Drug immunosuppression therapy for adult heart transplantation. Part 2: clinical applications and results |
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| Authors: | Mueller Xavier M |
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| Affiliation: | Department of Cardiovascular Surgery, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada. xavier.mueller@usherbrooke.ca |
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| Abstract: | This review describes the clinical application of classical immunosuppressive drugs as well as that of more recent drugs. All current immunosuppressive drugs target T-cell activation, and cytokine production and clonal expansion, or both. Immunosuppressive protocols can be broadly divided into induction therapy, maintenance immunosuppression, and treatment of acute rejection episodes. |
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| Keywords: | 34 |
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