| 实时心肌超声造影评价冠状动脉不同狭窄程度患者心肌血流灌注 |
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| 引用本文： | 李燕,吕清,王新房,王静,丁尚伟,陈明,张静. 实时心肌超声造影评价冠状动脉不同狭窄程度患者心肌血流灌注[J]. 中国医学影像技术, 2008, 24(12): 1955-1958 |
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| 作者姓名： | 李燕 吕清 王新房 王静 丁尚伟 陈明 张静 |
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| 作者单位： | 华中科技大学同济医学院附属协和医院超声影像科,湖北武汉,430022 |
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| 摘 要： | 目的探讨静息状态下经静脉实时心肌超声造影(RT-MCE)评价冠脉不同狭窄程度患者心肌血流灌注的临床价值。方法根据冠状动脉(CA)造影结果,按CA狭窄程度将其所供应的心肌节段分为A组、B组及C组,其中C组再按有无冠状动脉侧支循环分成有侧支循环形成的C1组及无侧支循环形成的C2组。对25例冠心病患者及16例年龄相匹配的健康志愿者行RT-MCE,从MCE再灌注充盈曲线获得平台期峰值强度(A值)和曲线上升斜率(β值)分析心肌灌注。结果定性分析:病例组中有271个心肌节段MCE表现为灌注良好,81个心肌节段MCE表现为低灌注。定量分析:①A组及C1组的A值、β值及A×β值与对照组相比,差异均无统计学意义(P>0.05);②B组及C2组的β值、A×β值明显低于对照组,与对照组相比(β值分别为0.67±0.57vs0.97±0.65,0.65±0.80vs0.97±0.65;A×β值分别为4.51±3.89vs6.86±5.61,3.18±3.10vs6.86±5.61,P<0.05)。③当无侧支循环开放时,β及A×β值均随着CA狭窄程度加重呈不同程度递减,侧支循环开放,可能会高估CA狭窄时的心肌血流灌注。结论在静息状态下,RT-MCE可较好地发现冠状动脉狭窄程度>75%的心肌血流灌注异常。
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| 关 键 词： | 心肌 超声心动描记术 冠状动脉狭窄 灌流 |
| 收稿时间： | 2008-06-11 |
| 修稿时间： | 2008-09-07 |
Myocardial perfusion in patients with different graded coronary stenosis by real-time myocardial contrast echocardiography |
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| LI Yan,LV Qing,WANG Xin-fang,WANG Jing,DING Shang-wei,CHEN Ming and ZHANG Jing. Myocardial perfusion in patients with different graded coronary stenosis by real-time myocardial contrast echocardiography[J]. Chinese Journal of Medical Imaging Technology, 2008, 24(12): 1955-1958 |
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| Authors: | LI Yan LV Qing WANG Xin-fang WANG Jing DING Shang-wei CHEN Ming ZHANG Jing |
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| Affiliation: | Department of Ultrasound, Union Hospital, Tong Ji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China;Department of Ultrasound, Union Hospital, Tong Ji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China;Department of Ultrasound, Union Hospital, Tong Ji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China;Department of Ultrasound, Union Hospital, Tong Ji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China;Department of Ultrasound, Union Hospital, Tong Ji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China;Department of Ultrasound, Union Hospital, Tong Ji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China;Department of Ultrasound, Union Hospital, Tong Ji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China |
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| Abstract: | |
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| Keywords: | Myocardium Echocardiography Coronary stenosis Perfusion |
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