| 正交试验法优选冰荷洗剂水提工艺条件 |
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| 引用本文： | 刘瑞连,严建业,李顺祥,陈胜璜,罗堃.正交试验法优选冰荷洗剂水提工艺条件[J].中国中医药信息杂志,2012,19(3):56-58. |
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| 作者姓名： | 刘瑞连 严建业 李顺祥 陈胜璜 罗堃 |
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| 作者单位： | 1. 湘潭市中心医院,湖南,湘潭,411100;湖南中医药大学药学院中药现代化教育厅重点实验室,湖南,长沙,410208
2. 湖南中医药大学药学院中药现代化教育厅重点实验室,湖南,长沙,410208 |
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| 基金项目： | 湖南省中医药科研计划(2010095);国家中医药管理局重点学科项目(2009);湖南省高校科技创新团队资助项目(湘教通[2010]212号) |
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| 摘 要： | 目的优选冰荷洗剂最佳水提工艺条件。方法采用正交试验,以绿原酸浸出量、浸膏得率为指标,用多指标综合评分法进行数据处理,优化提取条件。结果最佳水提工艺为药材浸泡0.5 h,提取2次,加水量分别为10、8倍,提取时间分别为1.0、0.5 h。结论该提取工艺合理,稳定可行。
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| 关 键 词： | 冰荷洗剂 绿原酸 提取工艺 正交试验 高效液相色谱法 |
Optimization of Water Extraction Process of Binghe Lotion by Orthogonal Test |
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| LIU Rui-lian
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YAN Jian-ye
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LI Shun-xiang
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CHEN Sheng-huang
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LUO Kun.Optimization of Water Extraction Process of Binghe Lotion by Orthogonal Test[J].Chinese Journal of Information on Traditional Chinese Medicine,2012,19(3):56-58. |
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| Authors: | LIU Rui-lian YAN Jian-ye LI Shun-xiang CHEN Sheng-huang LUO Kun |
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| Institution: | Kun2(1.Xiangtan Central Hospital,Xiangtan 411100,China;2.Key Lab of Modernization of Chinese Medicine,School of Pharmacy,Hunan University of Chinese Medicine,Changsha 410208,China) |
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| Abstract: | Objective To optimize the extraction process conditions of Binghe Lotion.Methods Orthogonal test was employed for selecting the optimum extraction process by using the content of chlorogenic acid and total solid matters as indexes.Data processing was carried out with multi-index comprehensive evaluation method for optimizing the extaction condition.Results The optimum extracting condition was:soaking medical materials in water for 0.5 hour,boiling two times,1.0,0.5 hours respectively,the amount of water used was 10,8 times of the drug mixture respectively.Conclusion The optimized extraction process was practical,steady and feasible. |
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| Keywords: | Binghe Lotion chlorogenic acid extraction process orthogonal test HPLC |
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