| β-内酰胺类抗生素的药动学/药效学研究进展 |
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| 引用本文： | 梁蓓蓓,王睿. β-内酰胺类抗生素的药动学/药效学研究进展[J]. 中国新药杂志, 2004, 13(4): 310-313 |
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| 作者姓名： | 梁蓓蓓 王睿 |
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| 作者单位： | 解放军总医院临床药理学研究室,北京,100853 |
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| 摘 要： | 综述了β-内酰胺类抗生素的药动学/药效学(PK/PD)研究进展,主要阐述了PK/PD综合参数确立的实验证据,掌握PK/PD参数有助于抗菌药物的合理应用,提高疗效,减少不良反应.
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| 关 键 词： | β-内酰胺类抗生素 药动学 药效学 |
| 文章编号： | 1003-3734(2004)04-0310-04 |
Development in pharmacokinetics/pharmacodynamics research of beta-lactam antibiotics |
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| LIANG Bei-bei,WANG Rui. Development in pharmacokinetics/pharmacodynamics research of beta-lactam antibiotics[J]. Chinese Journal of New Drugs, 2004, 13(4): 310-313 |
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| Authors: | LIANG Bei-bei WANG Rui |
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| Abstract: | In order to promote rational use of antibiotics in clinics,reduce bacterial resistance and decrease ADRs of beta-lactam antibiotics, the recent development in pharmacokinetics/pharmacodynamics research of beta-lactam antibiotics, mainly the experimental evidences, were reviewed in this paper. |
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| Keywords: | beta-lactams antibiotics pharmacokinetics pharmacodynamics |
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