘤的复发。     

Acinic cell carcinoma of maxillary sinus

Acinic cell carcinoma is a tumor that occurs most commonly in the parotid glands. We have experienced a rare case of acinic cell carcinoma of the left maxillary sinus. The patient was a 71-year-old female. She noticed her left nasal congestion and epiphora from left eye in April 1994. She had a history of left maxillary sinus surgery in February, 1972. Antrotomy was performed and histopathological examination of specimen from the maxillary sinus proved acinic cell carcinoma. The tumor was considered to be the recurrence 22 years after initial surgery, because it coincided with the surgical specimen of previous surgery. Radical resection of maxilla was performed for complete resection of tumor with palate reconstruction by left scapula and latissimus dorsi myocutaneus flap. No recurrence is observed for more than 4 years after surgery. Although this tumor is of low grade malignancy, complete resection with adequate surgical margin is advisable due to high incidence of this tumor to recur after long periods of time.     

Primary laryngeal lymphoma: case report

Extranodal laryngeal lymphoma is extremely rare. We report a case of primary laryngeal lymphoma in a 76-year-old man who had presented with a 7-week history of progressive hoarseness. Laryngoscopy revealed asymmetry of the right false vocal fold. Pathology of a deep biopsy specimen identified a malignant, diffuse, CD20-positive, B-cell lymphoma. The stage IE lymphoma completely resolved after treatment with CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) and rituximab. Despite its relative rarity, the consequences of a missed diagnosis warrant vigilance for this type of laryngeal tumor.