| 动脉粥样硬化抗炎治疗的研究进展 |
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| 引用本文： | 朱迪,曹烨民.动脉粥样硬化抗炎治疗的研究进展[J].中国现代医学杂志,2023(5):50-55. |
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| 作者姓名： | 朱迪 曹烨民 |
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| 作者单位： | 上海中医药大学附属上海市中西医结合医院 脉管病科， 上海 200082 |
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| 基金项目： | 国家科技重大专项（No：2019ZX09201004-002-091）；国家自然科学基金（No：82174382）；上海市科委科研计划项目（No：18401932900）；全国基层名老中医药专家曹烨民传承工作室建设项目[No：国中医药人教函（2021）44号] |
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| 摘 要： | 动脉粥样硬化（AS）的主要原因之一是血脂异常，许多治疗措施可以减少AS发病过程中的脂质危险因素，但仍存在风险。在过去的几十年中，炎症作为一种潜在的常见危险因素受到了广泛关注，促进着AS的发生发展，也为该病的治疗提供了更多机会。调控导致AS中各种炎症途径的药物是当前研究的主题。该文总结了近几年AS抗炎治疗药物的相关研究，包括广泛抗炎药物、靶向特定抗炎药物及中药抗炎治疗的作用机制，以期为该领域研究提供参考。
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| 关 键 词： | 动脉粥样硬化 下肢动脉硬化闭塞症 抗炎治疗 中西医结合 |
| 收稿时间： | 2022/10/28 0:00:00 |
Research progress of anti-inflammatory therapy for atherosclerosis |
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| Zhu Di,Cao Ye-min.Research progress of anti-inflammatory therapy for atherosclerosis[J].China Journal of Modern Medicine,2023(5):50-55. |
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| Authors: | Zhu Di Cao Ye-min |
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| Affiliation: | Department of Vascular Diseases, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China |
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| Abstract: | One of the main causes of atherosclerosis (AS) is dyslipidemia. Many treatments can reduce lipid risk factors in the development of AS, but significant risks still exist. In the past decades, inflammation as a potential common risk factor has attracted extensive attention, driving the occurrence and development of AS and providing more opportunities for the treatment of this disease. Drugs that modulate the various inflammatory pathways leading to AS are the subject of current research. This article summarizes the recent studies on anti-inflammatory therapy of AS, including extensive anti-inflammatory drugs, targeted specific anti-inflammatory drugs and the mechanism of anti-inflammatory therapy of traditional Chinese medicine, in order to provide reference for related research in this field. |
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| Keywords: | atherosclerosis lower extremity arteriosclerosis obliterans anti-inflammatory therapy integrated traditional Chinese and western medicine |
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