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Isolated leukemia cutis as extramedullary relapse of acute myeloid leukemia |
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| Authors: | Farinoosh Dadrass Fatema Esmail Aayushma Regmi Kumaran Mudaliar Kamran M. Mirza Ameet R. Kini Wendy Kim Patrick Hagen Nasheed M. Hossain |
| Affiliation: | 1. Loyola University Chicago Stritch School of Medicine, Loyola University Medical Center, Maywood Illinois, USA ; 2. Division of Hematology/Oncology, Department of Medicine, Loyola University Medical Center, Maywood Illinois, USA ; 3. Department of Pathology and Laboratory Medicine, Loyola University Medical Center, Maywood Illinois, USA ; 4. Division of Dermatology, Department of Medicine, Loyola University Medical Center, Maywood Illinois, USA |
| Abstract: | Acute myeloid leukemia (AML) arises from clonal expansion of malignant hematopoietic precursor cells in the bone marrow. In rare instances, AML can recur with prominent extramedullary manifestations (i.e., leukemia cutis or myeloid sarcoma), either simultaneously or preceding marrow involvement, or as a sole site of primary disease relapse. |
| Keywords: | acute myeloid leukemia AML leukemia leukemia cutis MLL gene MLL rearrangement |