青少年牙龈炎的临床检查和龈沟液中天冬氨酸转氨酶水平的分析

为观察青少年期牙龈炎的临床特征和龈沟液中天冬氨酸转氨酶 (GCF AST)的变化 ,选择 1 0～ 1 6岁的受试者 ,分为牙龈健康组和牙龈炎症组 ,作口腔检查 ,记录临床参数 ,收集龈沟液 (GCF) ,检测其中AST水平 ;采取龈沟细菌标本 ,镜下记录杆菌、球菌、螺旋体及梭形菌的百分计数。将 2组数据进行对比分析。青少年牙龈炎的临床检查结果为 :菌斑控制记录 (PCR) 73% ;牙垢指数 (OHI) :Ⅱ度 36 % ,Ⅲ度 6 4 % ;牙龈指数 (GI) :Ⅰ度 2 5 % ,Ⅱ度 4 3% ,Ⅲ度32 % ;出血指数 (GBI) 5 4 %。青少年牙龈炎组GCF和GCF AST明显高于健康组 (P <0 .0 1 ) ;龈沟液中螺旋体计数龈炎组显著高于健康组 ,杆菌、球菌、梭形菌计数 2组间无显著差异。提示青少年期的牙龈炎有进行性发展的危险性 ,包括向牙周炎的转变。龈沟液中AST水平与临床参数有关 ,可作为评价牙龈炎趋向性的动态指标

Relationship between Levels of Aspartate Aminotransferase Gingival Crevicular Fluid and Clinic in Adolescent Gingivitis

In order to evaluate clinical features and levels of aspartate aminotranferase(AST)in gingival crevicular fluid of gingivitis in adolescents, 21 healthy and 28 gingivitis subjects, age range from 10 to 16, were selected. The clinical parameters were examined and recorded. Within each subject, the gingival crevicular fluid(GCF)sample was collected. The value of GCF and AST were measured by biochemical analysis instrument. The clinical parameters of gingivitis in adolescents were the plaque control record(PCR): 73%, oral hygine index(OHI): Ⅱ(36%), Ⅲ(64%); gingival index(GI):Ⅰ(25%), Ⅱ(43%), Ⅲ(32%)and gingival bleeding(GBI): 54%. The amounts of GCF, GCF-AST were significantly higher in samples from gingivitis group than in the healthy group. Gingivitis in adolescents have a risk of disease progress. AST in GCF may also be a useful marker for gingivitis tendency.