针刺对轻中度原发性高血压患者血压变异性的影响

目的:通过应用动态血压监测(ABPM)观察针刺对轻中度原发性高血压患者血压变异性(BPV)的影响。方法:以人迎穴为主穴进行针刺,观察患者治疗前后24 h、日间、夜间平均血压水平及日间、夜间血压负荷、血压变异性。结果:患者治疗前后24 h、日间、夜间平均血压水平及日间、夜间血压负荷、血压变异性都呈下降趋势。结论:针刺治疗可以降低高血压患者的日间及夜间血压负荷值,能够平稳降压,减少血压波动,有助于保护靶器官。     

醒脑开窍针刺法治疗高血压合并中风临床观察

目的观察醒脑开窍针刺法对高血压合并中风病的降压效果。方法将150例高血压病合并中风的患者纳入研究病例,在醒脑开窍针剌法的基础上,配合人迎、曲池、合谷、太冲、足三里穴。于治疗前后分别对患者进行24h动态血压监测,观察24h、日间、夜间的平均收缩压和平均舒张压,脉压以及血压昼夜节律的变化。结果24h、日间、夜间的平均收缩压和平均舒张压,脉压与治疗前比较均有显著性降低（P〈0．05）,针刺可以使64．7％患者恢复正常杓型节律。结论醒脑开窍针刺法能有效地降低高血压合并中风病人的血压水平,纠正患者的血压节律。     

针刺人迎穴为主治疗原发性高血压病临床疗效Meta分析

目的:通过Meta分析定量系统评价针刺人迎穴为主治疗原发性高血压病的疗效与安全性。方法:通过计算机逐一检索相关医学文献数据库,包括中国生物医学文献数据(CBM)、中国知网(CNKI)、维普科技期刊数据库(VIP)、万方科技信息数据库、中国医院知识总库(CHKD),英文库包括Pubmed、Cochrane Library、Embase、Web of science。筛选纳入自建库至2016年1月有关针刺人迎穴为主治疗原发性高血压病的随机对照试验(RCT),并追溯相关参考文献。由2名评价者独立筛选评估后,采用Rev Man 5.3软件进行Meta分析。结果:最终纳入8个研究,共588例受试者。Meta分析显示:针刺人迎穴单穴或组方具有协同西药降压疗效,且优于西药单用,差异有统计学意义,总有效率[RR=1.26,95%CI(1.13,1.41),P0.000 1]、疗程后收缩压指标[MD=-9.98,95%CI(-15.87,-4.08),P=0.000 9]、疗程后舒张压指标[MD=-6.06,95%CI(-9.61,-2.51),P=0.000 8]及针刺即刻降压效应指标和疗程后随访长期降压效应指标等。结论:针刺人迎穴单穴或组方具有协同西药降压疗效,且优于单纯西药治疗;上述论点尚需多中心、大样本的高品质随机双盲对照试验的进一步证实。     

羚羊角胶囊对老年单纯收缩期高血压患者血压变异性、脉压及左心室质量的影响

目的:观察羚羊角胶囊对老年单纯收缩期高血压患者血压变异性、脉压和左心室质量的影响。方法:选择78例单纯收缩期老年高血压患者,在服用苯那普利基础上服用羚羊角胶囊4个月,比较治疗前、后24h收缩压、舒张压、脉压、左心室质量的变化。结果:服羚羊角胶囊4个月后24h及日间收缩压变异性、舒张压变异性、夜间收缩压变异性、24h及日间平均压变异性明显降低(P0.05)、脉压缩小(P0.05)、左心室质量在加服羚羊角胶囊后明显下降(P0.05),24h收缩压和舒张压有下降趋势但差异无显著性。结论:在常规西药治疗基础上加用羚羊角胶囊更有助于平稳、持续安全降压,缩小脉压,更好保护靶器官。     

针刺人迎穴为主对原发性高血压降压效应观察

目的:观察针刺对高血压病血压的即刻作用及长期影响.方法:原发性高血压患者70例,于每日14:00-16:00针刺人迎、合谷、太冲、曲池、足三里,记录患者每日针刺前以及针刺5 min、15 min、30min的血压值,每周治疗5天休息2天,共治疗3个月.比较同一天内针刺各时点与针刺前血压,比较每隔15天针刺前与第1天的针刺前血压.结果:同一天针刺各时点收缩压较针刺前收缩压下降显著,差异具有统计学意义(均P＜0.05),第1天、第15天、第30天及第60天各时点舒张压较针刺前下降,差异有统计学意叉(均P＜0.05);治疗3个月期间,每隔15天针刺前的收缩压及舒张压与第1天针刺前比较均下降明显(均P＜0.05).结论:针刺治疗原发性高血压既可降低即刻血压,又可维持降压效应,起到长期平稳降压的作用.     

人迎穴干预原发性高血压病的研究进展

目的检索近年来有关人迎穴治疗原发性高血压病的文献,分析了解其临床与实验研究进展情况。方法通过计算机逐一检索相关医学文献数据库,包括中国生物医学文献数据(CBM)、中国知网(CNKI)、维普科技期刊数据库(VIP)、万方科技信息数据库、中国医院知识总库(CHKD),英文库包括Pubmed、Cochrane Library、Embase、Web of science。筛选纳入自建库至2016年1月有关针刺人迎穴治疗原发性高血压病的相关文献进行描述性分析。结果在临床研究进展方面,分析人迎穴组方针刺降压、人迎穴单穴针刺降压及人迎穴非针刺降压的疗效,以及相关实验研究进展。结论明确目前研究之优势与不足,为今后更深入的临床、实验研究指明方向。     

推桥弓穴对原发性高血压的即时降压效应观察

目的：观察推桥弓穴降压的即时效应。方法：治疗组35例采用推桥弓穴治疗,对照组采用安慰性推拿治疗。治疗1次后分别在即刻、10min、30min时观察两组收缩压、舒张压、平均血压及心率的变化情况。结果：治疗组降压的即时效应明显,而对照组无明显降压效果。结论：推桥弓穴对原发性高血压即时降压效果明显,其中降低收缩压和平均血压较明显,而降低舒张压效果不明显,心率也无明显变化。降低收缩压和平均血压的效应在30min后逐渐减弱。     

针刺对老年脑梗死伴原发性高血压患者血压变异性的影响

目的:观察针刺对老年脑梗死伴发原发性高血压患者血压变异性(BPV)的影响。方法:76例老年脑梗死伴原发性高血压患者随机分为观察组和对照组,每组38例。对照组给予"醒脑开窍"针刺法及口服硝苯地平控释片(拜新同)治疗,观察组在对照组治疗基础上行"活血散风、调和肝脾"针刺法,穴取人迎、合谷、曲池、足三里、太冲,留针30 min。每天1次,每周5次,共治疗8周(40次)。监测两组患者24 h动态血压,观察治疗前、治疗8周后血压及血压变异性的变化,并记录治疗过程中不良反应发生情况。结果:两组患者治疗8周后24 h平均收缩压(SBP)、舒张压(DBP),白昼SBP、DBP,夜间SBP、DBP均较治疗前降低(P0.05),且观察组低于对照组(P0.05)。治疗8周后观察组白天、夜间及24h的收缩压变异性(SBPV)、舒张压变异性(DBPV)均较治疗前降低(P0.05),而对照组治疗前后比较差异均无统计学意义(P0.05)。结论:"活血散风、调和肝脾"配穴针刺法对改善老年脑梗死伴原发性高血压患者的血压及血压变异性效果明显。     

针刺太冲穴、人迎穴对自发性高血压大鼠降压效果比较

目的:探讨针刺太冲穴、人迎穴对自发性高血压(SHR)大鼠降压效果的差异。方法:6只Wistar大鼠为对照组,24只SHR大鼠随机分为模型组、太冲组、人迎组和非穴组,每组6只。每天固定时间针刺治疗1次,共14d。采用无创尾动脉血压测量技术检测血压。结果:与对照组比较,模型组大鼠同期收缩压(SBP)、舒张压(DBP)、平均动脉压(MAP)显著增高(P<0.05),太冲组SHR大鼠SBP自第7天开始显著下调(P<0.05),人迎组SHR大鼠自第6天开始显著下调(P<0.05);太冲组和人迎组SHR大鼠DBP和MAP自第6天开始显著下调(P<0.05),降压效果呈时间依赖性。结论:针刺太冲、人迎穴可显著降低SHR大鼠血压,但太冲穴和人迎穴降压效果差异无统计学意义。     

不同参数针刺治疗原发性高血压的正交优化方案研究

目的:分析不同选穴、留针时间、针刺深度对原发性高血压患者24 h血压负荷及昼夜节律的影响,优选最佳针刺降压方案。方法:纳入48例临床病例,采用正交试验设计,按照3因素2水平,即选穴(人迎、太冲)、留针时间(15、30 min)、针刺深度(浅刺、深刺),分为8组,每组6例,观察针刺前后24 h动态血压负荷及血压昼夜节律的变化。结果:(1)针刺深度对收缩压负荷的影响最为显著(P<0.05),各因素不同水平的影响程度为:人迎>太冲,15 min<30 min,浅刺<深刺,最佳调节收缩压方案为深刺人迎30 min;(2)留针时间对舒张压负荷的影响最为显著(P<0.05),各因素不同水平的影响程度为:人迎<太冲,15 min<30 min,浅刺<深刺,最佳调节舒张压方案为深刺太冲30 min;(3)不同因素对于昼夜节律的影响程度为针刺深度>留针时间>选穴;各因素不同水平对昼夜节律的影响程度为:人迎<太冲,15 min<30 min,浅刺<深刺。最佳调节昼夜节律的方案为深刺太冲30 min。结论:深刺人迎或太冲30 min为针刺调节收缩压负荷、舒张压负荷及血压昼夜节律的最佳方案。     

CLINICAL OBSERVATION ON ACUPUNCTURE IN TREATING ESSENTIAL HYPERTENSION WITH TARGET-ORGAN DAMAGE

Objective: To compare the effects of acupuncture on essential hypertension with and without target-organ damage.Methods: Sixty-six patients with essential hypertension were treated, 36 patients with target-organ damage as the treatment group, and 30 patients without target-organ damage as the control group.All subjects were given the treatment of acupuncture primarily for 4 weeks.In the process of acupuncture treatment, two groups received immediate blood pressure measurement respectively, and 24-hour ambulatory blood pressure monitoring before and after acupuncture treatment.We compared the decreasing-dosage rate and effectiveness between the two groups, the immediate blood pressure, 24-hour ambulatory blood pressure, daytime blood pressure, night blood pressure before and after treatment, and blood pressure variation between daytime and nighttime.Results: 1.The decreasing-dosage rate of the treatment groupis lower than that of the control group, meanwhile, the effective rate of the treatment group is also lower than that of the control group.2.After the acupuncture, patients in both groups have a significant decline in systolic pressure, diastolic pressure, 24-hour average systolic pressure and diastolic pressure, daytime systolic pressure and diastolic pressure, nightly systolic pressure and diastolic pressure.Because of the acupuncture therapy, the variation of the two groups in daytime systolic pressure, diastolic pressure and nocturnal diastolic blood pressure is lower obviously than that of before the treatment.3.After acupuncture for 28 d, the treatment group's immediate systolic blood pressure and diastolic blood pressure were higher than those in the control group, and so did the 24-hour ambulatory systolic pressure, diastolic pressure, daytime systolic pressure, diastolic pressure and mean night systolic pressure after acupuncture treatment.Conclusion: The effect of acupuncture on hypertension is obvious.It shows better effect in primary hypertension with unincorporated merger target-organ damage than in primary hypertension with target-organ damage.     

CURATIVE EFFECT OBSERVATION OF ACUPUNCTURE IN TREATING FORTY CASES OF PRIMARY HYPERTENSION DISEASE

Objective: To observe the influence of acupuncture on immediate blood pressure, blood pressure at 8:00, 16:00 o'clock and 24-hour dynamic blood pressure of 40 patients with primary hypertension disease.Methods: Needles were inserted in bilateral Renying(ST9), Hegu(LI4), Taichong(LR3), Quchi(LI11), and Zusanli(ST36) at daily time of 9:00 and 15:00, and patients' immediate blood pressure value 20 min after insertion, blood pressure value at daily 8:00, 16:00, and 24-hour dynamic blood pressure were recorded, 30 d for one period of treatment, 2 d off per week.Immediate blood pressure values, 8:00 and 16:00 blood pressure values and two dynamic blood pressure values at 3 d before treatment and the last 3 d of treatment were compared.Results: The immediate blood pressure value, 8:00 and 16:00 blood pressure value and dynamic blood pressure value significantly decreased as compared with before treatment, especially the systolic blood pressure, and there was statistically significant difference(P0.05).Conclusion: Acupuncture could reduce the immediate blood pressure value, mean value of day and night blood pressure, blood pressure load, blood pressure variability and morning blood pressure, effectively improve the rhythm of day and night blood pressure, and reverse the non-scoop type blood pressure.     

CLINICAL OBSERVATION ON ACUPUNCTURE TREATMENT OF MILD TO MODERATE HYPERTENSION

Objective: To determine the effects of acupuncturing point Renying(ST9) at different frequencies on mild to moderate hypertension.Methods: From July 2012 to June 2013, the hypertension clinic at the First Teaching Hospital of Tianjin University of Traditional Chinese Medicine completed treatment on 38 patients(20 cases in Renying high-frequency group(RHFG), and 18 cases in Renying low-frequency group(RLFG)), using 24-hour ambulatory blood pressure indicators to investigate the effects of different needle manipulations on blood pressure.Results: Compared with before treatment, nighttime blood pressure of the RHFG was significantly lower after 6 and 12 weeks of treatment(P0.05); da ytime and nighttime blood pressure of the RLTG was lower after 6 weeks of treatment, but tended to rebound after 12 weeks of treatment.Conclusion: Renying high-frequency acupuncture has a lasting effect in lowering nighttime blood pressure; whereas Renying low-frequency acupuncture tends to lower both daytime and nighttime blood pressure, but is prone to develop tolerance.     

捻转补法针刺人迎穴干预原发性高血压亚急症的效应观察

目的观察不同手法针刺人迎穴对高血压亚急症患者血压的影响。方法将60例高血压亚急症患者随机分为观察组（捻转补法针刺人迎穴）、对照组（无手法针刺人迎穴），比较治疗前、治疗后3至360min期间的血压变化。结果与对照组比较观察组具有降压效果迅捷、稳定、持续时间长等特点。结论捻转补法针剌人迎穴可起到治疗原发性高血压亚急症的较佳效应。     

GENERAL SITUATION OF THE ANTIHYPERTENSIVE EFFECT OF ACUPUNCTURING RENYING POINT

This article introduces needling Renying as the main acupoint to treat hypertension.The author expounded that needling Renying can effectively control hypertension from the following four aspects: decreasing the blood pressure instantly, controlling the morning blood pressure, co-effect of acupuncture combined with blood pressure reduction drugs and the long-term therapeutic effect The author also pointed out that several aspects still needs to be improved, including paying attention to the improvement of diastolic blood pressure, completion of experiment data, avocations of reducing of drugs combined with acupuncture and intensive study on mechanism.     

针刺人迎穴的降压作用研究概况

人迎穴被医务工作者应用于治疗心脑血管、内分泌系统、神经系统等疾病。从天津中医药大学第一附属医院以人迎穴为主穴的方法治疗高血压病的临床相关研究，以及人迎穴的降压机理研究等方面考证相关文献，并证明其对于高血压病的治疗确实起到了良好的作用与效果。