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1.
Zhiqiang Li Christian Graff Arthur F. Gmitro Scott W. Squire Ali Bilgin Eric K. Outwater Maria I. Altbach 《Magnetic resonance in medicine》2009,61(6):1415-1424
Three‐point Dixon methods have been investigated as a means to generate water and fat images without the effects of field inhomogeneities. Recently, an iterative algorithm (IDEAL, iterative decomposition of water and fat with echo asymmetry and least squares estimation) was combined with a gradient and spin‐echo acquisition strategy (IDEAL‐GRASE) to provide a time‐efficient method for lipid–water imaging with correction for the effects of field inhomogeneities. The method presented in this work combines IDEAL‐GRASE with radial data acquisition. Radial data sampling offers robustness to motion over Cartesian trajectories as well as the possibility of generating high‐resolution T2 maps in addition to the water and fat images. The radial IDEAL‐GRASE technique is demonstrated in phantoms and in vivo for various applications including abdominal, pelvic, and cardiac imaging. Magn Reson Med, 2009. © 2009 Wiley‐Liss, Inc. 相似文献
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3.
目的比较磁共振脂肪抑制FSET2WI、STIRT2WI、IDEALT2WI及CUBEFlexT2WI4种方法显示正常臂丛神经的优劣。资料与方法对14例自愿者行臂丛神经MRI脂肪抑制FSET2WI、STIRT2WI、IDEALT2WI及CUBEFlexT2WI检查。对图像脂肪抑制质量进行肉眼分级评估,并测量信噪比和对比噪声比。结果 IDEALT2WI、CUBEFlexT2WI脂肪抑制质量明显优于FSET2WI(P<0.05),与STIRT2WI相比差异无统计学意义(P>0.05)。信噪比、对比噪声比均值比较各组间差异均有统计学意义(P<0.05),IDEALT2WI>CUBEFlexT2WI>FSET2WI>STIRT2WI。IDEALT2WI和CUBEFlexT2WI图像均可选择不同厚度重建、斜面重建等,从而可显示臂丛神经各段。结论 IDEALT2WI、CUBEFlexT2WI能提供均匀稳定的脂肪抑制,图像信噪比高,可清晰显示臂丛神经。 相似文献
4.
Fast spin-echo triple-echo dixon (fTED) technique for efficient T2-weighted water and fat imaging. 总被引:1,自引:0,他引:1
Jingfei Ma Jong Bum Son Yuxiang Zhou Huong Le-Petross Haesun Choi 《Magnetic resonance in medicine》2007,58(1):103-109
Previously published fast spin-echo (FSE) implementations of a Dixon method for water and fat separation all require multiple scans and thus a relatively long scan time. Further, the minimum echo spacing (esp), a time critical for FSE image quality and scan efficiency, often needs to be increased in order to bring about the required phase shift between the water and fat signals. This work proposes and implements a novel FSE triple-echo Dixon (fTED) technique that can address these limitations. In the new technique, three raw images are acquired in a single FSE scan by replacing each frequency-encoding gradient in a conventional FSE with three consecutive gradients of alternating polarity. The timing of the three gradients is adjusted by selecting an appropriate receiver bandwidth (RBW) so that the water and fat signals for the three corresponding echoes have a relative phase shift of -180 degrees , 0 degrees , and 180 degrees , respectively. A fully automated postprocessing algorithm is then used to generate separate water-only and fat-only images for each slice. The technique was implemented with and without parallel imaging. We demonstrate that the new fTED technique enables both uniform water/fat separation and fast scanning with uncompromised scan parameters, including applications such as T(2)-weighted separate water and fat imaging of the abdomen during breath-holding. 相似文献
5.
Reeder SB Yu H Johnson JW Shimakawa A Brittain JH Pelc NJ Beaulieu CF Gold GE 《Journal of magnetic resonance imaging : JMRI》2006,24(4):825-832
PURPOSE: To compare the iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL) method with fat-saturated T1-weighted (T1W) and T2W fast spin-echo (FSE) and short-TI inversion recovery (STIR) imaging of the brachial plexus and cervical spine. MATERIALS AND METHODS: Images acquired at 1.5T in five volunteers using fat-saturated T1W and T2W FSE imaging and STIR were compared with T1W and T2W IDEAL-FSE images. Examples of T1W and T2W IDEAL-FSE images acquired in patients are also shown. RESULTS: T1W and T2W IDEAL-FSE demonstrated superior fat suppression (P<0.05) and image quality (P<0.05), compared to T1W and T2W fat-saturated FSE, respectively. SNR performance of T1W-IDEAL-FSE was similar to T1W FSE in the spinal cord (P=0.250) and paraspinous muscles (P=0.78), while T2W IDEAL-FSE had superior SNR in muscle (P=0.02) and CSF (P=0.02), and marginally higher cord SNR (P=0.09). Compared to STIR, T2W IDEAL-FSE demonstrated superior image quality (P<0.05), comparable fat suppression (excellent, P=1.0), and higher SNR performance (P<0.001). CONCLUSION: IDEAL-FSE is a promising method for T1W and T2W imaging of the brachial plexus and cervical spine. 相似文献
6.
Multicoil Dixon chemical species separation with an iterative least-squares estimation method. 总被引:1,自引:0,他引:1
Scott B Reeder Zhifei Wen Huanzhou Yu Angel R Pineda Garry E Gold Michael Markl Norbert J Pelc 《Magnetic resonance in medicine》2004,51(1):35-45
This work describes a new approach to multipoint Dixon fat-water separation that is amenable to pulse sequences that require short echo time (TE) increments, such as steady-state free precession (SSFP) and fast spin-echo (FSE) imaging. Using an iterative linear least-squares method that decomposes water and fat images from source images acquired at short TE increments, images with a high signal-to-noise ratio (SNR) and uniform separation of water and fat are obtained. This algorithm extends to multicoil reconstruction with minimal additional complexity. Examples of single- and multicoil fat-water decompositions are shown from source images acquired at both 1.5T and 3.0T. Examples in the knee, ankle, pelvis, abdomen, and heart are shown, using FSE, SSFP, and spoiled gradient-echo (SPGR) pulse sequences. The algorithm was applied to systems with multiple chemical species, and an example of water-fat-silicone separation is shown. An analysis of the noise performance of this method is described, and methods to improve noise performance through multicoil acquisition and field map smoothing are discussed. 相似文献
7.
Two modified fast spin-echo (FSE) techniques (a 2-point and a single-scan triple-echo Dixon) were used for T2-weighted imaging of the head and neck in 7 patients along with conventional FSE with fat saturation. Both Dixon techniques provided consistent and more uniform fat suppression (FS) than conventional FSE. The 2-point Dixon technique was noted to be more susceptible to motion artifacts. The triple-echo Dixon technique offered the best scan time efficiency and overall image quality. 相似文献
8.
Scott B Reeder Brian A Hargreaves Huanzhou Yu Jean H Brittain 《Magnetic resonance in medicine》2005,54(3):586-593
Multipoint water-fat separation methods have received renewed interest because they provide uniform separation of water and fat despite the presence of B0 and B1 field inhomogeneities. Unfortunately, full-resolution reconstruction of partial k-space acquisitions has been incompatible with these methods. Conventional homodyne reconstruction and related algorithms are commonly used to reconstruct partial k-space data sets by exploiting the Hermitian symmetry of k-space in order to maximize the spatial resolution of the image. In doing so, however, all phase information of the image is lost. The phase information of complex source images used in a water-fat separation acquisition is necessary to decompose water from fat. In this work, homodyne imaging is combined with the IDEAL (iterative decomposition of water and fat with echo asymmetry and least squares estimation) method to reconstruct full resolution water and fat images free of blurring. This method is extended to multicoil steady-state free precession and fast spin-echo applications and examples are shown. 相似文献
9.
Ethan K Brodsky James H Holmes Huanzhou Yu Scott B Reeder 《Magnetic resonance in medicine》2008,59(5):1151-1164
Chemical-shift artifacts associated with non-Cartesian imaging are more complex to model and less clinically acceptable than the bulk fat shift that occurs with conventional spin-warp Cartesian imaging. A novel k-space based iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL) approach is introduced that decomposes multiple species while simultaneously correcting distortion of off-resonant species. The new signal model accounts for the additional phase accumulated by off-resonant spins at each point in the k-space acquisition trajectory. This phase can then be corrected by adjusting the decomposition matrix for each k-space point during the final IDEAL processing step with little increase in reconstruction time. The technique is demonstrated with water-fat decomposition using projection reconstruction (PR)/radial, spiral, and Cartesian spin-warp imaging of phantoms and human subjects, in each case achieving substantial correction of chemical-shift artifacts. Simulations of the point-spread-function (PSF) for off-resonant spins are examined to show the nature of the chemical-shift distortion for each acquisition. Also introduced is an approach to improve the signal model for species which have multiple resonant peaks. Many chemical species, including fat, have multiple resonant peaks, although such species are often approximated as a single peak. The improved multipeak decomposition is demonstrated with water-fat imaging, showing a substantial improvement in water-fat separation. 相似文献
10.
W. Umek A. Ba-Ssalamah R. Prokesch R. Mallek K. Heimberger K. Hittmair 《European radiology》1998,8(3):409-415
The aim of our study was to compare gradient-spin-echo (GRASE) to fast-spin-echo (FSE) sequences for fast T2-weighted MR
imaging of the brain. Thirty-one patients with high-signal-intensity lesions on T2-weighted images were examined on a 1.5-T
MR system. The FSE and GRASE sequences with identical sequence parameters were obtained and compared side by side. Image assessment
criteria included lesion conspicuity, contrast between different types of normal tissue, and image artifacts. In addition,
signal-to-noise, contrast-to-noise, and contrast ratios and were determined. The FSE technique demonstrated more lesions than
GRASE and with generally better conspicuity. Smaller lesions in particular were better demonstrated on FSE because of lower
image noise and slightly weaker image artifacts. Gray–white differentiation was better on FSE. Ferritin and hemosiderin depositions
appeared darker on GRASE, which resulted in better contrast. Fatty tissue was less bright on GRASE. With current standard
hardware equipment, the FSE technique seems preferable to GRASE for fast T2-weighted routine MR imaging of the brain. For
the assessment of hemosiderin or ferritin depositions, GRASE might be considered.
Received 14 April 1997; Accepted 8 August 1997 相似文献
11.
Scott B. Reeder Angel R. Pineda Zhifei Wen Ann Shimakawa Huanzhou Yu Jean H. Brittain Garry E. Gold Christopher H. Beaulieu Norbert J. Pelc 《Magnetic resonance in medicine》2005,54(3):636-644
Chemical shift based methods are often used to achieve uniform water–fat separation that is insensitive to Bo inhomogeneities. Many spin‐echo (SE) or fast SE (FSE) approaches acquire three echoes shifted symmetrically about the SE, creating time‐dependent phase shifts caused by water–fat chemical shift. This work demonstrates that symmetrically acquired echoes cause artifacts that degrade image quality. According to theory, the noise performance of any water–fat separation method is dependent on the proportion of water and fat within a voxel, and the position of echoes relative to the SE. To address this problem, we propose a method termed “iterative decomposition of water and fat with echo asymmetric and least‐squares estimation” (IDEAL). This technique combines asymmetrically acquired echoes with an iterative least‐squares decomposition algorithm to maximize noise performance. Theoretical calculations predict that the optimal echo combination occurs when the relative phase of the echoes is separated by 2π/3, with the middle echo centered at π/2+πk (k = any integer), i.e., (–π/6+πk, π/2+πk, 7π/6+πk). Only with these echo combinations can noise performance reach the maximum possible and be independent of the proportion of water and fat. Close agreement between theoretical and experimental results obtained from an oil–water phantom was observed, demonstrating that the iterative least‐squares decomposition method is an efficient estimator. Magn Reson Med, 2005. © 2005 Wiley‐Liss, Inc. 相似文献
12.
Ananth J. Madhuranthakam PhD Huanzhou Yu PhD Ann Shimakawa MS Reed F. Busse PhD Martin P. Smith MD Scott B. Reeder MD PhD Neil M. Rofsky MD Jean H. Brittain PhD Charles A. McKenzie PhD 《Journal of magnetic resonance imaging : JMRI》2010,32(3):745-751
Purpose:
To develop a robust 3D fast spin echo (FSE) T2‐weighted imaging method with uniform water and fat separation in a single acquisition, amenable to high‐quality multiplanar reformations.Materials and Methods:
The Iterative Decomposition of water and fat with Echo Asymmetry and Least squares estimation (IDEAL) method was integrated with modulated refocusing flip angle 3D‐FSE. Echoes required for IDEAL processing were acquired by shifting the readout gradient with respect to the Carr‐Purcell‐Meiboom‐Gill echo. To reduce the scan time, an alternative data acquisition using two gradient echoes per repetition was implemented. Using the latter approach, a total of four gradient echoes were acquired in two repetitions and used in the modified IDEAL reconstruction.Results:
3D‐FSE T2‐weighted images with uniform water–fat separation were successfully acquired in various anatomies including breast, abdomen, knee, and ankle in clinically feasible scan times, ranging from 5:30–8:30 minutes. Using water‐only and fat‐only images, in‐phase and out‐of‐phase images were reconstructed.Conclusion:
3D‐FSE‐IDEAL provides volumetric T2‐weighted images with uniform water and fat separation in a single acquisition. High‐resolution images with multiple contrasts can be reformatted to any orientation from a single acquisition. This could potentially replace 2D‐FSE acquisitions with and without fat suppression and in multiple planes, thus improving overall imaging efficiency. J. Magn. Reson. Imaging 2010;32:745–751. © 2010 Wiley‐Liss, Inc. 相似文献13.
Reeder SB Markl M Yu H Hellinger JC Herfkens RJ Pelc NJ 《Journal of magnetic resonance imaging : JMRI》2005,22(1):44-52
PURPOSE: To decompose multicoil CINE steady-state free precession (SSFP) cardiac images acquired at short echo time (TE) increments into separate water and fat images, using an iterative least-squares "Dixon" (IDEAL) method. MATERIALS AND METHODS: Multicoil CINE IDEAL-SSFP cardiac imaging was performed in three volunteers and 15 patients at 1.5 T. RESULTS: Measurements of signal-to-noise ratio (SNR) matched theoretical expectations and were used to optimize acquisition parameters. TE increments of 0.9-1.0 msec permitted the use of repetition times (TRs) of 5 msec or less, and provided good SNR performance of the water-fat decomposition, while maintaining good image quality with a minimum of banding artifacts. Images from all studies were evaluated for fat separation and image quality by two experienced radiologists. Uniform fat separation and diagnostic image quality was achieved in all images from all studies. Examples from volunteers and patients are shown. CONCLUSION: Multicoil IDEAL-SSFP imaging can produce high quality CINE cardiac images with uniform water-fat separation, insensitive to Bo inhomogeneities. This approach provides a new method for reliable fat-suppression in cardiac imaging. 相似文献
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目的 比较IDEAL T2WI、FSE T2WI序列在脊柱脂肪抑制扫描中的应用价值.资料与方法 35例脊柱MRI检查患者(颈椎10例、胸椎8例、腰椎17例)同时采用IDEAL T2WI、FSE T2WI两种脂肪抑制序列扫描,对图像脂肪抑制质量进行主观评价分级评估并测量信噪比.结果 FSE T2WI脂肪抑制质量主观评价分级为颈椎( 1.30±0.48)级、胸椎(1.80±0.71)级、腰椎(2.30±0.69)级,而IDEAL T2WI序列颈、胸椎均为(3.00±0.00)级、腰椎为(2.80±0.56)级;FSE T2WI脂肪抑制序列信噪比平均值分别为颈( 8.73±4.66)、胸(11.33±9.27)、腰(6.81±10.15),IDEAL T2WI序列信噪比平均值分别为颈( 18.90±7.71)、胸(26.02±11.61)、腰(19.57±9.12),两序列信噪比差异有统计学意义(t=3.73、5.72、11.23,P<0.05).结论 脊柱MRI脂肪抑制扫描IDEAL T2WI序列优于FSE T2WI序列,IDEAL T2WI序列能提供更均匀稳定的脂肪抑制效果,脊柱图像信噪比高,可清晰显示脊柱病变. 相似文献
15.
Purpose
The aim of this work is to prospectively compare the effectiveness of iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL), T2-weighted fast spin-echo (FSE), and spoiled gradient-echo (SPGR) MR imaging to frequency selective fat suppression (FSFS) protocols for minimizing metallic artifacts in postoperative ankles with metallic hardware.Materials and methods
The T2-weighted and SPGR imaging with IDEAL and FSFS were performed on 21 ankles of 21 patients with metallic hardware. Two musculoskeletal radiologists independently analyzed techniques for visualization of ankle ligaments and articular cartilage, uniformity of fat saturation, and relative size of the metallic artifacts. A paired t test was used for statistical comparisons of MR images between IDEAL and FSFS groups.Results
IDEAL T2-weighted FSE and SPGR images enabled significantly improved visualization of articular cartilage (p?<?0.05), the size of metallic artifact (p?<?0.05), and the uniformity of fat saturation (p?<?0.05). However, no significant improvement was found in the visibility of ligaments.Conclusions
IDEAL T2-weighted FSE and SPGR imaging effectively reduces the degree of tissue-obscuring artifacts produced by fixation hardware in ankle joints and improves image quality compared to FSFS T2-weighted FSE and SPGR imaging. However, visibility of ligaments was not improved using IDEAL imaging.16.
OBJECTIVE: The objective of this article is to discuss the acquisition of high-quality MR images of the musculoskeletal system with uniform fat suppression using iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL). IDEAL is a three-point water-fat separation method that provides robust fat suppression even in the complex magnetic environments commonly encountered during clinical musculoskeletal imaging. CONCLUSION: The IDEAL technique provides uniform fat saturation even in complex magnetic environments and simultaneously produces in-phase and opposed-phase images that may be useful for characterization of osseous lesions. The IDEAL water-fat separation method is highly versatile and has been successfully combined with T1-weighted, T2-weighted, steady-state free precession, and spoiled gradient-recalled echo techniques to produce high-quality MR images in clinically acceptable scanning times. 相似文献
17.
Christina A. Chen BA Richard Kijowski MD Lauren M. Shapiro BA Michael J. Tuite MD Kirkland W. Davis MD Jessica L. Klaers PhD Walter F. Block PhD Scott B. Reeder MD PhD Garry E. Gold MD 《Journal of magnetic resonance imaging : JMRI》2010,32(1):173-183
Purpose:
To compare six new three‐dimensional (3D) magnetic resonance (MR) methods for evaluating knee cartilage at 3.0T.Materials and Methods:
We compared: fast‐spin‐echo cube (FSE‐Cube), vastly undersampled isotropic projection reconstruction balanced steady‐state free precession (VIPR‐bSSFP), iterative decomposition of water and fat with echo asymmetry and least‐squares estimation combined with spoiled gradient echo (IDEAL‐SPGR) and gradient echo (IDEAL‐GRASS), multiecho in steady‐state acquisition (MENSA), and coherent oscillatory state acquisition for manipulation of image contrast (COSMIC). Five‐minute sequences were performed twice on 10 healthy volunteers and once on five osteoarthritis (OA) patients. Signal‐to‐noise ratio (SNR) and contrast‐to‐noise ratio (CNR) were measured from the volunteers. Images of the five volunteers and the five OA patients were ranked on tissue contrast, articular surface clarity, reformat quality, and lesion conspicuity. FSE‐Cube and VIPR‐bSSFP were compared to IDEAL‐SPGR for cartilage volume measurements.Results:
FSE‐Cube had top rankings for lesion conspicuity, overall SNR, and CNR (P < 0.02). VIPR‐bSSFP had top rankings in tissue contrast and articular surface clarity. VIPR and FSE‐Cube tied for best in reformatting ability. FSE‐Cube and VIPR‐bSSFP compared favorably to IDEAL‐SPGR in accuracy and precision of cartilage volume measurements.Conclusion:
FSE‐Cube and VIPR‐bSSFP produce high image quality with accurate volume measurement of knee cartilage. J. Magn. Reson. Imaging 2010;32:173–183. © 2010 Wiley‐Liss, Inc. 相似文献18.
Gradient- and spin-echo T2-weighted imaging for SPIO-enhanced detection and characterization of focal liver lesions 总被引:2,自引:0,他引:2
Yoshikawa T Mitchell DG Hirota S Ohno Y Oda K Maeda T Fujii M Sugimura K 《Journal of magnetic resonance imaging : JMRI》2006,23(5):712-719
PURPOSE: To evaluate superparamagnetic iron oxide (SPIO)-enhanced breathhold T2-weighted GRASE imaging in detection and characterization of focal liver lesions. MATERIALS AND METHODS: In 30 patients (including 20 with cirrhosis) with 39 malignant and 25 benign lesions, gradient- and spin-echo (GRASE) images with two echo times (75 and 90 msec; GRASE75 and GRASE90) were obtained prior to and following administration of SPIO, and compared with respiratory-triggered and breathhold fast spin-echo (RT-FSE and BH-FSE) images. Two readers evaluated image quality and reviewed 240 liver segments for sensitivity and specificity. Signal-to-noise ratio (SNR), and its reduction in liver and spleen after administration of SPIO, and lesion-to-liver contrast-to-noise ratio (CNR) were measured. RESULTS: Compared with RT-FSE and BH-FSE, GRASE reduced scan time by 77% to 82% and 21% to 27%, respectively. The image qualities with BH-FSE and GRASE75 were higher than with BH-FSE and GRASE90. BH-FSE showed higher specificity than RT-FSE and GRASE90, but otherwise there were no significant differences between pulse sequences for sensitivity or specificity. The mean SNR and CNR of the lesions with RT-FSE were significantly higher than with the other methods. SPIO-induced signal reduction of liver SNR was smallest with BH-FSE. CONCLUSION: GRASE is faster and more sensitive to SPIO than FSE, but its sensitivity and specificity were slightly inferior to those of BH-FSE. Image quality is a current limitation. 相似文献
19.
The application of T2*-weighted gradient and spin-echo (GRASE) imaging was investigated as a method for blood oxygenation level-dependent (BOLD)-based functional magnetic resonance imaging (fMRI). The displaced-echo method was implemented to produce single-shot T2*-weighted GRASE images. This technique removes the requirement that the Carr-Purcell Meiboom-Gill (CPMG) condition be fulfilled. T2*-weighted GRASE images that are free from interference artifacts can thus be obtained, hence allowing the possibility of using single-shot GRASE for BOLD-based functional imaging. The method was demonstrated at 3 T and gave robust and reproducible activation-induced signal changes. 相似文献
20.
The aim of this study was to evaluate the sensitivity of gradient-and-spin-echo (GRASE) sequences to susceptibility effects.
GRASE sequences with 21 and 33 echoes per echo train were compared with a T2-weighted FSE sequence with an echo train length
of 5 by means of MRI in phantoms, volunteers (n = 10), and patients (n = 19) with old hemorrhagic brain lesions. All experiments were performed on a 1.0-T clinical MR system (Impact Expert, Siemens
AG, Erlangen, Germany) with constant imaging parameters. Contrast-to-noise ratios (CNRs) of tubes doped with iron oxides at
different concentrations, of brain areas with physiological iron deposition (red nucleus, substantia nigra), and of areas
of old brain hemorrhage were calculated for FSE and GRASE pulse sequences. Areas of old brain hemorrhage were also qualitatively
analyzed for the degree of visible susceptibility effects by blinded reading. The CNR of iron oxide tubes and iron-containing
brain areas decreased with increasing echo trains of GRASE sequences. The CNR of GRASE sequences decreased when compared with
CNR of their FSE counterparts (GRASE 21 echo trains 23.8 ± 0.8, FSE 5 echo trains 26.7 ± 0.9; p≤ 0.01). Qualitative analysis confirmed these measurements. FSE with an ETL of 5 demonstrated significantly stronger susceptibility
effects than their GRASE counterpart with an ETL of 21. The results demonstrate that GRASE sequences do not necessarily compensate
for the reduced sensitivity of FSE to susceptibility effects. The complex signal behavior of GRASE makes conventional SE,
gradient echo, or FSE sequences containing shorter echo trains preferable when patients with intracranial hemorrhage are clinically
evaluated.
Received 12 November 1997; Revision received 18 April 1997; Accepted 1 September 1997 相似文献