| 阿托伐他汀和氯沙坦联合用药对老年单纯收缩期高血压患者脉压的影响 |
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| 引用本文： | 徐德鸿,李勇,张荣林. 阿托伐他汀和氯沙坦联合用药对老年单纯收缩期高血压患者脉压的影响[J]. 中国临床药学杂志, 2007, 16(3): 142-144 |
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| 作者姓名： | 徐德鸿 李勇 张荣林 |
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| 作者单位： | 1. 南京大学医学院附属鼓楼医院心内科,南京,210093
2. 复旦大学附属华山医院心内科,上海,200040 |
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| 摘 要： | 目的观察阿托伐他汀和氯沙坦联合用药对老年单纯收缩期高血压(ISH)患者脉压(PP)的影响。方法将62例老年ISH患者随机分为2组,对照组30例用氯沙坦片(50mg·d~(-1),po),治疗组32例用氯沙坦片(50mg·d~(-1),po)加阿托伐他汀片(20mg·d~(-1),po),观察12wk,每2周随访血压1次并记录。结果在治疗wk 12时,对照组PP从治疗前(74.67±7.77)mm Hg降至(67.37±5.53)mm Hg;治疗组PP从治疗前(75.06±6.96)mm Hg降至(59.75±5.92)mm Hg。治疗后2组PP之间差异有高度统计学意义(t=5.255,P<0.01)。结论阿托伐他汀和氯沙坦联合用药有助于改善老年ISH患者的PP。
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| 关 键 词： | 阿托伐他汀 氯沙坦 单纯收缩期高血压 脉压 |
| 文章编号： | 1007-4406（2007）03-0142-03 |
| 修稿时间： | 2006-11-20 |
Effect of combined treatment of atorvastatin and losartan on pulse pressure in senile patients with isolated systolic hypertension |
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| XU De-hong,LI Yong,ZHANG Rong-lin. Effect of combined treatment of atorvastatin and losartan on pulse pressure in senile patients with isolated systolic hypertension[J]. Chinese Journal of Clinical Pharmacy, 2007, 16(3): 142-144 |
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| Authors: | XU De-hong LI Yong ZHANG Rong-lin |
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| Affiliation: | 1.Department of Cardiovascular Medicine of Affiliated Gulou Hospital, School of Medicine, Nanfing University, Nanjing 210093, China; 2.Department of Cardiovascular Medicine,Huashan Hospital, Fudan University, Shanghai 200040, China |
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| Abstract: | |
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| Keywords: | atorvastatin losartan isolated systolic hypertension pulse pressure |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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