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A anorectal fistula treatment with acellular extracellular matrix: A new technique
作者姓名:Song WL  Wang ZJ  Zheng Y  Yang XQ  Peng YP
摘    要:AIM: To investigate a new technique of the anorectal fistula treatment with acellular extracellular matrix (AEM). METHODS: Thirty patients with anorectal fistula were treated with AEM. All fistula tracts and primary openings were identified using conventional fistula probe. All tracts were curet-ted with curet and irrigated with hydrogen peroxide and metronidazole. The AEM was pulled into the fistula tract from secondary to primary opening. The material was secured at the level of the primary opening. The excess AEM was trimmed at skin level at the secondary opening. RESULTS: All of the 30 patients had successful closure of their fistula after a 7-14 d follow-up. The healing rate of anal fistula in treatment group was 100%. The ache time, healing time and anal deformation of treatment group were obviously superior to traditional surgical methods. CONCLUSION: Using AEM anal fistula plug in treatment that causes the anorectal fistula is safe and successful in 100% of patients. It can reduce pain, shorten disease course and protect anal function.

关 键 词:肛门直肠瘘  非细胞外间质  治疗方法  消化道疾病
收稿时间:2008 Jan 17

An anorectal fistula treatment with acellular extracellular matrix: a new technique
Song WL,Wang ZJ,Zheng Y,Yang XQ,Peng YP.An anorectal fistula treatment with acellular extracellular matrix: a new technique[J].World Journal of Gastroenterology,2008,14(30):4791-4794.
Authors:Song Wei-Liang  Wang Zhen-Jun  Zheng Yi  Yang Xin-Qing  Peng Ya-Ping
Institution:Department of General Surgery,Chaoyang Hospital of Capital Medicine University,Beijing 100020,China
Abstract:AIM:To investigate a new technique of the anorectal fistula treatment with acellular extracellular matrix (AEM).METHODS: Thirty patients with anorectal fistula were treated with AEM.All fistula tracts and primary openings were identified using conventional fistula probe.All tracts were curetted with curet and irrigated with hydrogen peroxide and metronidazole.The AEM was pulled into the fistula tract from secondary to primary opening.The material was secured at the level of the primary opening.The excess AEM was trimmed at skin level at the secondary opening.RESULTS: All of the 30 patients had successful closure of their fistula after a 7-14 d follow-up.The healing rate of anal fistula in treatment group was 100%.The ache time,healing time and anal deformation of treatment group were obviously superior to traditional surgical methods.CONCLUSION: Using AEM anal fistula plug in treatment that causes the anorectal fistula is safe and successful in 100% of patients.It can reduce pain,shorten disease course and protect anal function.
Keywords:Acellular extracellular matrix  Anorectal fistula
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