年轻与中老年子宫颈癌患者的临床与病理特征比较

目的:比较年轻子宫颈癌患者与中老年子宫颈癌患者的临床和病理特征。方法:回顾分析301例子宫颈癌患者的临床资料。比较年轻组(年龄≤35岁)和中老年组(年龄>35岁)患者的临床及病理特征。结果:301例子宫颈癌患者平均发病年龄为(45.07±0.52)岁,发病高峰年龄为35～46岁(54.2%);年轻组43例(14.3%),中老年组258例(85.7%)。所有患者中,多孕(G≥3次)170例(56.5%);多产(P≥2次)102例(33.9%)。临床表现以接触性出血及不规则阴道出血为主,中老年组无症状体检发现的比例较年轻组高(26.0%比20.9%)。年轻组腺癌构成比(16.3%)高于中老年组腺癌构成比(6.7%)(P<0.05)。年轻组以Ia期占44.2%,中老年组占25.6%(P<0.05)。在病理特征方面,年轻组发生淋巴转移的比例以及脉管浸润、宫旁浸润和间质浸润的深度均低于中老年组。结论:年轻子宫颈癌患者较中老年子宫颈癌患者肿瘤的临床分期早,腺癌发生率高。

Clinical Analysis of 301 Patients with Cervical Carcinoma

Objective：To compare the clinical symptoms and pathological features of cervical cancer in different age types.Methods： A total of 301 patients with cervical cancer were reviewed.The patients were divided into two groups： young group（age,≤35 years） and old group（age,〉35 years）.Results： The average age was 45.07±0.52 years and the peak age was 35-46 years（54.2%）.The proportion of patients with constant pregnancy（G≥3） and constant giving-birth（P≥2） were 56.5% and 33.9%,respectively.The proportion of stage Ia in the young group（44.2%） was higher than that in the old group（25.6%）.The rate of adenocarcinoma was 16.3% in the young group but 6.7% in the old group（P〈0.05）.The rate of lymph node metastases was lower in the young group than that in the old group.The depths of vascular invasion,parametrium invasion and stromal invasion in the young group were less than those in the old group.Conclusions： In the young group,the clinical stage of cervical cancer is earlier than that in the old group,and the rate of adenocarcinoma is higher than that in the old group.