| 小剂量甘氨双唑钠在中晚期肺癌介入化疗中的增敏作用 |
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| 引用本文： | 曹跃勇,朱军,贾钰铭,雷开键. 小剂量甘氨双唑钠在中晚期肺癌介入化疗中的增敏作用[J]. 泸州医学院学报, 2008, 31(4) |
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| 作者姓名： | 曹跃勇 朱军 贾钰铭 雷开键 |
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| 作者单位： | 1. 宜宾市第二人民医院,介入中心,四川宜宾644000
2. 宜宾市第二人民医院,肿瘤科,四川宜宾644000 |
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| 摘 要： | 目的:探讨小剂量甘氨双唑钠(CMNa)在中晚期肺癌介入化疗中的增敏作用,并通过观察疗效和毒副作用评价其临床应用、推广价值.方法:总结我院2005年至今行支气管动脉灌注化疗的中晚期肺癌患者106例,按照随机分为试验组(A组)和对照组(B组),其中A组灌注化疗药物前注入CMNa 0.25g,B组仅单纯灌入化疗药物.两组间手术方式及化疗方案无差异.术后定期随访影像学及临床资料,进行统计学分析比较.结果:A组肿瘤治疗有效率高于B组,两组差异有统计学意义(P<0.05);两组均有一定程度的化疗后毒副反应,组间比较无统计学差异.结论:介入治疗中小剂量甘氨双唑钠有化疗增敏作用,可以提高肺癌化疗效果,且不增加化疗毒副作用,值得临床推广和应用.
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| 关 键 词： | 甘氨双唑钠 介入 肺癌 |
SENSITIVITY-ENHANCING ACTION OF LOW DOSE CMNA ON PATIENTS WITH ADVANCED LUNG CARCINOMA DURING INTERVENTION CHEMOTHERAPY |
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| Cao Yueyong,et al. SENSITIVITY-ENHANCING ACTION OF LOW DOSE CMNA ON PATIENTS WITH ADVANCED LUNG CARCINOMA DURING INTERVENTION CHEMOTHERAPY[J]. Journal of Luzhou Medical College, 2008, 31(4) |
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| Authors: | Cao Yueyong et al |
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| Affiliation: | Cao Yueyong,et al Department of Radiation,the No.2 People's Hospital of Yibin City |
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| Abstract: | Objective:To explore whether low dose Sodium Glycididazole(CMNa) used before intervention chemotherapy for advanced lung cancer patients can enhance the chemo-sensitivity and its side effects.Methods:106 cases of advanced lung cancer patients treated by intervention chemotherapy through bronchial artery,collected since 2005 were randomly divided into two groups: experimental group(group A),0.25g CMNa was administered before chemical drugs;control group(group B),chemical drugs only.There were no differences ... |
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| Keywords: | Sodium Glycididazole(CMNa) Intervention Lung cancer |
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