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人脐带眼科用透明质酸的制备和分析检验
引用本文:沈渤江,张天民. 人脐带眼科用透明质酸的制备和分析检验[J]. 山东大学学报(医学版), 1985, 0(4)
作者姓名:沈渤江  张天民
作者单位:山东医学院生化药物学教研室,山东医学院生化药物学教研室
摘    要:设计了一种用人脐带制备眼科用透明质酸制剂的工艺,对所得样品进行了理化分析,表明与国外产品Healon一致,动物实验表明本制剂无毒性、无刺激性,无致炎反应,对正常细胞无不良作用。

关 键 词:透明质酸  脐带  眼科用药  制药工业

THE PREPARATION AND ANALYSIS OF HYALURONIC ACID USED IN OPHTHALMOLOGY FROM HUMAN UMBILICAL CORDS
Shen Bojiang Zhang Tianmin. THE PREPARATION AND ANALYSIS OF HYALURONIC ACID USED IN OPHTHALMOLOGY FROM HUMAN UMBILICAL CORDS[J]. Journal of Shandong University:Health Sciences, 1985, 0(4)
Authors:Shen Bojiang Zhang Tianmin
Abstract:A pure, high molecular weight and sterile hyaluronic acid preparation was prepared from human umbilical cords for anterior segmental surgery. It was obtained during the process of extracting hyaluronic acid from the tissue, having the impurities such as proteins and nucleic acids removed and preparing sterile preParation. Analysis of the products was made by physical and chemical methods. The result of animal test showed no inflammatory effect. The preparation in safe to eye tissue and could be used clinically.
Keywords:Hyaluronic acid  Umbilical cord  Drug Industry  
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