| ADENOVIRUS-MEDIATED EXPRESSION OF PEX, A NONCATALYTIC FRAGMENT OF MATRIX METALLOPROTEINASE-2, AND IT’S INHIBITION ON ANGIOGENESIS AND TUMOR GROWTH |
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| 引用本文： | 李金萍,胡颖,林仲翔,张志谦.ADENOVIRUS-MEDIATED EXPRESSION OF PEX, A NONCATALYTIC FRAGMENT OF MATRIX METALLOPROTEINASE-2, AND IT’S INHIBITION ON ANGIOGENESIS AND TUMOR GROWTH[J].中国癌症研究,2006(1). |
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| 作者姓名： | 李金萍 胡颖 林仲翔 张志谦 |
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| 作者单位： | Department of Cell Biology Beijing Institute for Cancer Research Peking University School of Oncology Beijing 100036，Department of Cell Biology Beijing Institute for Cancer Research Peking University School of Oncology Beijing 100036，Department of Cell Biology Beijing Institute for Cancer Research Peking University School of Oncology Beijing 100036，Department of Cell Biology Beijing Institute for Cancer Research Peking University School of Oncology Beijing 100036 |
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| 基金项目： | This work was supported by the NationalNatural Science Foundation of China (No. 39889916), theNational “973” Program of China (No. G2000057002), theNatural Science Foundation of Beijing (No. 7002009)Peking University Human Disease Center Project(2000-A-28) and Grant (No.1998-10). |
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| 摘 要： | Angiogenesis, the sprouting of new blood vessels from existing vessels, is a crucial process during embryogenesis, wound healing, and in the female reproductive organs1]. A growing number of diseases,including cancer and inflammatory disorders, are characterized by excessive, de-regulated angiogenesis2], attributable to increased production of growth factors or to decreased production of angiogenesis inhibitors3]. Recently, a number of endogenous angiogenesis inhibitors have been identified…
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