非淋菌性泌尿生殖道炎支原体检测及药敏分析

目的了解支原体在性病患者中的感染及耐药情况。方法应用支原体鉴定定量和药敏试条，对12528例怀疑性病患者，分成5个年龄组取材做支原体培养和药敏试验。结果在这些患者中，支原体阳性率为75.3%(9433/12528)，其中解脲脲原体(Uu)58.3%(7305例)，显著高于人型支原体(Mh)阳性率3.0%(379例)和Uu＋Mh阳性率14.0%(1749例)，阳性率比较P＜0.01；药物不敏感情况依次为氧氟沙星50.5%、红霉素41.9%、四环素14.6%、强力霉素4.7%、交沙霉素2.9%和原始霉素2.0%。结论非淋菌性泌尿生殖道炎仍以Uu感染为主，集中于21～40岁；支原体感染药物不敏感情况严重；同时进行支原体培养和药敏实验对临床用药具有重要意义。

Mycoplasma Detection of the OPD patients with Non-gonococcal Genitourinary Tract Infection and Drug Sensitive Analysis of 6 Antibiotics

Objective: To explore the infection of mycoplasma in the venereal diseases and information about their drug susceptibility. Methods: Materials from the 12 528 patients were cultivated and drug susceptibility made testing was made using the mycoplasma IST Kit. Results: The results showed that 9433 of 12 528 (75.3%)were infected by mycoplasma, Uu infective rate 58.3 % (7 305 cases)was found significantly higher than Mh infective rate 3.0%(379 cases)and mixed infection of both Uu and Mh was 14.0%(1 749 cases,)P<0.01. The no susceptible conditions were in turn that ofloxacine(50.5%), Erythromycine(41.9%), tetracycline(14.6%), doxycycline(4.7%), josamycine(2.9%), and pristinamycine(2.0%) respectively. Conclusions:The results suggested that non-gonococcal genitourinary tract infection was firstly ureaplasma urealyticum, concentracted infection was at age 21-40 years. no susceptible stat of mycoplasma infection to drug was serious, so that susceptibility testing of mycoplasma had a important significance to clinical drug treatment.