On the physiology and biochemistry of the scalp and hair lipids

Analyses were made of the scalp and hair lipids of 67 test persons. These were the most important results: 1. Seborrhoea is caused on one hand by a high secretion performance of the sebaceous glands. A further cause is that a longer period of time passes before a constant lipid amount is established. 2. There was an average of 19.32% of free fatty acids in the scalp and hair lipids on the 1st day after the hair was washed, and 38.68% on the 10th day. These results allow an assessment of the physiological significance of microbial lipolysis outside the secretory ducts of the sebaceous glands. 3. On the hairy head the percentage of free fatty acids in the scalp and hair lipids is independent of the amount of lipids. Such a difference in the concentration of fatty acids as is found between seborrhoea oleosa and seborrhoea sicca on hairless skin can not be found on the hairy head.     

Aging skin and food supplements: the myth and the truth

The frenzied rhythm of our times leads our patients not only to resource to diet integrators—remorselessly overcoming difficulties or prejudices—to fulfill increasingly frequent nutritional needs due to decreasingly “correct” eating habits, but also to fight against a myriad of skin conditions. The rationale of a combined approach for the antiaging treatment of skin is based on the synergic effect between functional substances applied locally, where the problem arises, and other agents working from the inside to correct a need, to restore altered functions or conditions and to guarantee the correct intake of nutrients or active substances. This work discusses the active ingredients mostly used in the oral treatment of skin aging, together with the scientific evidences that do or do not support their use.     

师生恋的伦理透析及应对策略分析

师生恋的背后可能是教师对学生诱骗、性骚扰、性侵的本质。师生恋也往往充斥着非法交易,因此社会各界不乐见师生恋带来的不良影响。国际上基本都禁止师生恋的发生,我国也须加强对师生恋的立法,加强对在校女大学生的保护。     

异常子宫出血与雌孕激素及其受体水平关系的探讨

目的:探讨雌孕激素及其受体水平与子宫异常出血的关系。方法:随机选取门诊异常子宫出血患者,采用化学发光免疫分析仪及试剂盒进行激素水平测定,同时行分段诊刮送病理检查及雌孕激素受体检测。结果:子宫内膜癌、子宫内膜不典型增生、子宫肌瘤、子宫内膜息肉患者E2含量明显高于对照组(P<0.05),子宫肌瘤及有排卵型功血患者P含量与对照组相比差异显著(P<0.05,P<0.01),除有排卵型功血外,其他各种类型子宫异常出血患者的子宫内膜中ER、PR阳性率均明显高于对照组,差异显著(P<0.05,P<0.01及P<0.005)。结论:子宫异常出血与E2、P水平及子宫内膜中ER、PR含量有明显相关性。     

Disorders affecting the skin and the heart

Numerous disorders affect both the skin and the heart. These include inherited and metabolic disorders, rheumatologic diseases, infectious diseases, and a variety of others. In many instances, awareness of this association allows the dermatologist to assist in identifying potentially life-threatening cardiac conditions.     

Tularemia: the disease and the weapon

Tularemia is a bacterial infection usually transmitted via arthropod vectors or direct contact with infected animals. Naturally occurring cases are relatively rare, and can result in six different clinical syndromes. Tularemia is also a potential agent of bioterrorism or biowarfare, and is categorized as a high-level threat. Effective antibiotic treatment is available, including potential use of oral antibiotics in a mass casualty situation. An awareness of potential clinical presentations of tularemia will facilitate timely intervention,appropriate diagnostic testing, and decreased morbidity in the event of a biologic attack with Francisella tularensis.     

Apoptosis, the dermatologist, the venereologist and the patient

Apoptosis is the genetically mediated process whereby individual cells determine their deletion from normal and diseased tissues. Deregulation of apoptosis occurs to a greater or lesser extent in malignant tumours and in certain skin diseases, and also largely accounts for the progressive depletion of CD4⁺ lymphocytes in HIV infection. Greater understanding of apoptosis modulation by oncogenes and tumour suppressor genes such as c-myc. Fas, p53, bcl-2, and abl will facilitate the development of new therapeutic strategies for cancer and other diseases.     

Chronological ageing and photoageing of the fibroblasts and the dermal connective tissue

In recent years, the exposure of human skin to environmental and artificial UV irradiation has increased dramatically. This is due not only to increased solar UV irradiation as a consequence of stratospheric ozone depletion, but also to inappropriate social behaviour with the use of tanning salons still being very popular in the public view. Besides this, leisure activities and a lifestyle that often includes travel to equatorial regions add to the individual annual UV load. In addition to the common long-term detrimental effects such as immunosuppression and skin cancer, the photo-oxidative damage due to energy absorption of UV photons in an oxygenized environment leads to quantitative and qualitative alterations of cells and structural macromolecules of the dermal connective tissue responsible for tensile strength, resilience and stability of the skin. The clinical manifestations of UV/reactive oxygen species (ROS)-induced disturbances result in photoaged skin with wrinkle formation, laxity, leathery appearance as well as fragility, impaired wound healing capacities and higher vulnerability. Strategies to prevent or at least minimize ROS-induced photo-ageing and intrinsic ageing of the skin necessarily include protection against UV irradiation and antioxidant homeostasis.