The relationship between the expression of tumor matrix-metalloproteinase and the characteristics of magnetic resonance imaging of human gliomas |
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Authors: | Lihua Liu Ming Zhang Yuan Wang and Min Li |
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Institution: | Lihua Liu,Ming Zhang,Yuan Wang,Min Li Center of Image,the First Affilliated Hospital to Medical College of Xi'an Jiaotong University,Xi'an,Shaanxi Province 710061,China |
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Abstract: | Objective:To investigate the relationship between the expression level of matrix-metalloproteinases (MMPs) with the pathological grades and MRI characteristics of human gliomas. Methods: Prior pre-and post-contrast enhancement MRI was performed on 31 patients with gliomas, which were confirmed by post-operational pathology. The expression of MMP-2 and MMP-9 were determined by immunohistochemical staining in both a low grading group (grades I and II, n=20) and high grading group (grades III and IV, n=11). Re... |
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Keywords: | matrix-metalloproteinase magnetic resonance imaging glioma |
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