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The relationship between the expression of tumor matrix-metalloproteinase and the characteristics of magnetic resonance imaging of human gliomas
Authors:Lihua Liu  Ming Zhang  Yuan Wang and Min Li
Institution:Lihua Liu,Ming Zhang,Yuan Wang,Min Li Center of Image,the First Affilliated Hospital to Medical College of Xi'an Jiaotong University,Xi'an,Shaanxi Province 710061,China
Abstract:Objective:To investigate the relationship between the expression level of matrix-metalloproteinases (MMPs) with the pathological grades and MRI characteristics of human gliomas. Methods: Prior pre-and post-contrast enhancement MRI was performed on 31 patients with gliomas, which were confirmed by post-operational pathology. The expression of MMP-2 and MMP-9 were determined by immunohistochemical staining in both a low grading group (grades I and II, n=20) and high grading group (grades III and IV, n=11). Re...
Keywords:matrix-metalloproteinase  magnetic resonance imaging  glioma  
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