| 前列舒康胶囊对前列腺炎模型大鼠及前列腺组织形态的影响 |
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| 引用本文： | 赵富虎,刘丽春,滕宝霞. 前列舒康胶囊对前列腺炎模型大鼠及前列腺组织形态的影响[J]. 中国实验方剂学杂志, 2010, 16(8): 189-192 |
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| 作者姓名： | 赵富虎 刘丽春 滕宝霞 |
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| 作者单位： | 1. 兰州太宝制药有限公司,兰州,730050
2. 甘肃省人民医院,兰州,730000 |
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| 摘 要： | 目的 :考察前列舒康胶囊对消痔灵和大肠杆菌所致大鼠前列腺炎的影响。 方法 :采用文献方法造模,连续给药30 d后观察大鼠前列腺湿重、前列腺白细胞及卵磷脂小体密度,并进行统计学处理。 结果 : 前列舒康胶囊各剂量组可明显降低模型大鼠前列腺质量和白细胞数(P<0.01),中、高剂量组可回升低下的卵磷脂小体密度(P<0.05或P<0.01),明显降低大鼠前列腺组织中炎细胞浸润和成纤维细胞增生(P<0.05)。 结论 : 前列舒康胶囊可显著改善慢性前列腺炎病组织学的异常改变;对大肠杆菌所致细菌性前列腺炎具有显著的治疗作用。
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| 关 键 词： | 前列舒康胶囊 前列腺炎 大鼠模型 |
| 收稿时间： | 2010-02-04 |
Effect of Qianlie Shukang Capsule on Pathomorphology of Prostate and the Tissues of Prostatitis in Model Rats |
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| ZHAO Fu-hu,LIU Li-chun and TENG Bao-xia. Effect of Qianlie Shukang Capsule on Pathomorphology of Prostate and the Tissues of Prostatitis in Model Rats[J]. China Journal of Experimental Traditional Medical Formulae, 2010, 16(8): 189-192 |
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| Authors: | ZHAO Fu-hu LIU Li-chun TENG Bao-xia |
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| Affiliation: | Lanzhou Taibao Pharmaceutical Co. Ltd., Lanzhou 730050, China;The people's Hospital of Gansu Province, Lanzhou 730000, China;Institute for drug Control of Gansu Province, Lanzhou 730000, China |
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| Abstract: | Objective: To investigate the effects of Qianlie Shukang Capsule in treating prostatitis. Method : Pharmacological investigations were carried out to study the impact of Qianlie Shukang Capsule on rat's prostate fribrosis inflammation caused by Xiaozhiling and on rat's prostatitis caused by Escherichia coli. Result: Qianlie Shukang Capsule has significant effect for treating prostatitis induced by Xiaozhiling and that induced by E. coli, indicated by prostate weight, leucocyte count and lecithin density(P<0.05 or P<0.01). Conclusion: Qianlie Shukang Capsule can alleviate prostate pathological changes in chronic prostatitis, and is effective in treating bacterial prostatitis incause by E. coli. |
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| Keywords: | Qianlie Shukang Capsule prostatitis rat model |
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