| 家蝇对高效氯氰菊酯抗药性机制的探索 |
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| 引用本文： | 胡文涛.家蝇对高效氯氰菊酯抗药性机制的探索[J].中华卫生杀虫药械,2008,14(2):87-91. |
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| 作者姓名： | 胡文涛 |
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| 作者单位： | 北京市第五十五中学,北京,100020 |
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| 摘 要： | 目的研究揭示家蝇对高效氯氰菊酯抗药性机制。方法生物测定、遗传学、生物化学以及分子生物学方法。结果经过25代选育，选育品系家蝇对高效氯氰菊酯抗性高达4419．07倍；抗性遗传为隐性遗传；抗性家蝇羧酸酯酶比活力是敏感家蝇的2．436倍；抗性品系的钠离子通道基因发现了2个氨基酸的改变。结论家蝇对高效氯氰菊酯抗性可能与钠离子通道基因的突变有关。
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| 关 键 词： | 家蝇 高效氯氰菊酯 遗传学 抗性机制 |
| 文章编号： | 1671-2781(2008)02-0087-05 |
| 修稿时间： | 2007年10月20 |
Resistance mechanisms of Musca domestica against beta-cypermethrin |
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| HU Wen-tao.Resistance mechanisms of Musca domestica against beta-cypermethrin[J].Chinese Journal of Hygienic Insecticides and Equipments,2008,14(2):87-91. |
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| Authors: | HU Wen-tao |
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| Institution: | HU Wen-tao ( No. 55 High School of Belting, Belting 100020, China) |
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| Abstract: | Objective To explore the mechanism of Musca domestica, and its resistant against beta-cypermethrin. Methods Bioassay, heredity, biochemistry and molecular methods. Results The selected house fly strains developed 4 419.07 folds resistance against beta-cypermethrin after twenty five generations of successive selection. The resistance heredity was recessive. The activity of carbroxylesterases of the resistant strains was 2. 436 times higher than that of the susceptible strain. There were two amino acid replacements in the sodium channel of the resistant strain. Conclusion The gene mutants in the sodium channel were possibly the main cause for the resistance of house flies against beta-cypermethrin. |
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| Keywords: | Musca domestica beta-cypermethrin heredity resistance mechanism |
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