脑弥散性轴索损伤的临床分析

作者对６４例脑弥散性轴索损伤（ＤＡＩ）临床资料进行了分析研究，所有病例占同期重型颅脑损伤的１２．４６％，死亡率为５３．１２％，均系车祸致伤，临床表现以伤后立即陷入持续性昏迷和伴发脑干机能障碍为特征，ＭＲＩ检查有助于ＤＡＩ的临床诊断。病理发现主要为大脑半球白质、胼胝体、脑干白质的轴索广泛性损害形成收缩球，同时合并出血、梗死等局灶性病变。作者认为高压氧和神经生长因子的早期联合应用是治疗ＤＡＩ的有效方法之一。

Clinical Analysis of Diffuse Axonal Injury

Sixty cases of diffuse axonal injury were analysed in this paper. All cases were caused by traffic accident; the nortality was 53.12%. Clinical manifestations were post traumatic immediate and continuous coma with severe dysfunction of brain stem. MRI is helpful for clinical diagnosis. Pathological findings include the diffuse axonal injury of cortical while matter, corpus callosum, brain stem, and focal hemorrhage and infarction. The early use of hyperba ric oxygen combined with neuro growth factor as an effective therapy is recommended.