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泮托拉唑对急性心肌梗死行经皮冠状动脉支架植入术患者消化道出血的预防
引用本文:巩晓宏,袁宇,辛渭川,刘超峰.泮托拉唑对急性心肌梗死行经皮冠状动脉支架植入术患者消化道出血的预防[J].新乡医学院学报,2012,29(5):369-371.
作者姓名:巩晓宏  袁宇  辛渭川  刘超峰
作者单位:1. 西安市中心医院心内科,陕西西安,710003
2. 新乡医学院第一附属医院心内二科,河南卫辉,453100
3. 陕西省中医医院,陕西西安,710003
摘    要:目的观察泮托拉唑在急性心肌梗死经皮冠状动脉支架植入术(PCI)治疗中对消化道出血的预防效果。方法急性心肌梗死行PCI患者87例分为观察组45例和对照组42例,对照组给予常规治疗,观察组在常规治疗基础上加用泮托拉唑,观察2组患者住院期间PCI成功率、并发症、病死率及7 d内消化道出血发生情况。结果观察组和对照组消化道出血的发生率分别为4.4%和21.4%,观察组明显低于对照组(P<0.05)。结论急性心肌梗死PCI治疗中预防性使用泮托拉唑能有效防止消化道出血的发生。

关 键 词:急性心肌梗死  经皮冠状动脉支架植入术  泮托拉唑  消化道出血

Effect of pantoprazole on alimentary tract hemorrhage in patients with acute myocardial infarction performed percutaneous coronary artery stent implantation
GONG Xiao-hong , YUAN Yu , XIN Wei-chuan , LIU Chao-feng.Effect of pantoprazole on alimentary tract hemorrhage in patients with acute myocardial infarction performed percutaneous coronary artery stent implantation[J].Journal of Xinxiang Medical College,2012,29(5):369-371.
Authors:GONG Xiao-hong  YUAN Yu  XIN Wei-chuan  LIU Chao-feng
Institution:1.Department of Cardiovasology,the Central Hospital of Xi′an City,Xi’an 710003,Shaanxi Province,China;2.Department of Cardiovasology,the First Affiliated Hospital of Xinxiang Medical College,Weihui 453100,Henan Province,China;3.Shaanxi Province Chinese Medicine Hospital,Xi’an 710003,Shaanxi Province,China)
Abstract:Objective To study the preventive effect of pantoprazole on alimentary tract hemorrhage in patients with acute myocardial infarction(AMI) performed percutaneous coronary artery stent implantation(PCI).Methods Eighty-seven patients with AMI performed PCI were divided into observation group and control group.Forty-two patients in control group were treated with conventional therapy,based on this,forty-five patients in observation group were treated with pantoprazole.The success rate of PCI,complication,case fatality rate and alimentary tract hemorrhage within seven days in two groups were observed during hospitalization.Results The rate of alimentary tract hemorrhage in observation group and control group was 4.4% and 21.4% respectively,the rate of alimentary tract hemorrhage in observation group was significantly lower than that in control group(P<0.05).Conclusion Pantoprazole can effectively prevent alimentary tract hemorrhage in patients with AMI performed PCI.
Keywords:acute myocardial infarction  percutaneous coronary artery stent implantation  pantoprazole  alimentary tract hemorrhage
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