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A case of mixed connective tissue disease complicated with thymic carcinoma and Hashimoto's thyroiditis
Authors:Yoshito Yoshidome  Shigeaki Hayashi  Yoshikazu Maruyama  Toshi Yoneda  Daisuke Matsuzoe  Takehito Kawakami  Hiroshi Shirahama  Yukie Tashiro  Nobutaka Eiraku
Institution:(1) Department of Neurology, Imakiire General Hospital, Kagoshima, Japan;(2) Department of Chest Surgery, Imakiire General Hospital, Kagoshima, Japan;(3) Department of Pathology, Imakiire General Hospital, Kagoshima, Japan;(4) Health Service Center, Kagoshima University, Kagoshima, Japan;(5) Department of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan
Abstract:We report the case of a 63-year-old woman who suffered from mixed connective tissue disease (MCTD) complicated with thymic carcinoma and Hashimoto's thyroiditis. Although many systemic syndromes associated with thymoma and thymic carcinoma, i.e., myasthenia gravis, pure red cell aplasia, hypogammaglobulinemia, and Hashimoto's thyroiditis, are known, this is the first report of MCTD complicated with thymic carcinoma. It was suggested that MCTD may be a paraneoplastic syndrome associated with thymic carcinoma.
Keywords:Hashimoto's thyroiditis  Mixed connective tissue disease  Paraneoplastic syndrome  Thymic carcinoma
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