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Cytogenetic studies on acute monocytic leukemia |
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| Authors: | Roland Berger Alain Bernheim Hans-Josef Weh Marie-Thèrèse Daniel Georges Flandrin |
| Affiliation: | 1. Laboratoire de Cytogénétique, Centre G. Heym, UER d''Hématologie, Hôpital Saint-Louis, Paris, France;2. Laboratoire d''Hématologie, Centre G. Hayem, UER d''Hématologie, Hôpital Saint-Louis, Paris, France |
| Abstract: | Chromosome studies were performed on ten acute monocytic leukemias of which seven were poorly differentiated and three well differentiated. Chromosome abnormalities were found in 8 cases. Rearrangements of chromosome 11 were observed in 5/7 of the poorly differentiated cases. Although not specific, chromosome 11 rearrangements appear to be abnormally frequent in poorly differentiated acute monocytic leukemias. |
| Keywords: | Acute monocytic leukemia Chromosome abnormalities acute leukemia acute myeloblastic leukemia acute monocytic leukemia French-American-British Cooperative Group acute lymphoblastic leukemia acute myelomonocytic leukemia chronic lymphocytic leukemia chronic myeloid leukemia erythroleukemia C bands by barium hydroxide using Giemsa G bands by trypsin using Giemsa R bands by beating using Giemsa Fibrinogen degradation products |
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