| Abstract: | AIM: To determine a therapeutic effect of normodipin on intravascular platelet activity in patients with arterial hypertension (AH) and metabolic syndrome (MS). MATERIAL AND METHODS: Twenty patients received normodipin for one month in a dose 10 mg/day. The drug activity was assessed by dynamics of anthropometric indices, lipid spectrum of the blood, lipid peroxidation in plasma and platelets, antioxidant protection of blood liquid and platelets, intravascular platelet activity. The results were processed statistically. RESULTS: Normodipin in hypertensive patients with MS has a positive effect on peroxidation and platelet aggregation. Long-term normodipin administration promoted stabilization of the effect. CONCLUSION: To reduce body mass in hypertensive patients with MS it is necessary to combine normodipin administration with nonpharmacological medication. |
