脑干听觉诱发电位对脑外伤后持续植物状态评价的意义

目的：通过脑干听觉诱发电位（brainstem auditory evoked potential, BAEP）评估颅脑外伤后持续植物状态（persistent vegetative state, PVS）患者的脑干功能。方法：对25例（50耳）PVS患者行BAEP检测，并与对照组行单因素方差分析。结果：PVS患者的BAEP异常率为80%。其改变复杂多样，主要表现为Ⅰ V各波的异常或分化不良，甚至波形缺如；Ⅰ、Ⅲ、Ⅴ波潜伏期（peak latency, PL）延长，I V波间潜伏期（Interpeak latency, IPL）延长，双侧V波潜伏期的耳间差（inter aural latency difference, ILD）增大；Ⅲ V与Ⅰ Ⅲ波IPL之比大于1。结论：PVS患者的BAEP结果呈多样性改变，反映了患者植物状态下存在不同程度的脑干损害，为其诊疗及预后判断提供了可靠的依据。

Evaluation of brainstem auditory evoked potential for patients with severe traumatic brain injury in persistent vegetative state

To study the value of brainstem auditory evoked potential (BAEP) in evaluating the function of brainstem in patients with severe traumatic brain injury in persistent vegetative state(PVS). Methods: Twenty five patients with severe traumatic brain injury in PVS were examined by BAEP and the data were compared with normal. Results: The abnormal rate of BAEP was 80%(20/25). The alterations included delay of peak latency of I, Ⅲ, and V waves, prolongation of interpeak latency between wave I and V， increase of inter aural latency difference of wave V and greater interpeak latency between Ⅲ V and I Ⅲ. Conclusion: BAEP can be used to evaluate the function of brainstem in patients with severe traumatic brain injury in PVS and provide evidences for prognosis.