两种血管闭合器在经股动脉途径冠状动脉介入治疗中的疗效比较

目的比较Angio-Seal血管闭合器和Starclose闭合器在经股动脉途径冠状动脉介入治疗中封堵穿刺点的即刻成功率、术后24小时及术后1周与穿刺有关并发症。方法选取2008年1月至2010年12月经股动脉途径介入治疗的冠心病患者277例,其中135例予Angio-Seal血管闭合器封堵穿刺点,142例予Starclose血管闭合器封堵穿刺点,比较二者术后即刻封堵成功率、术后24小时及1周内穿刺点出血、血肿、假性动脉瘤、局部皮肤破溃感染、动脉夹层、迷走反射等与穿刺有关并发症。结果两组患者术后即刻手术成功率、止血时间及制动时间差异无统计学意义（P〉0.05）,术后24小时Starclose组与穿刺有关并发症6例,Angio-Seal组14例（P〈0.05）。术后1周Starclose组与穿刺有关并发症8例,Angio-Seal组18例（P〈0.05）。结论 Starclose血管闭合器封堵股动脉穿刺点较Angio-Seal闭合器更安全可靠,值得在临床应用推广。     

冠状动脉造影术后应用血管封堵器的疗效及护理

目的探讨采用Angio-Seal经皮血管封堵器行冠状动脉造影术后股动脉穿刺点止血的疗效及术后护理。方法215例采用Angio-Seal经皮血管封堵器行冠状动脉造影术后股动脉穿刺点止血患者及同期217例行常规压迫止血患者的术后护理及术后并发症进行比较。结果采用Angio-Seal经皮血管封堵器术后康复时间短、并发症少。结论Angio-Seal经皮血管封管器安全、可靠,明显缩短止血时间及制动时间,无明显的穿刺部位血管并发症。     

冠状动脉造影术后应用血管封堵器的疗效及护理

目的 探讨采用Angio-Seal经皮血管封堵器行冠状动脉造影术后股动脉穿刺点止血的疗效及术后护理.方法 215例采用Angio-Seal经皮血管封堵器行冠状动脉造影术后股动脉穿刺点止血患者及同期217例行常规压迫止血患者的术后护理及术后并发症进行比较.结果 采用Angio-Seal经皮血管封堵器术后康复时间短、并发症少.结论 Angio-Seal经皮血管封管器安全、可靠,明显缩短止血时间及制动时间,无明显的穿刺部位血管并发症.     

冠心病介入诊疗术应用Angio-Seal血管闭合器的护理进展

从Angio-Seal血管闭合器的结构特点、临床护理研究、术前护理、术后护理、健康指导等方面对冠心病介入诊疗术应用Angio-Seal血管闭合器的护理进展进行综述.     

冠心病介入诊疗术应用Angio-Seal血管闭合器的护理进展

从Angio-Seal血管闭合器的结构特点、临床护理研究、术前护理、术后护理、健康指导等方面对冠心病介入诊疗术应用Angio-Seal血管闭合器的护理进展进行综述。     

Angio-Seal与Perclose血管封堵器止血效果的比较

背景:冠状动脉内支架放置后需要强化抗凝及抗血小板治疗,使得止血问题越来越受到重视.随着动脉穿刺闭合器数量和种类的增加,能否减少并发症存在着较大争议.目的:评估冠状动脉造影与经皮冠状动脉腔内成形及支架置入后应用Angio-Seal与Percloser两种血管封堵器封闭股动脉穿刺点的疗效及安全性.设计、时间及地点:同期非随机对比观察实验,2003-01/2007-11东南大学附属中大医院心内科.对象:对接受冠状动脉造影及经皮冠状动脉腔内成形及支架置入治疗(FTCA/stent)的56例患者分为Angio-Scal组22例(冠状动脉造影患者10例,PTCA/stent患者12例)和Percloser组34例(冠状动脉造影患者20例,PTCA/stent患者14例).方法:完成冠状动脉造影与经皮冠状动脉腔内成形及支架置入治疗后立即予穿刺侧股动脉造影.若穿刺点在股总动脉,距离分叉4mm以上以Angio-Seal和Percloser血管封堵器封闭穿刺点,术后患肢制动3h.主要观察指标:两组止血时间、卧床及制动时间、并发症的发生情况.结果:①Angio-Seal组平均止血时间为(4.0±2.5)min, Perclose组平均止血时间为(8.0±4.5)min,两组比较差异有显著性意义(P<0.01).②两组平均操作时间和平均卧床制动时间比较差异无显著性意义(P>0.05).③两组共有3例缝合失败,其中Angio-Seal组1例,Percloscr组2例,改为压迫止血.Perclose组2例出现血管迷走神经反射,Perclose组1例发生较大血肿经重新加压包扎后消失.Angio-Seal组2例封闭穿刺后局部渗血.结论:Angio-Seal与Percloser两种血管封堵器均可用于冠状动脉造影与经皮冠状动脉腔内成形及支架置入后股动脉穿刺点的闭合和止血,安全有效且并发症少,但在止血时间上Angio-Seal优于Pcrcloscr.     

心导管术中Angio-Seal血管堵闭器的应用和护理

Angio-Seal血管堵闭器是一种带有腔内锚状物的闭合性止血装置,能明显减少心导管术后患者因卧床制动导致的腰酸背痛和穿刺血管的并发症。本院自2004年起应用Angio-Seal血管堵闭器,现将应用体会和护理报告如下。     

Percolse、Angio-Seal血管闭合器与人工压迫止血在急诊冠脉介入治疗中的应用

目的评价Percolse、Angio-Seal血管闭合器与人工压迫止血在急诊冠脉介入治疗中安全性和有效性。方法603例接受急诊冠脉介入治疗的患者分为人工压迫组160例、Perclose组237例和Angio-Seal组206例,观察各组止血时间、制动时间及血管并发症的发生情况。结果血管闭合器各组止血时间和制动时间明显短于人工压迫组(均P<0.01);血管并发症的发生率明显低于人工压迫组(均P<0.01);Perclose组与Angio-Seal组比较无显著性差异(P>0.05);各组间止血成功率比较无显著性差异(P>0.05)。结论急诊冠脉介入治疗中应用Perclose和Angio-Seal血管闭合器是安全、可靠的止血方法。     

3例应用Angio-Seal血管封堵器后并发急性下肢动脉栓塞患者的护理

报告3例神经外科介入手术患者,应用Angio-Seal血管封堵器后并发急性下肢动脉栓塞的护理。介入手术前全面评估患者是否存在并发急性下肢动脉栓塞的危险因素、术后注意观察相关症状是预防的重点。一旦发生,除患肢护理外,应积极配合医生做好取栓术的准备,术后加强患肢观察,警惕动脉缺血性再灌注综合征及出血的发生。     

可吸收胶原生物材料封阻穿刺口两侧血管壁与人工止血的效果比较

目的评价在冠状动脉介入诊疗术后,应用Angio-Seal血管闭合器止血的安全性及有效性。方法①选择2003-08/2005-12绵阳市中心医院心内科经股动脉穿刺行冠状动脉介入诊疗的患者212例,随机数字表法分为两组:血管闭合器止血组98例,人工压迫止血组114例。两组在年龄、性别以及动脉鞘尺寸等方面差异均无显著性意义。②血管闭合器止血组冠状动脉造影或介入治疗术后即刻拔除动脉鞘管,根据动脉鞘的尺寸选用适当规格的Angio-Seal血管闭合器止血。人工压迫止血组冠状动脉造影或介入治疗术后6h拔除动脉鞘管,人工压迫止血。③记录两组止血时间、肢体制动时间、止血时的血管迷走反应、术后1周内血管并发症的发生率。结果①血管闭合器止血组98例患者,96例成功,成功率97.9%。3例穿刺处出血,1例假性动脉瘤形成。冠状动脉造影止血时间(0.58±0.23)min,下肢制动时间(2.5±0.6)h;冠状动脉介入治疗止血时间(0.67±0.40)min,下肢制动时间(4.4±0.7)h;术后1周内血管并发症的发生率为4.1%。②人工压迫止血组114例患者,止血成功率100%。3例发生穿刺处血肿,2例假性动脉瘤形成,9例发生血管迷走反射。冠状动脉造影止血时间(12.4±6.5)min,下肢制动时间(17.2±5.3)h;冠状动脉介入治疗止血时间(28.3±9.4)min,下肢制动时间(20.4±4.6)h;术后1周内血管并发症的发生率为4.4%。结论采用Angio-Seal闭合器止血安全有效,较手压止血明显缩短了止血时间及制动时间,未增加穿刺部位血管并发症,并有减少血管迷走反射发生的可能性。     

A randomised controlled trial comparing the routine use of an Angio-Seal STS device strategy with conventional femoral haemostasis methods in a district general hospital

Femoral artery closure devices reduce the time to haemostasis and ambulation. Most district general hospitals (DGHs) now perform day case angiography on site. The purpose of this study was to assess the Angio-Seal self-tightening suture (STS) device in comparison with manual compression in this environment. A prospective randomised controlled trial was undertaken comparing the Angio-Seal STS device with manual pressure recording complications, time from end of procedure and patient satisfaction in a DGH setting. Angiography lists of 206 patients undergoing day case diagnostic cardiac catheterisation with a five French sheath at a DGH were randomised by intention to treat to receive either manual compression or a six French Angio-Seal STS device. Time from sheath removal to mobilisation, complication rate and patient satisfaction were compared. There were no significant differences between the two groups in terms of demographics (manual compression: Angio-Seal; male (%) 58 vs. 57, age (years) 65.4 vs. 66.3, body mass index (kg/m(2)) 27.7 vs. 27.5). Despite randomisation, only 74 of 107 patients in the Angio-Seal group actually had a device deployed. Angio-Seal use was associated with significantly shorter times to mobilisation (87.6 vs. 144.1 min; p < 0.001), significantly less bruising (bruise size at 1 week (28.5 vs. 82.5 cm(3); p < 0.01) and no increase in vascular complications. In addition, patients were more satisfied with Angio-Seal devices in terms of length of immobility. The routine use of Angio-Seal closure devices result in earlier mobilisation, less bruising, increased patient satisfaction with no increase in other complications in comparison to manual pressure.     

The Angio-Seal arterial closure device for early ambulation after elective percutaneous coronary intervention in patients receiving low-dose enoxaparin

This study evaluated the efficacy and safety of use of the Angio-Seal vascular closure device deployment for early ambulation (2 h) after elective percutaneous coronary intervention in 143 consecutive patients receiving either intravenous low-dose enoxaparin (0.5 mg/kg) or unfractionated heparin (UFH). The initial success rate of Angio-Seal(trade mark) deployment was 98.6%, with no significant difference between the UFH group (98.9%) and the enoxaparin group (98.0%). In-hospital and clinic outcomes were evaluated in the 141 patients with successful Angio-Seal deployment. During hospitalization, there were no deaths, myocardial infarction, urgent target vessel revascularization or bleeding events in either group; three patients in the UFH group and none in the enoxaparin group had minor vascular complications (differences not significant). In clinic follow-up, two patients in the UFH group and none in the enoxaparin group had major vascular complications (differences not significant). Routine use of the Angio-Seal(trade mark) for early ambulation in patients receiving intravenous low-dose enoxaparin compared with UFH provides promising efficacy and safety for daily practice.     

Sequential retroperitoneal venous hemorrhage and embolism of an angio-seal puncture closure device complicating iliac artery angioplasty.

PURPOSE: To present a case of iatrogenic puncture closure device embolization complicating surgery for retroperitoneal hemorrhage (RPH) secondary to angioplasty-induced common iliac vein trauma. METHODS AND RESULTS: A 78-year-old woman with rest pain underwent successful kissing balloon dilation of her aortoiliac bifurcation for a calcified ostial stenosis of the left common iliac artery. Hemostatic puncture closure devices (Angio-Seal) were used to secure both femoral punctures. A right-sided retroperitoneal hematoma developed, and during surgical exploration of the right groin, the Angio-Seal device was removed. The only bleeding site found was the external iliac artery puncture and it was repaired. She again became hypovolemic 18 hours later and was returned to surgery, where bilateral groin explorations and laparotomy by the vascular surgical team found a tear in the left common iliac vein. After repair, the patient was stable for 48 hours when the left leg became critically ischemic. Angiography detected a new high-grade stenosis in the left profunda femoris artery; embolectomy retrieved a footplate from the left puncture closure device. The patient died 11 days later from multiorgan failure. CONCLUSIONS: RPH should be considered early as an occult cause of hypovolemic shock developing soon after even technically straightforward iliac angioplasty. Interventionists should be aware that using the Angio-Seal device risks acute limb ischemia if footplate embolization occurs.     

血管封堵器应用于老年冠心病介入术后的观察与护理

目的　介绍血管封堵器在老年冠心病介入术后止血的效果观察与护理 ,并与传统的砂袋压迫止血相比较。方法　使用封堵器止血和随机抽出传统的使用砂袋压迫止血各30例 ,观察并比较止血时间、卧床时间、术后不良反应在两组中的差异。采用SPSS 10 0统计软件分析。结果　封堵器止血时间与卧床时间较砂袋压迫止血明显缩短 ,并发症减少 ,病人舒适。差异具有极其显著性 (P <0 0 0 1)。结论　老年病人使用封堵器止血后 ,止血快 ,卧床时间缩短 ,安全 ,可吸收 ,并发症减少     

Safety and efficacy of femoral artery closure with the FemoSeal(R) device after coronary angiography using a 7 French sheath

Post-cardiac catheterization femoral artery hemostasis can be accomplished with several mechanisms, including the FemoSeal? hemostasis device which has been designed and approved for closure of 6 French (F) arterial puncture sites. The aim of this study was to investigate whether the FemoSeal? vascular closure device can effectively and safely seal 7F arterial puncture sites after diagnostic and interventional cardiac catheterizations. Femoral artery puncture sites of 50 consecutive patients undergoing cardiac catheterization were closed with the FemoSeal? vascular closure device, according to the manufacturer's instructions. Efficacy endpoints were time to hemostasis and successful ambulation. Safety endpoints included bleeding complications, vessel occlusion and pseudoaneurysms. Mean time to hemostasis was 57.8±26.3 seconds (0-125 seconds). Hemostasis was achieved in 100 percent of the 50 patients. One patient suffered minor bleeding the next day, i.e. local hematoma. This clinical study demonstrates that the FemoSeal? vascular closure device, initially approved for closure of 6F arterial puncture sites, shows promising efficacy and safety to seal a larger (7F) femoral arterial puncture sites after diagnostic and interventional cardiac catheterizations.     

The frequency of vascular complications associated with the use of vascular closure devices varies by indication for cardiac catheterization

Objective

This study aimed at exploring access site-related vascular complication rates associated with the use of the vascular closure device (VCD) Angio-Seal? in an unselected patient population undergoing elective as well as emergency coronary angiography or intervention.

Background

The VCD Angio-Seal? is widely used to achieve hemostasis after diagnostic and interventional cardiac procedures. There are only little data on the frequency of vascular complications after the use of the VCD Angio-Seal? in patients in non-elective settings.

Method

In-hospital vascular complications were prospectively assessed in 4,653 consecutive cardiac catheterization procedures, which included 2,772 elective diagnostic and 960 elective percutaneous coronary interventions (PCI), and 921 emergency cardiac catheterizations in patients with NSTEMI/STEMI. In 2,077 procedures manual compression (MC) and in 2,576 procedures VCD was applied. Complication rates for manual compression and VCD use were studied and multivariate analyses performed to disclose predictors for access site-related vascular complications.

Results

Vascular complication rates in patients receiving MC to achieve hemostasis were similar to those receiving a VCD (MC 3.4% vs. VCD 3.2%, p?=?n.s.). Separate analysis of vascular complication rates for subgroups revealed a significant reduction in vascular complications for the PCI group using a VCD (MC 7.7% vs. VCD 3.2%, p?=?0.003). In emergencies VCD use lead to a rise in vascular complications (MC 0.9% vs. VCD 6.3%, p?<?0.001).

Conclusions

In contrast to elective settings, the risk of access site-related vascular complications is significantly increased after application of the VCD Angio-Seal? in patients undergoing emergency catheterizations for NSTEMI/STEMI compared with manual compression.     

比较血管闭合装置与人工压迫止血在股动脉穿刺止血中的作

目的 探讨经股动脉血管造影和血管腔内治疗后运用三种血管闭合装置进行止血的安全性和有效性,并与传统人工压迫止血进行比较.方法 2010 年2 月～2011 年3 月,495 例患者接受了经股动脉血管造影和血管腔内治疗.其中男274 例,女221 例,平均年龄65.7±11.4 岁.根据拔鞘后止血方法,患者分为4 组.人工压迫止血组386 例,Angio-Seal 封堵器组21 例,Proglide 缝合器组45 例,Starclose 闭合器组43 例.观察记录各组止血、制动时间及术后并发症,比较各组的特点.结果 血管闭合器组平均压迫时间（3.4±0.7 min）及制动时间（2 h）均较人工压迫组平均压迫时间（16.2±1.8min）及制动时间（8 h）有显著缩短（P ＜ 0.01）,而术后各类并发症无明显增加.三类血管闭合装置的止血时间、技术成功率及术后并发症无显著性统计学差异（P ＞ 0.05）.3 例10F 以上血管鞘通过2 把Proglide血管缝合器完成皮下穿刺点缝合.结论 运用血管闭合装置可有效减少止血和制动时间,其术后并发症较人工压迫无明显增加.另外运用多把Proglide 可完成对≥10F 血管鞘的闭合止血.由于三种血管闭合装置在操作方法、适应范围上各具特点,可针对不同患者的血管特点及血管鞘直径,合理选择各类血管闭合装置.     

Suture-mediated percutaneous closure of the arterial puncture site after abdominal aortic stent implantation

Summary

We report the use of a vascular surgical device to provide safe closure of the arterial access site after abdominal aortic-stent implantation. After suture-mediated percutaneous closure of the arterial puncture site, bleeding stopped immediately. There was no need for adjunctive compression. Immobilisation of the patient lasted only 1 h.