Clinically important molecular features of Peruvian colorectal tumours: high prevalence of DNA mismatch repair deficiency and low incidence of KRAS mutations |
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| Authors: | Egoavil C M Montenegro P Soto J L Casanova L Sanchez-Lihon J Castillejo M I Martinez-Canto A Perez-Carbonell L Castillejo A Guarinos C Barbera V M Jover R Paya A Alenda C |
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| Affiliation: | Oncología Molecular, Hospital Universitario Elche, Spain. |
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| Abstract: | |
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| Keywords: | BRAF mutations colorectal cancer DNA mismatch repair deficiency microsatellite instability v-raf murine sarcoma viral oncogene homolog B1 CRC" },{" #name" :" keyword" ," $" :{" id" :" kw0045" }," $$" :[{" #name" :" text" ," _" :" colorectal cancer epidermal growth factor receptor v-Kiras2 Kirsten rat sarcoma viral oncogene homolog INEN" },{" #name" :" keyword" ," $" :{" id" :" kw0070" }," $$" :[{" #name" :" text" ," _" :" National Cancer Institute, Peru LOE" },{" #name" :" keyword" ," $" :{" id" :" kw0080" }," $$" :[{" #name" :" text" ," _" :" loss of expression mBG" },{" #name" :" keyword" ," $" :{" id" :" kw0090" }," $$" :[{" #name" :" text" ," _" :" modified Bethesda guidelines mutL homolog 1 mutS homolog 2 mutS homolog 6 MSI" },{" #name" :" keyword" ," $" :{" id" :" kw0130" }," $$" :[{" #name" :" text" ," _" :" microsatellite instability MMR" },{" #name" :" keyword" ," $" :{" id" :" kw0230" }," $$" :[{" #name" :" text" ," _" :" mismatch repair postmeiotic segregation increased 2 TMA" },{" #name" :" keyword" ," $" :{" id" :" kw0155" }," $$" :[{" #name" :" text" ," _" :" tissue microarray |
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